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Association of CKD risk factors with GFR depends upon how GFR is assessed

Association of CKD risk factors with GFR depends upon how GFR is assessed
The association of CKD risk factors with percentage decrease in GFR (↓ GFR) by each method (mGFR, eGFRCr, eGFRCr-CysC, and eGFRCysC). The * identifies p<0.05 for eGFR compared to mGFR. Risk factor associations with mGFR were more similar to those with eGFRCr than with eGFRCr-CysC or eGFRCysC. The one exception was 24-hour urine creatinine where eGFRCysC was more similar to the same association with mGFR.
Reprinted by permission from Macmillan Publishers Ltd: Kidney International. Rule AD, Bailey KR, Lieske JC, et al. Estimating the glomerular filtration rate from serum creatinine is better than from cystatin C for evaluating risk factors associated with chronic kidney disease. Kidney Int 2013; 83:1169. Copyright © 2013. www.nature.com/ki.
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