Short-term and long-term adverse effects of UVB phototherapy

Acute
Sunburn or phototoxic reaction if overdosed	++
Phototoxic reaction from accidental intake of a photosensitizer	–
Conjunctivitis, keratitis (if no eye shielding is used)	++
Provocation of photodermatoses (eg, polymorphous light eruption)	+
Chronic
Lentigines	+
Photoaging	++
Actinic keratosis, nonmelanoma skin cancer	+/±
Melanoma	?

–: no risk; ++: high risk; +: medium risk; ±: low risk; ?: possible, insufficient data.

Most photosensitizing substances absorb in the UVA range. Thus, exposure to UVB after the accidental ingestion of a photosensitizer does not induce a phototoxic reaction.

Graphic 87496 Version 2.0

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