Pediatric donor management goals

Hemodynamic support	Blood pressure (mmHg)
Normalization of blood pressure Systolic blood pressure appropriate for age NOTE: Lower systolic blood pressures may be acceptable if biomarkers such as lactate are normal CVP <12 (if measured) Minimize vasoactive and inotropic support Normal serum lactate		Systolic*	Diastolic
	Neonate	60 to 90	35 to 60
	Infants (6 months)	80 to 95	50 to 65
	Toddler (2 years)	85 to 100	50 to 65
	School age (7 years)	90 to 115	60 to 70
	Adolescent (15 years)	110 to 130	65 to 80
Oxygenation and ventilation	Fluids and electrolytes
Maintain PaO₂ >100 mmHg FiO₂ 0.40 Normalize PaCO₂ 35 to 45 mmHg Arterial pH 7.30 to 7.45 Tidal volumes 8 to 10 cc/kg PEEP 5 cm H₂O	Serum Na⁺ 130 to 150 mEq/L Serum K⁺ 3 to 5 mEq/L Serum glucose 60 to 150 mg/dL Ionized Ca⁺⁺ (if measured) 0.8 to 1.2 mmol/L
Thermal regulation
Core body temperature 36 to 38°C

CVP: central venous pressure; FiO₂: fraction of inspired oxygen; PaCO₂: arterial carbon dioxide tension; PaO₂: arterial oxygen tension; PEEP: positive end-expiratory pressure.

* Normal systolic blood pressure = 80 + (Age in years × 2).

Graphic 91611 Version 4.0

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Pediatric donor management goals