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خرید پکیج
تعداد آیتم قابل مشاهده باقیمانده : 3 مورد
نسخه الکترونیک
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Outcomes for older women with newly diagnosed ovarian cancer

Outcomes for older women with newly diagnosed ovarian cancer
Author Age Number of patients PFS (months) OS Postoperative mortality Postoperative complications Primary surgery NACT selected
Marchetti, 1993 ≥65 years 29 NA 19.2 months 3 (10.3%) NA 28 (96.6%) 1 (3.4%)
Susini, 1999 ≥70 years 51 NA NA NA NA 51 (100%) Study exclusion
Cloven, 1999 ≥80 years 18 NA 6 months 2 (11.1%)
  • Cardiac: 7 (39%)
  • Sepsis: 3 (16.7%)
  • Pneumonia: 1 (5.6%)
16 (88.9%) 3 (16.7%)
Bruchim, 2002 ≥70 years 46 NA NA 2 (4.3%) NA 25 (54.3%) 13 (43.3%)
Wright, 2004 ≥70 years 46 NA NA 0
  • ICU admission: 20%
  • Infection: 8%
  • Delirium: 5%
  • Wound: 3%
  • Ileus: 2%
  • Arrhythmia: 2%
  • VTE: 1%
46 (100%) Study exclusion
Uyar, 2005 ≥70 years 131 NA

70 to 79 years: 52 months

≥80 years: 36 months

p = 0.07		 NA
  • Overall: 23%
105 (80%) 26 (20%)
Alphs, 2006 ≥75 years 78 NA 19 months 7 (9%)
  • Wound infection: 13 (16.7%)
  • Ileus: 5 (6.4%)
78 (100%) Study exclusion
Moore, 2008 ≥80 years 85 NA

1° surgery: two-year survival 51%

1° chemo: Two-year survival 27%		 9 (13%)
  • Cardiac: 17%
  • Pulmonary: 26%
  • GI: 22%
  • Heme/infectious: 62%
  • Mental status: 10%
  • Surgical site: 23%
68 (80%) 17 (20%)
Moore, 2009 ≥80 years 39 NA NA NA NA 39 (100%) Study exclusion
McLean, 2010 ≥80 years 34 NA 24 months 0
  • Ileus: 29.4%
  • Pneumonia: 6.1%
  • Wound infection: 3.1%
  • Sepsis: 3%
27 (79.4%) 7 (20.6%)
Chereau, 2011 ≥70 years 29

Two-year: 35%

Five-year: 23%		 Five-year: 55% 1 (3.4%)
  • Overall: 3 (10%)
  • Infection: 2 (7%)
  • Febrile morbidity: 1 (3%)
  • Pleural effusion: 1 (3%)
29 (100%) Study exclusion
Langstraat, 2011 ≥65 years 280 NA NA 12 (4.3%) Overall: 32 (11.4%) 280 (100%) Study exclusion
Fanfani, 2012 ≥65 years 164

65 to 74 years: 12 months

≥75 years: 21 months		 NA 0

Overall:

65 to 74 years: 11 (11.2%)

≥75 years: 8 (25%)		 75 (45.7%) 89 (54.3%)
PFS: progression-free survival; NA: not applicable, recorded, or extractable from the publication for this specific subset of patients; OS: overall survival; 1o: primary; ICU: intensive care unit; VTE: venous thromboembolism; GI: gastrointestinal; NACT: neoadjuvant chemotherapy.
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