(For additional information
see "Hydroxypropyl methylcellulose: Patient drug information")
For abbreviations, symbols, and age group definitions used in Lexicomp (
show table)
Brand Names: US
- Alcon Tears [OTC];
- GenTeal Severe [OTC];
- Gonak [OTC] [DSC];
- Goniosoft [OTC] [DSC];
- Goniotaire [OTC];
- ImproVue [OTC];
- Isopto Tears [OTC] [DSC];
- OcuCoat Viscoadherent [DSC];
- Pure & Gentle Lubricant [OTC];
- Vista Gel Dry Eye Relief [OTC] [DSC];
- Vista Gonio Dry Eye Relief [OTC]
Pharmacologic Category
-
Diagnostic Agent, Ophthalmic;
-
Lubricant, Ocular
Dosing: Adult
Eye irritation
Eye irritation: Ophthalmic: Instill 1 to 2 drops in affected eye(s) as needed.
Gonioscopic examination aid
Gonioscopic examination aid: Gonak, Goniosoft: Ophthalmic: Fill gonioscopic prism with solution as necessary.
Ophthalmic surgical aid
Ophthalmic surgical aid: OcuCoat Viscoelastic: Ophthalmic: Use during ophthalmic surgery as directed; consult specific product instructions.
Dosing: Kidney Impairment: Adult
There are no dosage adjustments provided in the manufacturer's labeling; however, dosage adjustment unlikely due to low systemic absorption.
Dosing: Hepatic Impairment: Adult
There are no dosage adjustments provided in the manufacturer's labeling; however, dosage adjustment unlikely due to low systemic absorption.
Dosing: Older Adult
Refer to adult dosing.
Adverse Reactions
There are no adverse reactions listed in the manufacturer's labeling.
Contraindications
Hypersensitivity to hydroxypropyl methylcellulose or any component of the formulation; in conjunction with hot laser treatment (Gonak, Goniosoft).
Warnings/Precautions
Other warnings/precautions:
• Appropriate use: Remove contact lenses prior to use. Do not use if solution changes color or becomes cloudy.
• Self-medication (OTC use): When used for self-medication, discontinue and contact a health care provider if eye pain, vision changes, continued redness, or eye irritation occur or if condition worsens or persists >72 hours.
Dosage Forms: US
Excipient information presented when available (limited, particularly for generics); consult specific product labeling. [DSC] = Discontinued product
Gel, Ophthalmic:
GenTeal Severe: 0.3% (10 g)
Vista Gel Dry Eye Relief: 0.3% (10 mL [DSC])
Solution, Intraocular:
OcuCoat Viscoadherent: 2% (1 mL [DSC])
Solution, Ophthalmic:
Alcon Tears: 0.5% (15 mL) [contains benzalkonium chloride]
Gonak: 2.5% (15 mL [DSC]) [contains benzalkonium chloride, edetate (edta) disodium]
Goniosoft: 2.5% (15 mL [DSC])
Goniotaire: 2.5% (15 mL)
Isopto Tears: 0.5% (15 mL [DSC]) [contains benzalkonium chloride]
Pure & Gentle Lubricant: 3 mg/mL (15 mL, 30 mL)
Vista Gonio Dry Eye Relief: 2.5% (15 mL) [contains benzalkonium chloride, edetate (edta) disodium]
Solution Prefilled Syringe, Ophthalmic [preservative free]:
ImproVue: 1.7% (2 mL)
Generic Equivalent Available: US
May be product dependent
Pricing: US
Gel (GenTeal Severe Ophthalmic)
0.3% (per gram): $0.86
Solution (Alcon Tears Ophthalmic)
0.5% (per mL): $2.24
Solution (Goniotaire Ophthalmic)
2.5% (per mL): $1.58
Solution (Pure & Gentle Lubricant Ophthalmic)
3 mg/mL (per mL): $0.56
Solution (Vista Gonio Dry Eye Relief Ophthalmic)
2.5% (per mL): $2.46
Solution Prefilled Syringe (ImproVue Ophthalmic)
1.7% (per mL): $14.50
Disclaimer: A representative AWP (Average Wholesale Price) price or price range is provided as reference price only. A range is provided when more than one manufacturer's AWP price is available and uses the low and high price reported by the manufacturers to determine the range. The pricing data should be used for benchmarking purposes only, and as such should not be used alone to set or adjudicate any prices for reimbursement or purchasing functions or considered to be an exact price for a single product and/or manufacturer. Medi-Span expressly disclaims all warranties of any kind or nature, whether express or implied, and assumes no liability with respect to accuracy of price or price range data published in its solutions. In no event shall Medi-Span be liable for special, indirect, incidental, or consequential damages arising from use of price or price range data. Pricing data is updated monthly.
Administration: Adult
Ophthalmic: For ophthalmic use only. Remove contact lenses before using. Wash hands thoroughly before administration; do not touch tip of container to eye or any surface; replace cap after use. Do not reuse single-use syringes.
Gonak, Goniosoft: Not for use in conjunction with hot laser treatment. If solution dries on optical surfaces, let stand in cool water before cleansing.
Use: Labeled Indications
Eye irritation: Temporary relief of discomfort due to minor irritations of the eye or from exposure to wind and sun; protection against further eye irritation; relief of dry eyes.
Gonioscopic examination aid (Gonak, Goniosoft): For professional use during gonioscopic examination.
Ophthalmic surgical aid (OcuCoat Viscoelastic): Ophthalmic surgical aid in anterior segment surgical procedures, including cataract extraction and intraocular lens implantation.
Medication Safety Issues
Sound-alike/look-alike issues:
Isopto Tears may be confused with Isoptin.
Metabolism/Transport Effects
None known.
Drug Interactions
There are no known significant interactions.
