ﺑﺎﺯﮔﺸﺖ ﺑﻪ ﺻﻔﺤﻪ ﻗﺒﻠﯽ
خرید پکیج
تعداد آیتم قابل مشاهده باقیمانده : 3 مورد
نسخه الکترونیک
medimedia.ir

Castor oil: Drug information

Castor oil: Drug information
(For additional information see "Castor oil: Pediatric drug information")

For abbreviations, symbols, and age group definitions used in Lexicomp (show table)
Brand Names: US
  • GoodSense Castor Oil [OTC]
Pharmacologic Category
  • Laxative, Miscellaneous
Dosing: Adult
Bowel evacuation, constipation

Bowel evacuation, constipation: Oil: Oral: 15 to 60 mL as a single dose.

Dosing: Older Adult

Refer to adult dosing.

Dosing: Pediatric

(For additional information see "Castor oil: Pediatric drug information")

Note: Produces bowel evacuation in 6 to 12 hours. Use of castor oil has generally been replaced with other laxatives (eg, PEG solutions, lactulose) less likely to cause adverse effects (eg, electrolyte disturbances) (Ref):

Constipation, occasional

Constipation, occasional: Oral:

Children 2 to 11 years: 5 to 15 mL as a single daily dose as needed

Children ≥12 years and Adolescents: 15 to 60 mL as a single daily dose as needed

Dosing: Kidney Impairment: Pediatric

There are no dosage adjustments provided in the manufacturer’s labeling.

Dosing: Hepatic Impairment: Pediatric

There are no dosage adjustments provided in the manufacturer’s labeling.

Adverse Reactions

There are no adverse reactions listed in the manufacturer's labeling.

Warnings/Precautions

Other warnings/precautions:

• Appropriate use: Do not use for longer than 1 week or when abdominal pain, nausea, vomiting, or rectal bleeding are present unless directed by health care provider.

Dosage Forms: US

Excipient information presented when available (limited, particularly for generics); consult specific product labeling.

Oil, Oral:

GoodSense: (118 mL)

Generic: (59 mL, 118 mL, 177 mL, 473 mL)

Generic Equivalent Available: US

No

Pricing: US

Oil (Castor Oil Oral)

100% (per mL): $0.02

Disclaimer: A representative AWP (Average Wholesale Price) price or price range is provided as reference price only. A range is provided when more than one manufacturer's AWP price is available and uses the low and high price reported by the manufacturers to determine the range. The pricing data should be used for benchmarking purposes only, and as such should not be used alone to set or adjudicate any prices for reimbursement or purchasing functions or considered to be an exact price for a single product and/or manufacturer. Medi-Span expressly disclaims all warranties of any kind or nature, whether express or implied, and assumes no liability with respect to accuracy of price or price range data published in its solutions. In no event shall Medi-Span be liable for special, indirect, incidental, or consequential damages arising from use of price or price range data. Pricing data is updated monthly.

Administration: Adult

Do not administer at bedtime because of rapid onset of action. Should be administered on an empty stomach with juice or carbonated beverages.

Administration: Pediatric

Oral: Do not administer at bedtime because of rapid onset of action; chill or administer with milk, juice, or carbonated beverage to improve palatability; administer on an empty stomach for quicker onset (Ref).

Use: Labeled Indications

Bowel evacuation/constipation: Temporary relief of occasional constipation.

Metabolism/Transport Effects

None known.

Drug Interactions

Note: Interacting drugs may not be individually listed below if they are part of a group interaction (eg, individual drugs within “CYP3A4 Inducers [Strong]” are NOT listed). For a complete list of drug interactions by individual drug name and detailed management recommendations, use the Lexicomp drug interactions program by clicking on the “Launch drug interactions program” link above.

Polyethylene Glycol-Electrolyte Solution: Laxatives (Stimulant) may enhance the adverse/toxic effect of Polyethylene Glycol-Electrolyte Solution. Specifically, the risk of colonic mucosal aphthous ulcerations may be increased. Management: Consider avoiding this combination due to a potential for increased risk of colonic mucosal aphthous ulcerations. Risk D: Consider therapy modification

Sodium Sulfate: Laxatives (Stimulant) may enhance the adverse/toxic effect of Sodium Sulfate. Specifically, the risk of mucosal ulceration or ischemic colitis may be increased. Risk X: Avoid combination

Pregnancy Considerations

Ingestion of castor oil may be associated with induction of labor. Use of castor oil as a laxative during pregnancy should be avoided (Cullen 2007; Hall 2011; Wald 2003).

