دسترسی یکساله به بیش از ۵۰۰ ژورنال روز جهان موجود در سامانه
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Effect of Vitamin D3 Supplementation on Severe Asthma Exacerbations in Children With Asthma and Low Vitamin D LevelsThe VDKA Randomized Clinical Trial
Erick Forno, MD, MPH; Leonard B. Bacharier, MD; Wanda Phipatanakul, MD, MS; et al.
doi : 10.1001/jama.2020.12384
JAMA. 2020;324(8):752-760.
This randomized trial compares the effects of vitamin D3 vs placebo on time to severe exacerbation in children with asthma and low vitamin D levels.
Effect of Genotype-Guided Oral P2Y12 Inhibitor Selection vs Conventional Clopidogrel Therapy on Ischemic Outcomes After Percutaneous Coronary InterventionThe TAILOR-PCI Randomized Clinical Trial
Naveen L. Pereira, MD; Michael E. Farkouh, MD, MSc; Derek So, MD; et al.
doi : 10.1001/jama.2020.12443
JAMA. 2020;324(8):761-771.
This open-label randomized trial compares the effect of a genotype-guided oral P2Y12 inhibitor selection strategy vs conventional clopidogrel prescribing on 12-month ischemic outcomes after percutaneous coronary intervention (PCI) in CYP2C19*2/CYP2C19*3 loss-of-function allele carriers with acute coronary syndromes and stable cardiovascular disease.
Discriminative Accuracy of Plasma Phospho-tau217 for Alzheimer Disease vs Other Neurodegenerative Disorders
Sebastian Palmqvist, MD, PhD; Shorena Janelidze, PhD; Yakeel T. Quiroz, PhD; et al.
doi : 10.1001/jama.2020.12134
JAMA. 2020;324(8):772-781.
This cross-sectional study compares the accuracy of plasma tau phosphorylated at threonine 217 (P-tau217) levels vs other plasma-, MRI-, CSF-, and PET-based markers for distinguishing Alzheimer from other neurodegenerative diseases in 3 cohorts in Arizona, Sweden, and Columbia with or at risk for dementia.
Thrombosis in Hospitalized Patients With COVID-19 in a New York City Health System
Seda Bilaloglu, MS; Yin Aphinyanaphongs, MD, PhD; Simon Jones, PhD, MSc; et al.
doi : 10.1001/jama.2020.13372
JAMA. 2020;324(8):799-801.
This study examines the incidence of and risk factors for venous and arterial thrombosis in patients hospitalized with COVID-19 in 4 New York City hospitals.
Ketoacidosis in Children and Adolescents With Newly Diagnosed Type 1 Diabetes During the COVID-19 Pandemic in Germany
Clemens Kamrath, MD; Kirsten M?nkem?ller, MD; Torben Biester, MD; et al.
doi : 10.1001/jama.2020.13445
JAMA. 2020;324(8):801-804.
This study uses diabetes registry data to compare the frequency of diabetic ketoacidosis (DKA) in children and adolescents at time of type 1 diabetes diagnosis in Germany during the first 2 months of the coronavirus disease 2019 (COVID-19) pandemic vs the same time period in 2018 and 2019.
Therapies Offered at Residential Addiction Treatment Programs in the United States
Tamara Beetham, MPH; Brendan Saloner, PhD; Marema Gaye, BS; et al.
doi : 10.1001/jama.2020.8969
JAMA. 2020;324(8):804-806.
This study uses simulated patient calls to a random sample of US residential addiction treatment facilities to investigate the availability of opioid agonist treatment (buprenorphine-naloxone) and nonpharmacologic therapies (eg, CBT) for opioid use disorder, and differences by for-profit vs nonprofit center status.
Precision Nutrition—the Answer to “What to Eat to Stay Healthy”
Griffin P. Rodgers, MD; Francis S. Collins, MD, PhD
doi : 10.1001/jama.2020.13601
JAMA. 2020;324(8):735-736.
In this Viewpoint directors of the NIH and NIDDK summarize the agency’s 2020-2030 Strategic Plan for NIH Nutrition Research, a roadmap to establish a science of nutrition as a means to prevent and treat illness and to develop actionable, evidence-based dietary recommendations across cultures and settings.
Black Kidney Function MattersUse or Misuse of Race?
Neil R. Powe, MD, MPH, MBA
doi : 10.1001/jama.2020.13378
JAMA. 2020;324(8):737-738.
