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خرید پکیج

تعداد آیتم قابل مشاهده باقیمانده : 3 مورد

Clinical manifestations of von Hippel-Lindau disease

Clinical manifestations of von Hippel-Lindau disease

	Ages at diagnosis	Most common ages at dx	Frequency in patients CNS
CNS
Retinal hemangioblastomas	0-68 yrs	12-25 yrs	25-60 percent
Endolymphatic sac tumors	12-46 yrs	24-35 yrs	10-25 percent
Cerebellar hemangioblastomas	9-78 yrs	18-25 yrs	44-72 percent
Brainstem hemangioblastomas	12-36 yrs	24-35 yrs	10-25 percent
Spinal cord hemangioblastomas	12-66 yrs	24-35 yrs	13-50 percent
Viscera
Renal cell carcinoma or cysts	16-67 yrs	25-50 yrs	25-60 percent
Pheochromocytomas*	4-58 yrs	12-25 yrs	10-20 percent^¶
Pancreatic tumor or cyst	5-70 yrs	24-35 yrs	35-70 percent
Epididymal cystadenomas	17-43 yrs	14-40 yrs	25-60 percent of males*
Adnexal papillary cystadenoma of mesonephric origin (broad ligament cystadenoma)	16-64 yrs	16-46 yrs	Estimated 10 percent of females

* Includes the 20 percent of lesions that occur outside the adrenal gland, also called paragangliomas.
¶ Frequency of pheochromocytoma varies widely depending on genotype.

Courtesy of Eric Jonasch, MD.

Graphic 83902 Version 6.0

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