(A) Proliferative verrucous leukoplakia of the gingiva with flat and exophytic appearance.
(B) On histologic examination, the lesion reveals markedly hyperplastic and papillomatous squamous proliferation. Note the extensive keratinization and the thin band of subepithelial chronic inflammatory cells.
Reproduced with permission from: Gillenwater AM, Vigneswaran N, Fatani H, et al. Proliferative verrucous leukoplakia (PVL): a review of an elusive pathologic entity! Adv Anat Pathol 2013; 20:416. DOI:
10.1097/PAP.0b013e3182a92df1. Copyright © 2013 Lippincott Williams & Wilkins. Unauthorized reproduction of this material is prohibited.