Dietary Considerations

Should be taken on an empty stomach with juice or carbonated beverages.

Mechanism of Action

Acts primarily in the small intestine; hydrolyzed to ricinoleic acid which reduces net absorption of fluid and electrolytes and stimulates peristalsis

Pharmacokinetics (Adult Data Unless Noted)

Onset of action: 1 to 3 hours (Brunton 2006) but may take up to 12 hours

Brand Names: International
International Brand Names by Country
For country code abbreviations (show table)

  • (AE) United Arab Emirates: Castor oil;
  • (AR) Argentina: Aceite ricino;
  • (AU) Australia: Castor oil | Gold cross castor oil;
  • (BG) Bulgaria: Oleum ricini;
  • (BR) Brazil: Mana infantil | Oleo de ricino | Ricinol;
  • (CN) China: Bi ma;
  • (CO) Colombia: Aceite de ricino | Aceite ricino;
  • (DE) Germany: Daileys Ideal Rizinusoel | Rizinus castor | Rizinusoel | Zirkulin rizinusoel;
  • (EE) Estonia: Eurocare castor;
  • (EG) Egypt: Castor oil;
  • (ES) Spain: Aceite de Ricino Brum | Aceite de Ricino Orravan;
  • (FR) France: Huile de Ricin Cooper;
  • (GB) United Kingdom: Castor oil;
  • (GR) Greece: Castor oil;
  • (IE) Ireland: Castor oil;
  • (IN) India: Castor oil | Erand | Erand tail;
  • (IR) Iran, Islamic Republic of: Laxaricin;
  • (JO) Jordan: Castor oil;
  • (JP) Japan: Castor oil | Castor yoshida;
  • (KW) Kuwait: Castor oil;
  • (LT) Lithuania: Oleum ricini | Ricinos aliejus;
  • (LV) Latvia: Oleum ricini | Ricinella;
  • (MX) Mexico: Aceite de ricino;
  • (NG) Nigeria: Castor oil;
  • (PE) Peru: Aceite ricino;
  • (PL) Poland: Olej Rycynowy | Oleum ricini;
  • (PR) Puerto Rico: Castor oil;
  • (RU) Russian Federation: Oleum ricini | Ricini oleum;
  • (TH) Thailand: Castor oil | Castor oil (white);
  • (TW) Taiwan: Castor oil | Oleum ricini;
  • (UA) Ukraine: Oleum ricini;
  • (ZA) South Africa: Castor oil | Marshalls castor oil
  1. Brunton LL, Chabner BA, Knollmann BC, eds. Goodman & Gilman’s The Pharmacological Basis of Therapeutics. 11th ed. New York, NY: McGraw-Hill Medical; 2006.
  2. Cullen G, O'Donoghue D. Constipation and pregnancy. Best Pract Res Clin Gastroenterol. 2007;21(5):807-818. [PubMed 17889809]
  3. GoodSense Castor Oil [prescribing information]. St. Louis, MO: Vi-Jon Inc; May 2020.
  4. Hall HG, McKenna LG, Griffiths DL. Complementary and alternative medicine for induction of labour. Women Birth. 2012;25(3):142-148. [PubMed 21524953]
  5. Humco Castor Oil liquid [prescribing information]. Texarkana, TX; Humco; October 2013.
  6. Tabbers MM, DiLorenzo C, Berger MY, et al. Evaluation and treatment of functional constipation in infants and children: evidence-based recommendations from ESPGHAN and NASPGHAN. J Pediatr Gastroenterol Nutr. 2014;58(2):258-274. [PubMed 24345831]
  7. Wald A. Constipation, diarrhea, and symptomatic hemorrhoids during pregnancy. Gastroenterol Clin North Am. 2003;32(1):309-322. [PubMed 12635420]
Topic 8846 Version 97.0

آیا می خواهید مدیلیب را به صفحه اصلی خود اضافه کنید؟