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خرید پکیج
تعداد آیتم قابل مشاهده باقیمانده : 3 مورد
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Immunohistochemical staining of select cutaneous tumors

Immunohistochemical staining of select cutaneous tumors
  >25% p53[1] Ki 67[1] Ber EP4 p63[2] CEA AE14[3] CK 20 CK 15[4] CK 7[4] AR[7]
MAC 20% <5%

0%[5]

38%[4]		 Peripheral staining 100%

50%[3]

54%[4]		 100% 0%[4,6] 92% 15% Negative
BCC 80% 20 to 40%

100%[5]

100%[4]		 Diffuse 100% 0%[3,4]   0%[4,6] 0% 40% Positive
DTE 0% Rare

75%[5]

50%[4]		 Diffuse 100% 0%[3,4] 0%

12%[4]

100%[6]		 100% 0% Negative
Syringoma         100%[4] 33%       --
SCC     38%[4]   0%[4]   0%[4] 0% 12% --
MAC: microcystic adnexal carcinoma; BCC: basal cell carcinoma; DTE: desmoplastic trichoepithelioma; SCC: squamous cell carcinoma.
References:
  1. Smith KL, Williams J, Corbett D, Skelton H. Microcystic adnexal carcinoma: An immunohistochemical study including markers of proliferation and apoptosis. Am J Surg Pathol 2001; 25:464.
  2. Vidal CI, Goldberg M, Burstein DE, et al. p63 Immunohistochemistry is a useful adjunct in distinguishing sclerosing cutaneous tumors. Am J Dermatopathol 2010; 32:257.
  3. Wick MR, Cooper PH, Swanson PE, et al. Microcystic adnexal carcinoma. An immunohistochemical comparison with other cutaneous appendage tumors. Arch Dermatol 1990; 126:189.
  4. Hoang MP, Dresser KA, Kapur P, et al. Microcystic adnexal carcinoma: an immunohistochemical reappraisal. Mod Pathol 2008; 21:178.
  5. Krahl D, Sellheyer K. Monoclonal antibody Ber-EP4 reliably discriminates between microcystic adnexal carcinoma and basal cell carcinoma. J Cutan Pathol 2007; 34:782.
  6. Abesamis-Cubillan E, El-Shabrawi-Caelen L, Leboit PE. Merked cells and sclerosing epithelial neoplasms. Am J Dermatopathol 2000; 22:311.
  7. Evangelista MT, North JP. Comparative analysis of cytokeratin 15, TDAG51, cytokeratin 20 and androgen receptor in sclerosing adnexal neoplasms and variants of basal cell carcinoma. J Cutan Pathol 2015;42:824.
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