Factors that blunt the normal counterregulatory response to exercise or hypoglycemia
Several factors blunt the counterregulatory hormone response to exercise and to subsequent hypoglycemia, which contribute to a vicious cycle that predisposes the individual to a further deterioration in glucose control.
References:
- Galassetti P, Tate D, Neill RA, Morrey S, Wasserman DH, Davis SN. Effect of sex on counter-regulatory responses to exercise after antecedent hypoglycemia in Type 1 diabetes. Am J Physiol Endocrinol Metab. 2004 Jul; 287(1):E16-24.
- Galassetti P, Neill AR, Tate D, Ertl AC, Wasserman DH, Davis SN. Sexual dimorphism in counter-regulatory responses to hypoglycemia after antecedent exercise. J Clin Endocrinol Metab. 2001; 86:3516-24.
Adapted from: Tsintzas K, MacDonald IA. Endocrine and metabolic responses to exercise. In: Type 1 diabetes: Clinical management of the athlete, Gallen I (Ed), Springer-Verlag, London, 2012.
