Version July 2025
Antiseptic: Topical: Apply small amount to affected area 1 to 3 times daily.
Mouth/throat pain: Oral:
Lozenge: 1 lozenge every 2 hours as needed (maximum: 10 lozenges/day).
Solution: Apply to affected area or gargle and swish for 1 minute, then expectorate; may use up to 4 times daily or as directed by health care provider.
There are no dosage adjustments provided in the manufacturer's labeling.
There are no dosage adjustments provided in the manufacturer's labeling.
Refer to adult dosing.
Sore throat: Oral: Children ≥6 years: Refer to adult dosing.
There are no adverse reactions listed in the manufacturer's labeling.
Dosage form specific issues:
• Antiseptic (self-medication, OTC use): Do not use in eyes or apply to large areas of the body; patients should contact health care provider prior to use on deep or puncture wounds, animal bites, or severe burns and if irritation, pain, or redness persist or worsen.
• Mouth/throat pain (self-medication, OTC use): When self-medicating, patients should be instructed to contact healthcare provider if symptoms last >7 days; when treating a severe sore throat, patients should contact healthcare provider if symptoms lasts >2 days and if accompanied by fever, rash, nausea, or vomiting; or if symptoms worsen.
Excipient information presented when available (limited, particularly for generics); consult specific product labeling.
Lozenge, Mouth/Throat:
Mucinex InstaSoothe Throat/Cmf: 2.4 mg (20 ea, 40 ea) [contains fd&c yellow #6 (sunset yellow), quinoline yellow (d&c yellow #10)]
Mucinex InstaSoothe Throat/Pn: 2 mg (20 ea, 40 ea) [contains fd&c blue #1 (brilliant blue), fd&c red #40 (allura red ac dye)]
No
Oral: Lozenge: Allow lozenge to dissolve slowly in mouth.
Topical: Clean affected area prior to applying. Allow to dry prior to covering with sterile bandage.
Oral: Allow lozenge to dissolve slowly.
Antiseptic: First aid antiseptic to protect minor cuts, scrapes, or burns from skin infection.
Mouth/throat pain: Temporary relief of minor sore throat pain, sore mouth, minor mouth pain, or mouth irritation.
None known.
Note: Interacting drugs may not be individually listed below if they are part of a group interaction (eg, individual drugs within “CYP3A4 Inducers [Strong]” are NOT listed). For a complete list of drug interactions by individual drug name and detailed management recommendations, use the drug interactions program by clicking on the “Launch drug interactions program” link above.
Articaine: May increase adverse/toxic effects of Local Anesthetics. Risk C: Monitor
Methemoglobinemia Associated Agents: May increase adverse/toxic effects of Local Anesthetics. Specifically, the risk for methemoglobinemia may be increased. Risk C: Monitor
ROPivacaine: May increase adverse/toxic effects of Local Anesthetics. Risk C: Monitor