This Viewpoint discusses the practice of using patient race as a variable in algorithms to determine kidney function and suggests that estimating tools be developed that are equally precise but exclude race as a factor.
Recovery From Severe COVID-19Leveraging the Lessons of Survival From Sepsis
Hallie C. Prescott, MD, MSc; Timothy D. Girard, MD, MSCI
doi : 10.1001/jama.2020.14103
JAMA. 2020;324(8):739-740
This Viewpoint discusses the possibility that survivors of severe COVID-19 will experience persistent symptoms similar to those of post-sepsis syndrome and reviews best practices for promoting recovery from intensive care illness, including referral to physical and occupational therapy, medication optimization, and structured exercise.
Attacks on Public Health Officials During COVID-19
Michelle M. Mello, JD, PhD; Jeremy A. Greene, MD, PhD; Joshua M. Sharfstein, MD
doi : 10.1001/jama.2020.14423
JAMA. 2020;324(8):741-742.
This Viewpoint discusses ongoing harassment and threats against US public health officials who propose or take steps to protect communities from coronavirus disease 2019 (COVID-19) and it proposes possible responses, including a call to elected leaders to implement protection of the officials from illegal harassment, assault, and violence.
COVID-19 in CanadaExperience and Response
Allan S. Detsky, MD, PhD; Isaac I. Bogoch, MD
doi : 10.1001/jama.2020.14033
JAMA. 2020;324(8):743-744
This Viewpoint summarizes federal, provincial, and regional responses to the COVID-19 pandemic in Canada and explores reasons for differences in pandemic outcomes in Canada and the US.
Growing Pains
Maïté Van Hentenryck, BS, MS
doi : 10.1001/jama.2020.13442
JAMA. 2020;324(8):745-746.
In this narrative medicine essay, a medical student describes her experience growing up with a leg prosthesis and requiring orthopedic procedures to maintain her limb growth and describes reactions to her disability from uncomprehending peers and mentors in her medical training.
CYP2C19 Genotyping to Guide Antiplatelet Therapy After Percutaneous Coronary InterventionsOne Size Rarely Fits All
David J. Moliterno, MD; Susan S. Smyth, MD, PhD; Ahmed Abdel-Latif, MD, PhD
doi : 10.1001/jama.2020.13094
JAMA. 2020;324(8):747-749.
Serosurveillance and the COVID-19 Epidemic in the USUndetected, Uncertain, and Out of Control
Tyler S. Brown, MD; Rochelle P. Walensky, MD, MPH
doi : 10.1001/jama.2020.14017
JAMA. 2020;324(8):749-751.
Pathophysiology, Transmission, Diagnosis, and Treatment of Coronavirus Disease 2019 (COVID-19)A Review
W. Joost Wiersinga, MD, PhD; Andrew Rhodes, MD, PhD; Allen C. Cheng, MD, PhD; et al.
doi : 10.1001/jama.2020.12839
JAMA. 2020;324(8):782-793.
This narrative review discusses what is currently known about the pathophysiology, epidemiology, diagnosis, management, prognosis, and prevention of coronavirus disease 2019 (COVID-19).
Current Perspective on Age-Related Macular Degeneration
Usha Chakravarthy, MD, PhD; Tunde Peto, MD, PhD
doi : 10.1001/jama.2020.5576
JAMA. 2020;324(8):794-795.
This JAMA Insights Clinical Update reviews the epidemiology, clinical manifestations, classification, diagnosis, prevention, and approved and investigational treatment of age-related macular degeneration in older adults.
Postexercise Ankle-Brachial Index Testing
Anurag Mehta, MD; Laurence S. Sperling, MD; Bryan J. Wells, MD
doi : 10.1001/jama.2020.10164
JAMA. 2020;324(8):796-797.
A 61-year-old woman with a history of hypertension presented for evaluation of exertional left calf discomfort. Her lower extremity systolic blood pressure and ankle-brachial index (ABI) measures declined after treadmill testing. What would you do next?
From Auto Mechanic to Emergency Medicine Resident: Inspiring Young Blacks to Become Physicians
Rita Rubin, MA
doi : 10.1001/jama.2020.14306
JAMA. 2020;324(8):727-729.
This Medical News article discusses the circuitous path Carl Allamby, MD, traveled from auto repair shop owner to emergency medicine resident.
