Class | Class 0 | Class 1 | Class 2 | Class 3 | Class 4 | ||||||||||||||||
Whole person impairment rating (%) | 0 | 2 to 10 | 11 to 23 | 24 to 40 | 45 to 65 | ||||||||||||||||
Severity grade | |||||||||||||||||||||
Percent impairment | 2 | 4 | 6 | 8 | 10 | 11 | 14 | 17 | 20 | 23 | 24 | 28 | 32 | 36 | 40 | 45 | 50 | 55 | 60 | 65 | |
Grade | A | B | C | D | E | A | B | C | D | E | A | B | C | D | E | A | B | C | D | E | |
Minimal | Mild | Moderate | Severe | ||||||||||||||||||
Clinical parameters (minimum medication need, frequency of attacks, etc) | No medication required | Occasional bronchodilator use (not daily use) | Daily low-dose inhaled glucocorticoid (<500 mcg per day of beclomethasone or equivalent) | Daily medium or high-dose inhaled glucocorticoids (500 to 1000 mcg of beclomethasone or equivalent per day) and/or short periods of systemic glucocorticoids and a long acting bronchodilator Daily use of glucocorticoids, systemic and inhaled, and daily use of maximum bronchodilators | Asthma not controlled by treatment | ||||||||||||||||
Maximum postbronchodilator FEV1 percentage predicted*¶ | >80 | 70 to 80 | 60 to 69 | 50 to 59 | <50 | ||||||||||||||||
Objective tests for degree of airway hyperresponsiveness | |||||||||||||||||||||
PC20 mg/mL* | 6 to 8 | 3 to 5 | >0.5 to <3 | 0.25 to 0.5 | 0.125 to 0.24 |
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