Absolute |
Risk of infectious agent |
Detection of gastrointestinal pathogens in stool (including Clostridioides [formerly Clostridium] difficile) |
Known HIV, hepatitis B, C, or active syphilis infections |
Known exposure to HIV or viral hepatitis (within the previous 12 months) |
High-risk sexual behaviors |
Use of illicit drugs |
Tattoo or body piercing within six months |
Incarceration or history of incarceration |
Known current communicable disease (eg, upper respiratory tract infection) |
Risk factors for variant Creutzfeldt-Jakob disease |
Travel (within the last six months) to areas of the world where diarrheal illnesses are endemic or risk of traveler's diarrhea is high |
Known colonization with or risk factors for multi-drug resistant organisms in stool |
Gastrointestinal comorbidities |
History of inflammatory bowel disease |
History of IBS, idiopathic chronic constipation, or chronic diarrhea |
History of gastrointestinal malignancy or known polyposis |
Factors that can or do affect the composition of the intestinal microbiota |
Antibiotics within the preceding three months |
Major immunosuppressive medications (eg, calcineurin inhibitors, exogenous glucocorticoids, biological agents, etc) |
Systemic antineoplastic agents |
Additional recipient-specific considerations |
Recent ingestion of a potential allergen (eg, nuts) where recipient has a known allergy to this (these) agent(s) |
Relative exclusion criteria that might be appropriate to consider |
History of major gastrointestinal surgery (eg, gastric bypass) |
Metabolic syndrome |
Systemic autoimmunity (eg, multiple sclerosis, connective tissue disease) |
Atopic diseases including asthma and eczema, eosinophilic disorders of the gastrointestinal tract |
Chronic pain syndromes (eg, chronic fatigue syndrome, fibromyalgia) |
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