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Hexylresorcinol: Drug information

Hexylresorcinol: Drug information
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For abbreviations, symbols, and age group definitions show table
Brand Names: US
  • Mucinex InstaSoothe Throat/Cmf [OTC];
  • Mucinex InstaSoothe Throat/Pn [OTC]
Pharmacologic Category
  • Antiseptic, Topical;
  • Local Anesthetic
Dosing: Adult
Antiseptic

Antiseptic: Topical: Apply small amount to affected area 1 to 3 times daily.

Mouth/throat pain

Mouth/throat pain: Oral:

Lozenge: 1 lozenge every 2 hours as needed (maximum: 10 lozenges/day).

Solution: Apply to affected area or gargle and swish for 1 minute, then expectorate; may use up to 4 times daily or as directed by health care provider.

Dosing: Kidney Impairment: Adult

There are no dosage adjustments provided in the manufacturer's labeling.

Dosing: Liver Impairment: Adult

There are no dosage adjustments provided in the manufacturer's labeling.

Dosing: Older Adult

Refer to adult dosing.

Dosing: Pediatric
Sore throat

Sore throat: Oral: Children ≥6 years: Refer to adult dosing.

Adverse Reactions

There are no adverse reactions listed in the manufacturer's labeling.

Warnings/Precautions

Dosage form specific issues:

• Antiseptic (self-medication, OTC use): Do not use in eyes or apply to large areas of the body; patients should contact health care provider prior to use on deep or puncture wounds, animal bites, or severe burns and if irritation, pain, or redness persist or worsen.

• Mouth/throat pain (self-medication, OTC use): When self-medicating, patients should be instructed to contact healthcare provider if symptoms last >7 days; when treating a severe sore throat, patients should contact healthcare provider if symptoms lasts >2 days and if accompanied by fever, rash, nausea, or vomiting; or if symptoms worsen.

Dosage Forms: US

Excipient information presented when available (limited, particularly for generics); consult specific product labeling.

Lozenge, Mouth/Throat:

Mucinex InstaSoothe Throat/Cmf: 2.4 mg (20 ea, 40 ea) [contains fd&c yellow #6 (sunset yellow), quinoline yellow (d&c yellow #10)]

Mucinex InstaSoothe Throat/Pn: 2 mg (20 ea, 40 ea) [contains fd&c blue #1 (brilliant blue), fd&c red #40 (allura red ac dye)]

Generic Equivalent Available: US

No

Pricing: US

Lozenge (Mucinex InstaSoothe Throat/Cmf Mouth/Throat)

2.4 mg (per each): $0.15

Lozenge (Mucinex InstaSoothe Throat/Pn Mouth/Throat)

2 mg (per each): $0.15

Disclaimer: A representative AWP (Average Wholesale Price) price or price range is provided as reference price only. A range is provided when more than one manufacturer's AWP price is available and uses the low and high price reported by the manufacturers to determine the range. The pricing data should be used for benchmarking purposes only, and as such should not be used alone to set or adjudicate any prices for reimbursement or purchasing functions or considered to be an exact price for a single product and/or manufacturer. Medi-Span expressly disclaims all warranties of any kind or nature, whether express or implied, and assumes no liability with respect to accuracy of price or price range data published in its solutions. In no event shall Medi-Span be liable for special, indirect, incidental, or consequential damages arising from use of price or price range data. Pricing data is updated monthly.

Administration: Adult

Oral: Lozenge: Allow lozenge to dissolve slowly in mouth.

Topical: Clean affected area prior to applying. Allow to dry prior to covering with sterile bandage.

Administration: Pediatric

Oral: Allow lozenge to dissolve slowly.

Use: Labeled Indications

Antiseptic: First aid antiseptic to protect minor cuts, scrapes, or burns from skin infection.

Mouth/throat pain: Temporary relief of minor sore throat pain, sore mouth, minor mouth pain, or mouth irritation.

Metabolism/Transport Effects

None known.

Drug Interactions

Note: Interacting drugs may not be individually listed below if they are part of a group interaction (eg, individual drugs within “CYP3A4 Inducers [Strong]” are NOT listed). For a complete list of drug interactions by individual drug name and detailed management recommendations, use the drug interactions program by clicking on the “Launch drug interactions program” link above.

Articaine: May increase adverse/toxic effects of Local Anesthetics. Risk C: Monitor

Methemoglobinemia Associated Agents: May increase adverse/toxic effects of Local Anesthetics. Specifically, the risk for methemoglobinemia may be increased. Risk C: Monitor

ROPivacaine: May increase adverse/toxic effects of Local Anesthetics. Risk C: Monitor

Brand Names: International
International Brand Names by Country
For country code abbreviations (show table)

  • (AE) United Arab Emirates: Lemsip sore throat;
  • (AU) Australia: Anticol max numbing | Listerine | Nyal;
  • (GB) United Kingdom: Asda dual action | Boots Sore Throat Relief Dual Action Lozenges | Boots triple action sore throat relief | Dual action honey&lemon | Halls Sore Throat Relief Dual Action | Lemsip sore throat | Mac | Mac dual action | Morrisons dual action antiseptic throat lozenges | Sore throat relief dual action | Strepsils extra | Strepsils Extra Blackcurrant | Strepsils Extra Cherry | Strepsils Extra Citrus Menthol | Sucrets | Superdrug sore throat dual action;
  • (HK) Hong Kong: Difflam hextra;
  • (IL) Israel: Sucrets;
  • (IN) India: Strepsils pain relief;
  • (JO) Jordan: Strepsils extra;
  • (KW) Kuwait: Strepsils extra;
  • (LB) Lebanon: Strepsils extra;
  • (MY) Malaysia: Difflam hextra | Mac | Strepsils max;
  • (PH) Philippines: Listerine | Strepsils max;
  • (PR) Puerto Rico: Listerine;
  • (QA) Qatar: Strepsils Extra Triple Action;
  • (SG) Singapore: Eze | Strepsils max | Troti pront max | Viocil;
  • (TR) Turkey: Septisil;
  • (VE) Venezuela, Bolivarian Republic of: Listerine
  1. Maximum Strength Sore Throat Lozenges (hexylresorcinol) [prescribing information]. Valley Forge, PA: AmerisourceBergen; May 2007.
  2. Mint Sore Throat Lozenges (hexylresorcinol) [prescribing information]. San Francisco, CA: McKesson; received December 2008.
  3. S.T.37 (hexylresorcinol) [prescribing information]. Solon, OH: Numark Brands Inc; March 2018.
  4. Sucrets Sore Throat (hexylresorcinol) [prescribing information]. Blue Bell, PA: Insight Pharmaceuticals; received November 2007.
Topic 8972 Version 87.0

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