NCI CTCAE v5.0 cystitis noninfective

Adverse event	Grade 1	Grade 2	Grade 3	Grade 4	Grade 5
Cystitis noninfective	Microscopic hematuria; minimal increase in frequency, urgency, dysuria, or nocturia; new onset of incontinence	Moderate hematuria; moderate increase in frequency, urgency, dysuria, nocturia, or incontinence; urinary catheter placement or bladder irrigation indicated; limiting instrumental activities of daily living	Gross hematuria; transfusion, intravenous medications, or hospitalization indicated; elective invasive intervention indicated	Life-threatening consequences; urgent invasive intervention indicated	Death

Noninfective cystitis is characterized by inflammation of the bladder that is not caused by an infection of the urinary tract.

NCI CTCAE: National Cancer Institute Common Terminology Criteria for Adverse Events.

Reproduced from: Common Terminology Criteria for Adverse Events (CTCAE), Version 5.0, November 2017, National Institutes of Health, National Cancer Institute. Available at: https://ctep.cancer.gov/protocoldevelopment/electronic_applications/docs/CTCAE_v5_Quick_Reference_8.5x11.pdf (Accessed March 27, 2018).

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