Selected risk factors associated with acquisition of Serratia infection during hospital outbreaks

Adult outbreaks^[1-3]

Receipt of contaminated medication

Indwelling device (central venous catheter, urinary catheter)

Endotracheal intubation

Longer hospital or intensive care unit stay

Antibiotic exposure prior to infection

Tube feeding

Parenteral nutrition

Medical comorbidities

Immune compromise

Neonatal outbreaks^[4,5]

Low birth weight

Maternal infection prior to delivery (eg, chorioamnionitis)

Longer hospital or intensive care unit stay

Antibiotic exposure prior to infection

Central venous catheter

Endotracheal intubation

References:

Mahlen SD. Serratia infections: from military experiments to current practice. Clin Microbiol Rev. 2011; 24(4):755-91.
De Boer MG, Brunsveld-Reinders AH, Salomons EM, Dijkshoorn L, Bernards AT, van den Berg PC, et al. Multifactorial origin of high incidence of Serratia marcescens in a cardio-thoracic ICU: analysis of risk factors and epidemiological characteristics. J Infect. 2008; 56(6):446-53.
Van der Sar-van der Brugge S, Arend SM, Bernards AT, Berbee GAM, Westendorp RGJ, Feuth JDM, et al. Risk factors for acquisition of Serratia marcescens in a surgical Intensive Care Unit. Journal of Hospital Infection. 1999; 41(4):291-9.
Buffet-Bataillon S, Rabier V, Betremieux P, Beuchee A, Bauer M, Pladys P, et al. Outbreak of Serratia marcescens in a neonatal intensive care unit: contaminated unmedicated liquid soap and risk factors. J Hosp Infect. 2009; 72(1):17-22.
Voelz A, Muller A, Gillen J, Le C, Dresbach T, Engelhart S, et al. Outbreaks of Serratia marcescens in neonatal and pediatric intensive care units: clinical aspects, risk factors and management. Int J Hyg Environ Health. 2010; 213(2):79-87.

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