ﺑﺎﺯﮔﺸﺖ ﺑﻪ ﺻﻔﺤﻪ ﻗﺒﻠﯽ
خرید پکیج
تعداد آیتم قابل مشاهده باقیمانده : 3 مورد
نسخه الکترونیک
medimedia.ir

Bacitracin (topical): Pediatric drug information

Bacitracin (topical): Pediatric drug information
2024© UpToDate, Inc. and its affiliates and/or licensors. All Rights Reserved.
For additional information see "Bacitracin (topical): Drug information" and "Bacitracin (topical): Patient drug information"

For abbreviations, symbols, and age group definitions show table
Brand Names: US
  • FT Antibiotic [OTC]
Therapeutic Category
  • Antibiotic, Topical
Dosing: Pediatric
Prevention of infection

Prevention of infection: Infants, Children, and Adolescents: Topical: Apply small amount 1 to 3 times daily; duration of therapy >7 days is not recommended, unless directed by health care provider. Note: Do not use in the eyes or over large areas of the body.

Dosing: Adult

(For additional information see "Bacitracin (topical): Drug information")

Prevention of infection

Prevention of infection: Topical: Apply 1 to 3 times daily.

Adverse Reactions

The following adverse drug reactions and incidences are derived from product labeling unless otherwise specified.

Postmarketing and/or case reports: Anaphylaxis (Elsner 1990; Farley 1995)

Contraindications

Hypersensitivity to bacitracin or any component of the formulation

Warnings/Precautions

Concerns related to adverse effects:

• Allergic reaction: Stop use and consult health care provider if allergic reaction or rash develops.

• Anaphylaxis: Use with caution in patients who have been previously exposed to bacitracin; anaphylactic reactions have occurred on repeat exposure (Elsner, 1990; Farley, 1995).

Other warnings/precautions:

• Topical anti-infective (self-medication, OTC use): Use longer than 1 week is not recommended unless directed by prescriber. Do not use in eyes or over large areas of the body. Seek advice from health care provider prior to use for deep puncture wounds, bites, or serious burns, or if condition lasts longer than 1 week.

Dosage Forms: US

Excipient information presented when available (limited, particularly for generics); consult specific product labeling.

Ointment, External, as zinc [strength expressed as base]:

FT Antibiotic: 500 units/g (28.4 g)

Generic: 500 units/g (1 ea, 144 ea, 1 g, 14 g, 14.2 g, 15 g, 28 g, 28.35 g, 28.4 g, 30 g, 425 g, 453.9 g)

Generic Equivalent Available: US

Yes

Pricing: US

Ointment (Bacitracin External)

500 units/g (per gram): $0.08 - $0.12

500 units/g (per each): $0.14 - $0.23

Ointment (Bacitracin Zinc External)

500 units/g (per gram): $0.05 - $0.18

Disclaimer: A representative AWP (Average Wholesale Price) price or price range is provided as reference price only. A range is provided when more than one manufacturer's AWP price is available and uses the low and high price reported by the manufacturers to determine the range. The pricing data should be used for benchmarking purposes only, and as such should not be used alone to set or adjudicate any prices for reimbursement or purchasing functions or considered to be an exact price for a single product and/or manufacturer. Medi-Span expressly disclaims all warranties of any kind or nature, whether express or implied, and assumes no liability with respect to accuracy of price or price range data published in its solutions. In no event shall Medi-Span be liable for special, indirect, incidental, or consequential damages arising from use of price or price range data. Pricing data is updated monthly.

Administration: Pediatric

For external topical use only. Clean the affected area. Apply a small amount of product (an amount equal to the surface area of the tip of a finger); may cover with sterile bandage.

Administration: Adult

Clean the affected area prior to use. Apply a small amount of product (an amount equal to the surface area of the tip of a finger); may cover with sterile bandage.

Storage/Stability

Topical ointment (OTC): Store at 15°C to 30°C (59°F to 86°F).

Use

Prevention of infection in minor cuts, scrapes, or burns (FDA approved in pediatric patients [age not specified] and adults).

Medication Safety Issues
Sound-alike/look-alike issues:

Bacitracin may be confused with Bactrim, Bactroban

Metabolism/Transport Effects

None known.

Drug Interactions

Note: Interacting drugs may not be individually listed below if they are part of a group interaction (eg, individual drugs within “CYP3A4 Inducers [Strong]” are NOT listed). For a complete list of drug interactions by individual drug name and detailed management recommendations, use the drug interactions program

There are no known significant interactions.

Pregnancy Considerations

Although large studies have not been conducted, absorption is limited following topical application; use during pregnancy has not been associated with an increased risk of adverse fetal events (Leachman, 2006; Murase, 2014).

Mechanism of Action

Inhibits bacterial cell wall synthesis by preventing transfer of mucopeptides into the growing cell wall

Pharmacokinetics (Adult Data Unless Noted)

Absorption: Poor from mucous membranes and intact or denuded skin

  1. Advanced First Aid Bacitracin [prescribing information]. Baltimore, MD: Advanced First Aid, Inc; October 2016.
  2. Bacitracin ointment [prescribing information]. Huntsville, AL: Qualitest Pharmaceuticals; June 2008.
  3. Bacitracin ointment [prescribing information]. Melville, NY: Fougera Pharmaceuticals Inc; September 2011.
  4. Bacitracin ointment [prescribing information]. Livonia, MI: Major Pharmaceuticals; January 2020
  5. Elsner P, Pevny I, Burg G. Anaphylaxis induced by topically applied bacitracin. Am J Contact Dermat. 1990;1(3):162-164.
  6. Farley M, Pak H, Carregal V, Engler R, James W. Anaphylaxis to topically applied bacitracin. Am J Contact Dermat. 1995;6(1):28-31.
  7. Leachman SA, Reed BR. The use of dermatologic drugs in pregnancy and lactation. Dermatol Clin. 2006;24(2):167-197. [PubMed 16677965]
  8. Murase JE, Heller MM, Butler DC. Safety of dermatologic medications in pregnancy and lactation: part I. Pregnancy. J Am Acad Dermatol. 2014;70(3):1-14. [PubMed 24528911]
Topic 97144 Version 240.0

آیا می خواهید مدیلیب را به صفحه اصلی خود اضافه کنید؟