Version June 2024
| Medicine name | How used | How it works | Comments |
| Buprenorphine combined with naloxone (brand names: Suboxone, Zubsolv) | Suboxone – Film that melts under your tongue (lime flavor). Zubsolv – Tablet that melts under your tongue (menthol flavor). | This medicine eases drug cravings and helps prevent withdrawal symptoms. It also blocks the effects of opioids, so you cannot get high even if you use drugs. | May cause burning or tingling under the tongue. Contains naloxone, which prevents misuse of the drug. |
| Buprenorphine (brand names: Brixadi, Sublocade) | A shot you can get once a week or once a month. | This medicine eases drug cravings and helps prevent withdrawal symptoms. It also blocks the effects of opioids, so you cannot get high even if you use drugs. | The implant or shot can be helpful for people who might stop taking a daily drug. |
| Methadone (brand names: Dolophine, Methadose) | Tablet or liquid that you swallow. Dissolving tablet is added to fruit juice or water before swallowing. | This medicine eases drug cravings and helps prevent withdrawal symptoms. It also makes it less likely that you can get high. | People taking methadone must go to a clinic every day or every few days to get their medicine. This medicine comes in different strength pills and liquids. Taking too much can be dangerous. Know what the medicine looks like and what dose you are supposed to take. |
| Naltrexone (brand names: ReVia, Vivitrol) | Pill that you swallow or shot that you get each month. | This medicine blocks the effects of opioids, so you cannot get high even if you use drugs. It helps people who have completely stopped using drugs to stay off of them. | Naltrexone can also help reduce cravings for alcohol. It should not be started until the person has been free of opioids for a while. |
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