Brand Names: International
International Brand Names by CountryFor country code abbreviations (
show table)
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(AE) United Arab Emirates: Isopto Alkaline | Isopto Plain;
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(AR) Argentina: Aurovisc | Cool tears | Latlas tears | Lubrilag | Ocutears | Oftalook plus;
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(AT) Austria: Okuzell | Prosicca | Viscosan;
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(AU) Australia: Artelac | Genteal | In a wink moisturising | Methocel | Revive tears;
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(BD) Bangladesh: Genagel | Hyprogel | Hyprosol | Lubric | Ocugel | Optagel | Tearsol;
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(BE) Belgium: Artelac;
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(BG) Bulgaria: Artelac | Crystal Vision | Genteal;
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(BR) Brazil: Filmcel;
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(CH) Switzerland: Methocel;
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(CI) Côte d'Ivoire: Artelac;
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(CL) Chile: Aurosol | Genteal | Hiprocel | Luvis | Ophthacril;
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(CN) China: Isopto tears;
-
(CO) Colombia: Genteal | Hidroxipropilmetil celulosa | Hiprolub | Lagrimas artificiales | Lagrimpro | Ojoscalm | Ophthacril | Optialiv | Oq fil;
-
(DE) Germany: Artelac edo | Berberil EDO | Lacri vision | Okuzell | Sic ophtal n | Xailin hydrate;
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(DK) Denmark: Viskoese oejendraaber ophtha;
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(DO) Dominican Republic: Cool eyes | Lagrinox | Lubrigot;
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(EC) Ecuador: Akwa r | Humedbio | Lagrimas artificiales | Meticel ofteno;
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(EE) Estonia: Hypromeloza p | Hyprosan | Methocel;
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(EG) Egypt: Artelac ophtiole | Celoftal surgical | Genteal | Lasting tears | Optiguard | Tears guard;
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(ES) Spain: Artific;
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(FI) Finland: Artelac | Hyprosan | Isopto Alkaline;
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(GB) United Kingdom: Avizor lacrifresh aloe | Evolve everyday | Eyefill hd | Hiproviz | Hydromoor | Lumecare evolve | Mandanol | Moorvisc hpmc | Ocu lube | Pf drops hypromellose | Tear lac | Teardew | Xailin hydrate;
-
(HK) Hong Kong: Jemellose | Methocel;
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(HR) Croatia: Isopto tears;
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(ID) Indonesia: Braito tears;
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(IE) Ireland: Methocel | Moorvisc hpmc;
-
(IN) India: Aquatears | Arogel | Comoist | Extralube | Eyefil | Eyemist | Eyemist forte | Freshnac | Genteal | Hymelose | Hyprogel | Intavisc mv pf | Irimist | Lacrimist | Lacryl PF | Lub | Melose | Moisol | Moisol z | Optear | Optimoist | Ovs pfs | Oxana | Retentio | Tearsol | Viscotrust;
-
(JO) Jordan: Genteal | Hidrocil filac | Tears guard;
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(KE) Kenya: Aurosol | Aurovisc | Ivymoicell;
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(KR) Korea, Republic of: Hycell | Tear balance;
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(KW) Kuwait: Isopto tears;
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(LT) Lithuania: Methocel | Ocucoat | Ooculi;
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(LV) Latvia: Methocel | Ooculi;
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(MA) Morocco: Artelac;
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(MX) Mexico: Celulose grin | Devlyn | Exalum | Hipromelosa | Kiladel | Lubyfreshing | Luvistar | Meticel ofteno | Solutina lub;
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(MY) Malaysia: Cellugel | Eye glo moist | Eye Mo Moist | Genteal | Humalac b | I dew soothe | Lacri vision | Methocel;
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(NG) Nigeria: Ivymoicell eye drops | Melotears;
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(NL) Netherlands: Methocel | Pe ha glide;
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(NO) Norway: Artelac | Hyprosan | Methocel | Methocel specific;
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(PE) Peru: Eyevisc | Hidrotears | Humed | Humedbio | Lagrifat | Meticel ofteno | Unitears | Visualin | Visualip;
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(PH) Philippines: Artears | Aurovisc | Cool eyes | Equisine moist | Eye glo moist | Genteal | Ilube | Itearz | Opticul;
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(PK) Pakistan: Hicel | Hypomer | Lubrisol | Tearkool;
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(PL) Poland: Artelac | Methocel;
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(PR) Puerto Rico: Cellugel | Goniosoft | Goniosol | Isopto tears | Tearisol;
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(PT) Portugal: Hidrocil filac;
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(PY) Paraguay: Genteal | Latlas tears;
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(QA) Qatar: Oculac;
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(RO) Romania: Hypromel;
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(RU) Russian Federation: Artificial tear | Deflislez;
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(SE) Sweden: Hyprosan;
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(SG) Singapore: Artelac | Eye Mo Moist | Methocel;
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(SI) Slovenia: Artelac | Artelac UNO;
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(TH) Thailand: Aqua tear | Methocel | Miltear | Natear | Optal tears | Seeview sofs;
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(TN) Tunisia: Artelac;
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(TW) Taiwan: Methopt | Natural tears | Wu Fu Yes Eye;
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(UG) Uganda: Aurosol | Aurovisc;
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(UY) Uruguay: Alcon lagrimas ii;
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(VE) Venezuela, Bolivarian Republic of: Hidroxipropilmetilcelulosa | Lagricof | Lagrimpro | Lagrioftol;
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(VN) Viet Nam: Laci eye;
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(ZA) South Africa: Artelac moisture | Methocel | Spersatear | Viscotraan | Xailin hydrate;
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(ZM) Zambia: Ivymoicell | Moisol;
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(ZW) Zimbabwe: Moisol