Version May 2024
Surgical aid: Intraocular: Inject (using a 27-gauge cannula) into anterior chamber during surgery; may be injected into the anterior chamber prior to or following removal of crystalline lens. See directions for use in manufacturer's labeling.
There are no dosage adjustments provided in the manufacturer’s labeling.
There are no dosage adjustments provided in the manufacturer’s labeling.
Refer to adult dosing.
There are no adverse reactions listed in the manufacturer's labeling.
Postmarketing: Ophthalmic: Increased intraocular pressure (Rainer 2001)
There are no contraindications listed in the manufacturer’s labeling.
Concerns related to adverse effects:
• Hypersensitivity: Potential risk of hypersensitivity may exist with the use of any biological material.
Other warnings/precautions:
• Appropriate use: For intraocular use only; serious eye injury may occur if proper assembly instructions of cannula and cannula locking ring are not followed or alternate cannula is used.
Excipient information presented when available (limited, particularly for generics); consult specific product labeling.
Injection, solution, intraocular:
DisCoVisc: Sodium chondroitin sulfate ≤4% and sodium hyaluronate ≤1.7% (1 mL) [provided in a kit which also contains 27-gauge cannula and cannula locking ring]
Viscoat: Sodium chondroitin sulfate ≤4% and sodium hyaluronate ≤3% (0.5 mL, 0.75 mL) [packaged with 27-gauge cannula and cannula locking ring]
No
Consult specific product instructions on preparing intraocular device for use and administration by physician during surgery. For intraocular use only; do not reuse cannulas. May inject in the anterior segment of the eye prior to or following removal of the crystalline lens. Instillation prior to lens removal provides additional protection to corneal endothelium, protecting it from possible damage arising from surgical instrumentation. May also be used to coat intraocular lens and tips of surgical instruments prior to implantation surgery. May inject additional solution during anterior segment surgery to fully maintain the solution lost during surgery. At the end of surgery, remove solution by thoroughly irrigating and aspirating with a sterile irrigating solution (eg, balanced salt solution).
Surgical aid: An ophthalmic surgical aid in anterior segment procedures, including cataract extraction and intraocular lens implantation
None known.
There are no known significant interactions.
Intraocular pressure at baseline and after procedure
Ophthalmic viscosurgical device which modulates the interactions between adjacent tissues by space creation, tissue stabilization, balancing pressure, and providing protection of the corneal endothelial cells during surgery (Arshinoff 2013).
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