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خرید پکیج
تعداد آیتم قابل مشاهده باقیمانده : 3 مورد
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Multimodality data comparing pleurectomy/decortication and extrapleural pneumonectomy

Multimodality data comparing pleurectomy/decortication and extrapleural pneumonectomy
Ref Procedure n 30 d mortality
(percent)		 Morbidity
(percent)		 Median fu (months)

Median OS (months)

 2 year
(percent)		 5 year
(percent)
Lang-Lazdunski[1] P/D
(V/P/dgm/peri)		 54 0 28 15.7 23 49 30.1
EPP 22 4.5 68 12.9 12.8 18.2 9
Rena[2] P/D
(? extended)		 37 0 24 2-45 25 55 NA
EPP 40 5 62 10-41 20 35 NA
Sorensen[3] P/D 34 0 NR – 28.4 – 27
EPP 28 0 NR – 31.9 – 16
Pass[4] P/D
(all stages, 24 extended)		 78 1.3 22 22
(0-204)		 23 46 19
EPP 102 4.9 57 12
(0-118)		 12 23 5
  P/D Stage I/II
(11 extended)		 38 2 20 35
(0-204)		 44 66 35
EPP Stage I/II 20 5 30 27.5
(0-105)		 25 55 29
 Bovolato[5]
 		 P/D 204 2.6 10 80 20.5 40 10
EPP 301 4.1 22 80 18.8 37 12
 Flores[6] P/D

278

 4 - 17 16 - -
EPP  385 7 - 17 12 - -
 Burt[7] P/D 130 3.1 4 - - - -
EPP 95 10.5 24 - - - -
OS: overall survival; P/D: pleurectomy decortication; V/P: visceral/parietal; dgm: diaphragm; peri: pericardium; fu: followup.
References:
  1. Lang-Lazdunski L, et al. Pleurectomy/decortication is superior to extrapleural pneumonectomy in the multimodality management of patients with malignant pleural mesothelioma. J Thorac Oncol 7(4):737, 2012.
  2. Rena O, et al. Extrapleural pneumonectomy for early stage malignant pleural mesothelioma: a harmful procedure. Lung Cancer 77(1):151, 2012.
  3. Two Simultaneous Consecutive Non-Randomized Cohorts of Operable Patients with MPM Receiving Induction Therapy Followed either by EPP and Postoperative Radiotherapy or Pleurectomy Decortication Alone. 11th International Conference of the International Mesothelioma Interest Group. 2012; 2012.
  4. Pass H. Mesothelioma Revisited: A Multidisciplinary Approach. Third ESMO European Lung Cancer Conference; 12 Apr 19; 2012.
  5. Bovolato P, et al. Does surgery improve survival of patients with malignant pleural mesothelioma? A multicenter retrospective analysis of 1365 consecutive patients. J Thorac Oncol 2014; 9(3):390.
  6. Flores RM, et al. Extrapleural pneumonectomy versus pleurectomy/decortication in the surgical management of malignant pleural mesothelioma: results in 663 patients. J Thorac Cardiovasc Surg 2008; 135:620.
  7. Burt BM, et al. Malignant pleural mesothelioma and the Society of Thoracic Surgeons Database: an analysis of surgical morbidity and mortality. J Thorac Cardiovasc Surg 2014; 148:30. 
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