Version June 2024
| Generic name | US brand name | Dry mouth, blurred vision, trouble urinating, constipation, dizziness | Drowsiness | Trouble sleeping, jitteriness | Nausea, vomiting, diarrhea | Weight gain | Sexual problems |
| Tricyclic and tetracyclic antidepressants ("TCAs") | |||||||
| Amitriptyline | Elavil | High | High | None | Very low | High | Moderate to high |
| Amoxapine | Asendin (only sold as generic in US) | Low | Low | Low | None | Low | Unknown |
| Clomipramine | Anafranil | High | High | Very low | Very low | High | High |
| Desipramine | Norpramin | Very low | High | Very low | None | Very low | Unknown |
| Doxepin | Silenor, Sinequan | Moderate | Moderate | None | None | High | Moderate |
| Imipramine | Tofranil | Moderate | Moderate | Very low | Very low | High | Moderate |
| Maprotiline | Ludiomil (only sold as generic in US) | Low | Moderate | None | None | Low | Unknown |
| Nortriptyline | Pamelor | Low | Low | None | None | Very low | Unknown |
| Protriptyline | Vivactil (only sold as generic in US) | Low | Very low | Very low | Very low | Very low | Moderate to high |
| Trimipramine | Surmontil | High | High | Very low | None | High | Unknown |
| Monoamine oxidase inhibitors | |||||||
| Isocarboxazid | Marplan | Very low | Very low | Low | Very low | Very low | High |
| Phenelzine | Nardil | Very low | Low | Very low | Very low | Low | High |
| Selegiline | Eldepryl, Emsam, others | Very low | None | Very low | None | None | None |
| Tranylcypromine | Parnate | Very low | Very low | Low | Very low | Very low | High |
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