World Health Organization and European Network for the Study of Adrenal Tumors classification of adrenocortical carcinoma

Stage*	UICC/WHO 2004	ENSAT
I	T1, N0, M0	T1, N0, M0
II	T2, N0, M0	T2, N0, M0
III	T3, N0, M0	T3-4, N0, M0
III	T1-2, N1, M0	T1-4, N1, M0
IV	T3, N1, M0	Any M1
	T4, N0-1, M0
	Any M1

UICC: Union Internationale contre le Cancer; WHO: World Health Organization; ENSAT: European Network for the Study of Adrenal Tumors.
* T1: tumor ≤5 cm; T2: tumor >5 cm; T3: tumor infiltration in surrounding tissue; T4: tumor invasion in adjacent organs (ENSAT - also venous tumor thrombus in vena cava or renal vein); N0: no positive lymph nodes; M0: no distance metastases; N1: positive lymph nodes; M1: presence of distant metastasis.

Graphic 83901 Version 2.0

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World Health Organization and European Network for the Study of Adrenal Tumors classification of adrenocortical carcinoma