Mitochondrial pathways in the erythroblast affected by genetic defects of congenital sideroblastic anemias

A38 (after glycine): SLC25A38; CoA: coenzyme A; ALA: 5-aminolevulinic acid; CP'gen III: coproporphyrinogen III; PPIX: protoporphyrin IX; Fe: iron; MFRN1 (after iron [Fe]): mitoferrin 1; Fe-S: iron-sulfur; ABCB7 (after Fe-S cluster synthesis): mitochondrial transporter for cytosolic Fe-S cluster maturation; Thiamine-P-P: thiamine pyrophosphate; tRNA: transfer RNA; mt: mitochondrial; ALAS2: 5-aminolevulinate synthase; SLC25A38: mitochondrial glycine carrier protein; FECH: ferrochelatase; HSPA9: mitochondrial heat shock protein 70 homologue; HCSB: mitochondrial Fe-S cluster assembly co-chaperone; PUS1: pseudouridine synthase; YARS2: tyrosyl-tRNA synthetase; LARS2: leucyl-tRNA synthetase; IARS2: isoleucyl-tRNA synthetase; SARS2: seryl-tRNA synthetase; TRNT1: tRNA nucleotidyl transferase 1 (CCA-adding enzyme); NDUFB11: NADH:ubiquinone oxidoreductase subunit B11; MT-ATP6: mitochondrial ATP synthase 6; SLC19A2: high-affinity thiamine transporter.