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Diagnostic criteria for primary progressive aphasia

Diagnostic criteria for primary progressive aphasia
Inclusion: criteria 1-3 must be answered positively
  1. Most prominent clinical feature is difficulty with language
  2. These deficits are the principal cause of impaired daily living activities
  3. Aphasia should be the most prominent deficit at symptom onset and for the initial phases of the disease
Exclusion: criteria 1-4 must be answered negatively
  1. Pattern of deficits is better accounted for by other nondegenerative nervous system or medical disorders
  2. Cognitive disturbance is better accounted for by a psychiatric diagnosis
  3. Prominent initial episodic memory, visual memory, and visuoperceptual impairments
  4. Prominent, initial behavioral disturbance
PPA: primary progressive aphasia.
Reproduced with permission from: Gorno-Tempini ML, Hillis AE, Weintraub S, et al. Classification of primary progressive aphasia and its variants. Neurology 2011; 76:1006. DOI: 10.1212/WNL.0b013e31821103e6. Copyright © 2011 American Academy of Neurology. Unauthorized reproduction of this material is prohibited.
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