(A) Solid aggregates in the dermis (H&E 20x).
(B) Aggregates with follicular differentiation. Note the fibrous stroma (H&E 100x).
(C) Aggregates composed of germinative cells, matrical cells, and cells with inner sheath differentiation (H&E 400x).
(D) Cells with eosinophilic trichohyalin granules and associated blue-gray corneocytes, indicating inner sheath differentiation. Rudimentary papilla and inner sheath differentiation was evident (H&E 200x).
From: Shan SJ, Guo Y. Panfolliculoma and histopathologic variants: a study of 19 cases. Am J Dermatopathol 2014; 36:965. DOI:
10.1097/DAD.0000000000000108. Reproduced with permission from Lippincott Williams & Wilkins. Copyright © 2008 International Society of Dermatopathology. Unauthorized reproduction of this material is prohibited.
