DMARDs for rheumatologic diseases (including rheumatoid arthritis and psoriatic arthritis)

Generic name	Example brand name(s)	How it is usually taken
Conventional synthetic DMARDs
Azathioprine	Imuran, Azasan	Pill
Hydroxychloroquine	Plaquenil	Pill
Leflunomide	Arava	Pill
Methotrexate	Pills: Rheumatrex, Trexall Autoinjectors (these let you give yourself a shot): Otrexup, Rasuvo Prefilled syringe (this lets you give yourself a shot): RediTrex	Pill or shot under the skin or in a muscle. Important: Methotrexate is only taken once per week. Always double-check the instructions with your doctor and pharmacist when you get a new prescription. If you need to take methotrexate for a long time, your doctor will suggest taking a folic acid supplement. This can help lower the risk of side effects.
Sulfasalazine	Azulfidine, Azulfidine EN tabs	Pill
Biologic DMARDs
Abatacept	Orencia	Shot under the skin or into a vein (by IV) at a clinic or doctor's office
Adalimumab	Abrilada, Amjevita, Cyltezo, Hadlima, Hulio, Humira, Hyrimoz, Idacio, Yuflyma, Yusimry	Shot under the skin
Anakinra	Kineret	Shot under the skin
Certolizumab pegol	Cimzia	Shot under the skin
Etanercept	Enbrel	Shot under the skin
Golimumab	Simponi	Shot under the skin or into a vein (by IV) at a clinic or doctor's office
Guselkumab	Tremfya	Shot under the skin
Infliximab	Avsol, Inflectra, Remicade, Renflexis	Into a vein (by IV) at a clinic or doctor's office
Ixekizumab	Taltz	Shot under the skin
Risankizumab	Skyrizi	Shot under the skin
Rituximab	Riabni, Rituxan, Ruxience, Truxima	Into a vein (by IV) at a clinic or doctor's office
Sarilumab	Kevzara	Shot under the skin
Secukinumab	Cosentyx	Shot under the skin
Tocilizumab	Actemra	Shot under the skin or into a vein (by IV) at a clinic or doctor's office
Ustekinumab	Stelara	Shot under the skin
Targeted synthetic DMARDs
Baricitinib	Olumiant	Pill
Tofacitinib	Xeljanz	Pill
Upadacitinib	Rinvoq	Pill

This table lists some of the available DMARDs in the US. Your doctor will talk to you about how often you need to take your medicine. The exact schedule and instructions will depend on which medicine you take, as well as your situation. If your medicine comes as a shot that goes under the skin, you or a caregiver will be trained on how to do this.

Graphic 86815 Version 13.0

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DMARDs for rheumatologic diseases (including rheumatoid arthritis and psoriatic arthritis)