Muscle biopsy showing amyloid myopathy

Frozen sections of the deltoid muscle
(A) Trichrome stain shows a necrotic muscle fiber.
(B) Congo red stain shows extensive amyloid deposition in a perimysial blood vessel wall that is intensely red when viewed under rhodamine optics (C).

From: Ghosh PS, Thaera GM, Tracy JA. Teaching neuroimages: dyspnea as a presenting manifestation of amyloid myopathy. Neurology 2013; 81:e184. DOI: 10.1212/01.wnl.0000437300.51312.9e. Reproduced with permission from Lippincott Williams & Wilkins. Copyright © 2013 American Academy of Neurology. Unauthorized reproduction of this material is prohibited.

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Muscle biopsy showing amyloid myopathy