Modified NIH risk stratification criteria for GIST with rupture included

Risk category	Tumor size (cm)	Mitotic index (per 50 HPFs)	Primary tumor site
Very low risk	<2.0	≤5	Any
Low risk	2.1 to 5.0	≤5	Any
Intermediate risk	2.1 to 5.0	>5	Gastric
	<5.0	6 to 10	Any
	5.1 to 10.0	≤5	Gastric
High risk	Any	Any	Tumor rupture
	>10 cm	Any	Any
	Any	>10	Any
	>5.0	>5	Any
	2.1 to 5.0	>5	Nongastric
	5.1 to 10.0	≤5	Nongastric

NIH: National Institutes of Health; GIST: gastrointestinal stromal tumor; HPF: high power fields.

Reproduced from: Joensuu H. Risk stratification of patients diagnosed with gastrointestinal stromal tumor. Hum Pathol 2008; 39:1411. Table used with the permission of Elsevier Inc. All rights reserved.

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