Version July 2025
Skin irritation: Topical:
Cream: Apply to affected area as needed or as directed.
Scalp solution: Apply directly to scalp as needed or as directed.
Soak: Soak affected area in solution for 15 to 30 minutes as needed; may repeat 3 times daily or as directed.
Wet dressing/compress: Soak a clean, soft cloth in solution and apply loosely to affected area for 15 to 30 minutes; may repeat as needed or as directed.
There are no dosage adjustments provided in the manufacturer’s labeling. However, dosage adjustment unlikely due to low systemic absorption.
There are no dosage adjustments provided in the manufacturer’s labeling. However, dosage adjustment unlikely due to low systemic absorption.
Refer to adult dosing.
(For additional information see "Aluminum acetate: Pediatric drug information")
Skin irritation: Children and Adolescents: Topical:
Soak: Soak the affected area in solution for 15 to 30 minutes as needed; may repeat 3 times daily or as directed.
Wet dressings/compress: Soak a clean, soft cloth in solution and apply loosely to affected area for 15 to 30 minutes; may repeat as needed for 4 to 8 hours or as directed.
There are no dosage adjustments provided in the manufacturer’s labeling.
There are no dosage adjustments provided in the manufacturer’s labeling.
The following adverse drug reactions and incidences are derived from product labeling unless otherwise specified. Frequency not defined.
1% to 10%: Local: Local irritation
Other warnings/precautions:
• Appropriate use: For external use only; do not cover the treated area with plastic (wet dressing/compress). Avoid contact with eyes. Discontinue use if irritation occurs, condition worsens, or if symptoms persist more than 7 days; consult health care provider if irritation or sensitivity increases.
Excipient information presented when available (limited, particularly for generics); consult specific product labeling. [DSC] = Discontinued product
Cream, External, as acetate:
Dermeleve Advanced Formula: 0.2% (30 g [DSC], 60 g, 120 g) [steroid free; contains cetyl alcohol, edetate (edta) disodium]
Packet, External:
Astringent: (12 ea)
Boro-Packs: Aluminum sulfate 49% and calcium acetate 51% per packet (14 ea, 100 ea)
Domeboro: (12 ea)
Generic: Aluminum sulfate tetradecahydrate 1347 mg and calcium acetate monohydrate 952 mg per packet (1 ea [DSC], 12 ea [DSC])
Solution, External:
Dermeleve Anti-Itch Scalp: 0.2% (89 mL) [fragrance free, steroid free; contains edetate (edta) disodium, polysorbate 80]
Generic: (480 mL)
May be product dependent
Cream (Dermeleve Advanced Formula External)
0.2% (per gram): $0.50
Solution (Dermeleve Anti-Itch Scalp External)
0.2% (per mL): $0.34
Disclaimer: A representative AWP (Average Wholesale Price) price or price range is provided as reference price only. A range is provided when more than one manufacturer's AWP price is available and uses the low and high price reported by the manufacturers to determine the range. The pricing data should be used for benchmarking purposes only, and as such should not be used alone to set or adjudicate any prices for reimbursement or purchasing functions or considered to be an exact price for a single product and/or manufacturer. Medi-Span expressly disclaims all warranties of any kind or nature, whether express or implied, and assumes no liability with respect to accuracy of price or price range data published in its solutions. In no event shall Medi-Span be liable for special, indirect, incidental, or consequential damages arising from use of price or price range data. Pricing data is updated monthly.
Topical: For external use only; avoid contact with eyes. Do not apply to open wounds.
Scalp solution: Apply at first sign of itching; apply to dry hair and rub in if needed.
Wet dressing/compress: Dissolve powder prior to use. Soak a clean, soft cloth in the solution. Apply cloth loosely to affected area for 15 to 30 minutes. Do not cover the treated area with plastic (wet dressing/compress); extended soaking may overdry in some skin conditions. Discard solution after each use (when used for soak/wet dressing/compress).
Topical: Keep away from eyes; for external use only. Discard solution after each use.
When used as a compress or wet dressing, soak a clean soft cloth in the solution. Apply cloth loosely to affected area for 15 to 30 minutes. Do not occlude dressing to prevent evaporation. Do not allow dressing to dry out.
Skin irritation: Temporary relief of minor skin irritations due to poison ivy, oak, or sumac; itching; insect bites; athlete's foot; minor burns; scalp itch; and rashes caused by soaps, detergents, cosmetics, or jewelry.
None known.
There are no known significant interactions.
It is not known if topically administered aluminum acetate is excreted in breast milk.