Experts Discuss COVID-19—Remdesivir, Vaccines, and More
doi : 10.1001/jama.2020.15067
JAMA. 2020;324(8):730-731.
This JAMA Live Highlights feature provides comments about the coronavirus 2019 pandemic from experts in clinical medicine, public health, and health policy expressed during livestream interviews with JAMA Network Editor in Chief Howard Bauchner, MD.
Football-Related Head Injuries Decline Among Children and Teens
Bridget M. Kuehn, MSJ
doi : 10.1001/jama.2020.14163
JAMA. 2020;324(8):734.
Lung Diseases Affecting US Workers Cost Billions Annually
Bridget M. Kuehn, MSJ
doi : 10.1001/jama.2020.14764
JAMA. 2020;324(8):734.
Elagolix Reduces Fibroid-Related Heavy Menstrual Bleeding Long-term
Anita Slomski, MA
doi : 10.1001/jama.2020.13960
JAMA. 2020;324(8):733.
Aspirin Fails to Prevent Depression in Older Adults
Anita Slomski, MA
doi : 10.1001/jama.2020.14802
JAMA. 2020;324(8):733.
Shorter Resident Shifts May Not Improve Patient Safety
Anita Slomski, MA
doi : 10.1001/jama.2020.14803
JAMA. 2020;324(8):733.
Mailings, Phone Calls Increase Post-MI Cardiac Rehabilitation
Anita Slomski, MA
doi : 10.1001/jama.2020.14805
JAMA. 2020;324(8):733.
Aspirin Protects Against Colorectal Cancer in Lynch Syndrome
Anita Slomski, MA
doi : 10.1001/jama.2020.14804
JAMA. 2020;324(8):733
Household Composition May Explain COVID-19 Racial/Ethnic Disparities
Rita Rubin, MA
doi : 10.1001/jama.2020.14375
JAMA. 2020;324(8):732.
Difficult to Determine Herd Immunity Threshold for COVID-19
Rita Rubin, MA
doi : 10.1001/jama.2020.14778
JAMA. 2020;324(8):732
Streetlights May Keep Teens Up at Night, Affecting Mental Health
Rita Rubin, MA
doi : 10.1001/jama.2020.14785
JAMA. 2020;324(8):732.
A Song Sung Sweet to Greet the Dead
Glenn Colquhoun, MD
doi : 10.1001/jama.2020.6795
JAMA. 2020;324(8):810.
Renaudot and the First French Newspaper and Medical Journal
doi : 10.1001/jama.2019.13587
JAMA. 2020;324(8):811.
What Is LASIK Eye Surgery?
Malcolm M. Kates, BS, BA; Sonal Tuli, MD
doi : 10.1001/jama.2020.1286
JAMA. 2020;324(8):815.
This JAMA Patient Page describes LASIK, a type of laser surgery that corrects blurry vision usually treated with eyeglasses, and summarizes who can benefit and the procedure’s risks.
What Is COVID-19?
W. Joost Wiersinga, MD, PhD, MBA; Hallie C. Prescott, MD, MSc
doi : 10.1001/jama.2020.12984
JAMA. 2020;324(8):816.
This JAMA Patient Page provides an overview of COVID-19 transmission, symptoms, diagnosis, disease course, and treatment.
Reducing Intraoperative Hypotension Using a Machine Learning–Derived Early Warning System
Christian de Tymowski, MD; Dan Longrois, PhD; Philippe Montravers, PhD
doi : 10.1001/jama.2020.9049
JAMA. 2020;324(8):806-807.
Reducing Intraoperative Hypotension Using a Machine Learning–Derived Early Warning System—Reply
Bart F. Geerts, MD, PhD, MSc, MBA; Alexander P. Vlaar, MD, PhD, MBA; Denise P. Veelo, MD, PhD
doi : 10.1001/jama.2020.9064
JAMA. 2020;324(8):807-808
Drug Shortages and Group Purchasing Organizations
Khatereh Calleja, JD
doi : 10.1001/jama.2020.9055
JAMA. 2020;324(8):808-809.
Drug Shortages and Group Purchasing Organizations—Reply
Julie M. Donohue, PhD; Inmaculada Hernandez, PharmD, PhD; Tina Batra Hershey, JD, MPH
doi : 10.1001/jama.2020.9058
JAMA. 2020;324(8):809.
