Radiologic features of TSC

(A-D) Contrast-enhanced abdominal CTs obtained in 1991 (A), 1998 (B), 2008 (C), and 2013 (D) in a male patient with TSC. Typical radial, striated, or wedge-shaped appearance of numerous small AMLs in 1991, with progressive enlargement over the following 22 years. Coil in the lower pole of the left kidney from embolization of a large pseudoaneurysm in 2010 (D).
(E) CT showing a fat-poor AML, containing an area of hemorrhage; histologic examination of the resected mass revealed it to be an epithelioid AML.
(F) CT showing a fat-containing AML within a polycystic kidney, a finding pathognomonic for TSC.
(G) CT of the abdomen in a female patient with TSC, illustrating perirenal lymphangiomatous cysts.
(H) Ultrasound showing a small (11.2 cm) hyperechoic kidney in a 52-year-old patient presenting with CKD stage 4; the kidneys contain some cysts but do not have the appearance of polycystic kidneys and do not contain AMLs.