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Criteria for the Kidney Disease Improving Global Outcomes (KDIGO) acute kidney injury for children

Criteria for the Kidney Disease Improving Global Outcomes (KDIGO) acute kidney injury for children
Stage Serum creatinine (SCr) Urine output
1 Increase to 1.5 to 1.9 times baseline, OR increase of ≥0.3 mg/dL (≥26.5 mcmol/L) <0.5 mL/kg per hour for 6 to 12 hours
2 Increase to 2 to 2.9 times baseline <0.5 mL/kg per hour for ≥12 hours
3

Increase greater than 3 times baseline, OR

SCr ≥4 mg/dL (≥353.6 mcmol/L), OR

Initiation of renal replacement therapy, OR

eGFR <35 mL/min per 1.73 m2 (<18 years)

<0.3 mL/kg per hour for ≥24 hours, OR

Anuria for ≥12 hours
The time frames for the increases in serum creatinine are:
  • Increase of SCr ≥0.3 mg/dL (≥26.5 mcmol/L) within 48 hours
  • Increase in SCr >1.5 times the baseline within the prior seven days
eGFR: estimated glomerular filtration rate.
Reprinted by permission from Macmillan Publishers Ltd: Kidney International Supplements. Summary of Recommendation Statements. Kidney Disease: Improving Global Outcomes (KDIGO) Acute Kidney Injury Work Group. KDIGO Clinical Practice Guideline for Acute Kidney Injury. Kidney Int Suppl 2012; 2:8. Copyright © 2012. www.nature.com/kisup.
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