Drugs useful in palliative care that can be administered rectally

Opioid analgesics	Corticosteroids	NSAIDs	Anxiolytics	Laxatives	Anti-emetics	Anti-epileptics
Morphine*	Hydrocortisone	Acetaminophen*	Diazepam*	Glycerin*	Prochlorperazine*	Phenobarbital
Hydromorphone*	Prednisolone	Diclofenac	Lorazepam	Sodium phosphates*	Promethazine*	Pentobarbital
Methadone	Dexamethasone	Indomethacin*	Midazolam	Mineral oil*	Chlorpromazine	Phenytoin
Oxycodone		Ibuprofen	Clonazepam	Bisacodyl*	Metoclopramide	Carbamazepine
Codeine		Naproxen		Docusate*	Ondansetron	Valproic acid
Tramadol		Aspirin				Lamotrigine

NSAIDs: nonsteroidal antiinflammatory drugs.
* Commercially available as a suppository or enema in the United States.

Reproduced with permission from: Samala RV, Davis MP. Use of Rectal Meds for Palliative Care Patients. Fast Facts and Concepts. September 2012; 257. Available at: https://www.mypcnow.org/blank-rskfm. Copyright © 2012 EPERC.

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Drugs useful in palliative care that can be administered rectally