Adjusted hazard ratio for all-cause mortality

(A) Association of estimated GFR with all-cause mortality among individuals aged 18 to 54 years (reference group: >105 mL/min/1.73 m²).
(B) Association of estimated GFR with all-cause mortality among individuals 75 years and older (reference group: 75 to 89 mL/min/1.73 m²).
Adjusted hazard ratios for all-cause mortality in individuals without albuminuria based on pooled estimates from 33 general population cohorts. Low risk is a serum creatinine-based estimated GFR of >75 mL/min/1.73 m² in younger adults (18 to 54 years, top panel) and an estimated GFR of 45 to 104 mL/min/1.73 m² in older adults (>75 years, bottom panel).