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Fructose, dextrose, and orthophosphoric acid: Drug information

Fructose, dextrose, and orthophosphoric acid: Drug information
(For additional information see "Fructose, dextrose, and orthophosphoric acid: Patient drug information")

For abbreviations, symbols, and age group definitions used in Lexicomp (show table)
Brand Names: US
  • Anti-Nausea [OTC];
  • Emetrol [OTC];
  • Formula EM [OTC] [DSC]
Pharmacologic Category
  • Antiemetic
Dosing: Adult
Nausea

Nausea: Oral: 15 to 30 mL; repeat dose every 15 minutes until distress subsides; do not take >5 doses in 1 hour.

Dosing: Kidney Impairment: Adult

There are no dosage adjustments provided in the manufacturer's labeling.

Dosing: Hepatic Impairment: Adult

There are no dosage adjustments provided in the manufacturer's labeling.

Dosing: Older Adult

Refer to adult dosing.

Dosing: Pediatric
Nausea

Nausea: Oral

Children 2 to 12 years: 5 to 10 mL; repeat dose every 15 minutes until distress subsides; do not take for more than 1 hour (5 doses)

Children ≥12 years: Refer to adult dosing.

Adverse Reactions

There are no adverse reactions listed in the manufacturer's labeling. See Dextrose monograph.

Contraindications

OTC labeling: When used for self-medication, do not use if you have ever had an allergic reaction to fructose, dextrose, phosphoric acid, or any component of the formulation, or if you have hereditary fructose intolerance.

Warnings/Precautions

Other warnings/precautions:

• Self-medication (OTC use): When used for self-medication (OTC), check with health care provider before use if you have diabetes. Notify health care provider if symptoms persist, return, or worsen, or if you need >5 doses in 1 hour.

Dosage Forms: US

Excipient information presented when available (limited, particularly for generics); consult specific product labeling. [DSC] = Discontinued product

Solution, Oral:

Anti-Nausea: Fructose 1.87 g, dextrose 1.87 g, and phosphoric acid 21.5 mg per 5 mL (118 mL) [antihistamine free, caffeine free, salicylate free; contains fd&c red #40 (allura red ac dye), methylparaben; cherry flavor]

Emetrol: Fructose 1.87 g, dextrose 1.87 g, and phosphoric acid 21.5 mg per 5 mL (118 mL [DSC]) [lemon-mint flavor]

Emetrol: Fructose 1.87 g, dextrose 1.87 g, and phosphoric acid 21.5 mg per 5 mL (118 mL) [acetaminophen free, alcohol free, antihistamine free, aspirin free, caffeine free; contains fd&c red #40 (allura red ac dye), methylparaben; cherry flavor]

Formula EM: Fructose 1.87 g, dextrose 1.87 g, and phosphoric acid 21.5 mg per 5 mL (118 mL [DSC]) [cherry flavor]

Generic Equivalent Available: US

Yes

Pricing: US

Solution (Emetrol Oral)

1.87-1.87-21.5 (per mL): $0.06

Disclaimer: A representative AWP (Average Wholesale Price) price or price range is provided as reference price only. A range is provided when more than one manufacturer's AWP price is available and uses the low and high price reported by the manufacturers to determine the range. The pricing data should be used for benchmarking purposes only, and as such should not be used alone to set or adjudicate any prices for reimbursement or purchasing functions or considered to be an exact price for a single product and/or manufacturer. Medi-Span expressly disclaims all warranties of any kind or nature, whether express or implied, and assumes no liability with respect to accuracy of price or price range data published in its solutions. In no event shall Medi-Span be liable for special, indirect, incidental, or consequential damages arising from use of price or price range data. Pricing data is updated monthly.

Administration: Adult

Oral: Should not be diluted or followed with other fluids immediately before or after administration. Use dosing cup (if provided) or an accurate measuring device (if one is not provided) to measure doses.

Administration: Pediatric

Oral: Do not dilute or drink other fluids immediately before or after administration.

Use: Labeled Indications

Nausea: Relief of nausea associated with upset stomach that occurs with intestinal or stomach flu, and food indiscretions.

Metabolism/Transport Effects

None known.

Drug Interactions

There are no known significant interactions.

Brand Names: International
International Brand Names by Country
For country code abbreviations (show table)

  • (AU) Australia: Anvatrol | Emetrol;
  • (HK) Hong Kong: Emetrol;
  • (IL) Israel: Peptical;
  • (PR) Puerto Rico: Formula em | Kalmz | Nausatrol | Nausetrol
  1. Emetrol (phosphorated carbohydrate solution) [prescribing information]. Sarasota, FL: WellSpring Pharmaceutical Corporation; received May 2021.
  2. Formula EM (glucose, fructose, and phosphoric acid solution) [prescribing information]. Livonia, MI: Major Pharmaceuticals; May 2018.
  3. Select Brand Anti-Nausea (phosphorated carbohydrate solution) [prescribing information]. Pine Bluff, AR: Select Brand Distributors; December 2020.
Topic 8705 Version 135.0

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