Treatment of EGFR inhibitor-induced acneiform rash

EGFR: epidermal growth factor receptor; CTCAE: Common Terminology Criteria for Adverse Events; SPF: sun protection factor; ADL: activities of daily living; PI: prescribing information.
* It is recommended that patients treated with EGFR inhibitors begin prophylactic rash therapy with doxycycline 100 mg twice a day or minocycline 100 mg daily and a low-potency topical steroid twice a day for the first 6 weeks of therapy.

Source:

Modified from: Balagula E, Lacouture ME. Dermatologic toxicities. In: The MASCC Textbook of Cancer Supportive Care and Survivorship, Olver IN (Ed), Springer, New York 2010. Copyright © 2010; with kind permission from Springer Science + Business Media B.V.
NCITCAE v.5 grade definitions reproduced from: Common Terminology Criteria for Adverse Events (CTCAE), Version 5.0, November 2017, National Institutes of Health, National Cancer Institute. Available at: https://ctep.cancer.gov/protocoldevelopment/electronic_applications/docs/CTCAE_v5_Quick_Reference_8.5x11.pdf (Accessed March 27, 2018).

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Treatment of EGFR inhibitor-induced acneiform rash