Unactivated prothrombin complex concentrates (PCCs) | |
4 factor:*
| Contain inactive forms of 4 factors: Factors II, VII, IX, and X Also contain heparin |
3 factor:
| Contains inactive forms of 3 factors: Factors II, IX, and X Contains little or no factor VII Does not contain heparin |
Activated prothrombin complex concentrate (aPCC) | |
4 factor:
| Contains 4 factors: Factors II, VII, IX, and X. Of these, only factor VII is mostly the activated form¶ Does not contain heparin |
FEIBA: factor eight inhibitor bypassing activity; PCC: prothrombin complex concentrate; US: United States.
* Kcentra is available as Beriplex or Confidex in other countries. Balfaxar is available as Octaplex in other countries.
¶ Single-factor recombinant activated factor VII (rFVIIa) products are also available.