Relationship between body surface area (BSA) and drug clearance for six conventional chemotherapy agents

For irinotecan, apparent clearance corresponding to SN-38 was considered. R² values indicate the contribution of BSA to the inter-individual variability in clearance.

Reprinted by permission from Macmillan Publishers Ltd on behalf of Cancer Research UK: British Journal of Cancer. Chatelut E, White-Koning ML, Mathijssen RH, et al. Dose banding as an alternative to body surface area-based dosing of chemotherapeutic agents. Br J Cancer 2012; 107:1100. Copyright © 2012. www.nature.com/bjc.

Graphic 96665 Version 1.0

آیا می خواهید مدیلیب را به صفحه اصلی خود اضافه کنید؟