Genetic polymorphisms associated with obesity risk

Obesity-susceptible loci discovered in 4 waves of GWAS for BMI (blue), 3 waves of GWAS for waist circumference (purple) and WHRadj (red), and 2 waves of GWAS for extreme and early onset of obesity (green). Each Venn diagram represents the loci of 1 paper.

BMI: body mass index; WHRadj: waist-to-hip ratio (adjusted); GWAS: genome-wide association studies.

Reproduced from: Loos RJF. The genetic determinants of common obesity-susceptibility. In: Adipose tissue biology. Symonds ME (Ed), New York, Springer 2011. Copyright © 2011; with kind permission from Springer Science + Business Media B.V.

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