Version July 2025
| Insulin | Trade name in the United States | Protamine (yes/no) | Other | Availability outside of the United States |
| Rapid acting (duration 2 to 4 hours) | ||||
| Aspart | NovoLog | No | Metacresol, glycerin, phenol, zinc | Yes (NovoRapid) |
| Lispro | Humalog | No | Metacresol, glycerin, zinc | Yes (Humalog, Liprolog) |
| Glulisine | Apidra | No | Metacresol, tromethamine, polysorbate 20 | Yes (Apidra) |
| Short acting (duration 5 to 8 hours) | ||||
| Regular | Humulin R, Novolin R, Novolin R ReliOn | No | Metacresol, glycerin, zinc | Yes (Actraphane, Actrapid Human, Humulin, others) |
| Intermediate acting (duration 14 to 24 hours) | ||||
| NPH (human insulin isophane suspension) | Humulin N, Novolin N, Novolin N ReliOn | Yes | Metacresol, glycerin, phenol, zinc | Yes |
| U-500 concentrated | Humulin R Regular U-500 | No | Metacresol, glycerin, zinc | Yes (Humulin R regular U-500) |
| Intermediate-acting mixtures (duration 14 to 24 hours with a more rapid peak) | ||||
| 75% lispro protamine and 25% lispro | Humalog Mix 75/25 and 50/50 | Yes | Metacresol, glycerin, phenol, zinc | Yes (Humalog Mix, Humalog Mix 25, Humalog NPL) |
| 70% aspart protamine and 30% aspart | NovoLog Mix 70/30 | Yes | Metacresol, glycerin, phenol, zinc | Yes (NovoMix 30) |
| NPH and regular | Humulin Mix 70/30 and Novolin Mix 70/30 | Yes | Metacresol, dibasic sodium phosphate, glycerol, phenol, protamine sulfate, zinc | Yes (Insulatard, Huminsulin Basal) |
| Intermediate to long acting (duration 6 to 24 hours, dose dependent) | ||||
| Detemir | Levemir | No | Metacresol, glycerin, phenol, zinc | Yes (Levemir) |
| Long acting (duration 20 to >24 hours) | ||||
| Glargine | Lantus, Basaglar, Toujeo, Semglee | No | Metacresol, zinc, glycerol | Yes (Lantus,Toujeo, Abasaglar) |
| Degludec | Tresiba | No | Metacresol, glycerol, phenol, zinc acetate, hydrochloric acid, sodium hydroxide | Yes (Tresiba) |
NPH: neutral protamine Hagedorn; DNA: deoxyribonucleic acid.
* According to product information in the United States. Check local prescribing information. Glycerol is an international nonproprietary name for glycerin (United States name). Metacresol (m-cresol) is a phenol-type preservative. Products are pH adjusted.