High-risk group* | Hib vaccine guidance |
Patients aged <12 months | Follow routine Hib vaccination recommendations |
Patients aged 12 to 59 months | If unimmunized or received 0 or 1 dose before age 12 months: 2 doses, 8 weeks apart |
If received ≥2 doses before age 12 months: 1 dose, 8 weeks after last dose | |
If completed a primary series and received a booster dose at age ≥12 months: No additional doses | |
Patients aged <60 months undergoing chemotherapy or radiation therapy¶ | If routine Hib doses administered ≥14 days before starting therapy: Revaccination not required |
If dose administered within 14 days of starting therapy or given during therapy: Repeat doses starting at least 3 months following therapy completion | |
Patients aged ≥15 months undergoing elective splenectomy | If unimmunizedΔ: 1 dose prior to procedure◊ |
Asplenic patients aged >59 months and adults | If unimmunizedΔ: 1 dose |
HIV-infected children aged ≥60 months | If unimmunizedΔ: 1 dose |
HIV-infected adults | Hib vaccination is not recommended |
Recipients of hematopoietic stem cell transplant, all ages | Regardless of Hib vaccination history: 3 doses (at least 4 weeks apart) beginning 6 to 12 months after transplant |
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