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Pre-exposure evaluation for health-care personnel previously vaccinated with complete, ≥3-dose HepB vaccine series who have not had postvaccination serologic testing

Pre-exposure evaluation for health-care personnel previously vaccinated with complete, ≥3-dose HepB vaccine series who have not had postvaccination serologic testing
* Should be performed 1-2 months after the last dose of vaccine using a quantitative method that allows detection of the protective concentration of anti-HBs. (≥10 mIU/mL) (eg, enzyme-linked immunosorbent assay [ELISA]).
A nonresponder is defined as a person with anti-HBs <10 mIU/mL after ≥6 doses of HepB vaccine. Persons who do not have a protective concentration of anti-HBs after revaccination should be tested for HBsAg. If positive, the person should receive appropriate management or vaccination.
Reproduced from: CDC Guidance for Evaluating Health-Care Personnel for Hepatitis B Virus Protection and for Administering Postexposure Management. MMWR Recomm Rep 2013; 62:1.
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