CDC surveillance case definition HIV infection stage based on age-specific CD4+ T-lymphocyte count or CD4+ T-lymphocyte percentage of total lymphocytes

Stage	Age at time of CD4+ T-lymphocyte test*
	<1 year		1 to 5 years		≥6 years
	Cells/microL	Percent	Cells/microL	Percent	Cells/microL	Percent
0^¶	NA	NA	NA	NA	NA	NA
1	≥1500	≥34	≥1000	≥30	≥500	≥26
2	750 to 1499	23 to 33	500 to 999	22 to 29	200 to 499	14 to 25
3 (AIDS)^Δ	<750	<26	<500	<22	<200	<14
Unknown^◊	NA	NA	NA	NA	NA	NA

CDC: Centers for Disease Control and Prevention; NA: not applicable; AIDS: acquired immunodeficiency syndrome.
* The CD4+ T-lymphocyte count takes precedence over the CD4 T-lymphocyte percentage; the percentage is considered only if the count is missing.
¶ Stage 0 represents early infection and is defined by a negative or indeterminate HIV test within 180 days before the first confirmed positive HIV test. If the criteria for stage 0 are met, the stage is 0 regardless of criteria for other stages (CD4 T-lymphocyte test results and opportunistic illness diagnoses).
Δ If the criteria for stage 0 are not met and a stage 3-defining opportunistic illness has been diagnosed, then the stage is 3 regardless of CD4 T-lymphocyte test results.
◊ If the criteria for stage 0 are not met and information on the above criteria for other stages is missing, then the stage is classified as unknown.

Adapted from: Selik RM, Mokotoff ED, Branson B, et al. Revised Surveillance Case Definition for HIV Infection - United States, 2014. MMWR Recomm Rep 2014; 63:1.

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CDC surveillance case definition HIV infection stage based on age-specific CD4+ T-lymphocyte count or CD4+ T-lymphocyte percentage of total lymphocytes