NCI CTCAE v5.0 electrocardiogram QT corrected interval prolonged

Adverse event	Grade 1	Grade 2	Grade 3	Grade 4	Grade 5
Corrected QT interval prolongation on the electrocardiogram	Average QTc 450 to 480 milliseconds	Average QTc 481 to 500 milliseconds	Average QTc ≥501 milliseconds; >60 milliseconds change from baseline	Torsade de pointes; polymorphic ventricular tachycardia; signs/symptoms of serious arrhythmia

Prolongation of the corrected QT interval is a cardiac dysrhythmia characterized by an abnormally long corrected QT interval.

NCI CTCAE: National Cancer Institute Common Terminology Criteria for Adverse Events; QTc: corrected QT interval.

Reproduced from: Common Terminology Criteria for Adverse Events (CTCAE), Version 5.0, November 2017, National Institutes of Health, National Cancer Institute. Available at: https://ctep.cancer.gov/protocoldevelopment/electronic_applications/docs/CTCAE_v5_Quick_Reference_8.5x11.pdf (Accessed March 27, 2018).

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