NCI CTCAE v5.0 glucose abnormalities

Adverse event	Grade 1	Grade 2	Grade 3	Grade 4	Grade 5
Hyperglycemia	Abnormal glucose above baseline with no medical intervention	Change in daily management from baseline for a diabetic; oral antiglycemic agent initiated; workup for diabetes	Insulin therapy initiated; hospitalization indicated	Life-threatening consequences; urgent intervention indicated	Death
Hypoglycemia	<LLN to 55 mg/dL; <LLN to 3 mmol/L	<55 to 40 mg/dL; <3.0 to 2.2 mmol/L	<40 to 30 mg/dL; <2.2 to 1.7 mmol/L	<30 mg/dL; <1.7 mmol/L; life-threatening consequences; seizures	Death

Hyperglycemia and hypoglycemia indicate an elevation or a reduction in blood sugar, respectively.

NCI CTCAE: National Cancer Institute Common Terminology Criteria for Adverse Events; LLN: lower limit of normal.

Reproduced from: Common Terminology Criteria for Adverse Events (CTCAE), Version 5.0, November 2017, National Institutes of Health, National Cancer Institute. Available at: https://ctep.cancer.gov/protocoldevelopment/electronic_applications/docs/CTCAE_v5_Quick_Reference_8.5x11.pdf (Accessed March 27, 2018).

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