دسترسی یکساله به بیش از ۵۰۰ ژورنال روز جهان موجود در سامانه
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No More Surprises — New Legislation on Out-of-Network Billing
Karan R. Chhabra, M.D., Erin Fuse Brown, J.D., M.P.H., and Andrew M. Ryan, Ph.D.
doi : 10.1056/NEJMp2035905
N Engl J Med 2021; 384:1381-1383
Remote Patient Monitoring — Overdue or Overused?
Keizra Mecklai, B.S., Nicholas Smith, B.S., Ariel D. Stern, Ph.D., and Daniel B. Kramer, M.D., M.P.H.
doi : 10.1056/NEJMp2033275
N Engl J Med 2021; 384:1384-1386
Race, Policing, and History — Remembering the Freedom House Ambulance Service
Matthew L. Edwards, M.D.
doi : 10.1056/NEJMp2035467
N Engl J Med 2021; 384:1386-1389
Hypothermic Machine Perfusion in Liver Transplantation — A Randomized Trial
Rianne van Rijn, M.D., Ph.D., Ivo J. Schurink, B.Sc., Yvonne de Vries, M.D., Ph.D., Aad P. van den Berg, M.D., Ph.D., Miriam Cortes Cerisuelo, M.D., Ph.D., Sarwa Darwish Murad, M.D., Ph.D., Joris I. Erdmann, M.D, Ph.D., Nicholas Gilbo, M.D., Ph.D., Robbert J. de Haas, M.D., Ph.D., Nigel Heaton, M.D., Ph.D., Bart van Hoek, M.D., Ph.D., Volkert A.L. Huurman, M.D., Ph.D., Ina Jochmans, M.D., Ph.D., Otto B. van Leeuwen, Ph.D., Vincent E. de Meijer, M.D., Ph.D., Diethard Monbaliu, M.D., Ph.D., Wojciech G. Polak, M.D., Ph.D., Jules J.G. Slangen, M.D., Roberto I. Troisi, M.D., Ph.D., Aude Vanlander, M.D., Ph.D., Jeroen de Jonge, M.D., Ph.D., and Robert J. Porte, M.D., Ph.D. for the DHOPE-DCD Trial Investigators*
doi : 10.1056/NEJMoa2031532
N Engl J Med 2021; 384:1391-1401
Transplantation of livers obtained from donors after circulatory death is associated with an increased risk of nonanastomotic biliary strictures. Hypothermic oxygenated machine perfusion of livers may reduce the incidence of biliary complications, but data from prospective, controlled studies are limited.
Trial of Psilocybin versus Escitalopram for Depression
Robin Carhart-Harris, Ph.D., Bruna Giribaldi, B.Sc., Rosalind Watts, D.Clin.Psy., Michelle Baker-Jones, B.A., Ashleigh Murphy-Beiner, M.Sc., Roberta Murphy, M.D., Jonny Martell, M.D., Allan Blemings, M.Sc., David Erritzoe, M.D., and David J. Nutt, M.D.
doi : 10.1056/NEJMoa2032994
N Engl J Med 2021; 384:1402-1411
Psilocybin may have antidepressant properties, but direct comparisons between psilocybin and established treatments for depression are lacking.
BNT162b2 mRNA Covid-19 Vaccine in a Nationwide Mass Vaccination Setting
Noa Dagan, M.D., Noam Barda, M.D., Eldad Kepten, Ph.D., Oren Miron, M.A., Shay Perchik, M.A., Mark A. Katz, M.D., Miguel A. Hern?n, M.D., Marc Lipsitch, D.Phil., Ben Reis, Ph.D., and Ran D. Balicer, M.D.
doi : 10.1056/NEJMoa2101765
N Engl J Med 2021; 384:1412-1423
As mass vaccination campaigns against coronavirus disease 2019 (Covid-19) commence worldwide, vaccine effectiveness needs to be assessed for a range of outcomes across diverse populations in a noncontrolled setting. In this study, data from Israel’s largest health care organization were used to evaluate the effectiveness of the BNT162b2 mRNA vaccine.
Dexmedetomidine or Propofol for Sedation in Mechanically Ventilated Adults with Sepsis
Christopher G. Hughes, M.D., M.S.C.R., Patrick T. Mailloux, D.O., John W. Devlin, Pharm.D., Joshua T. Swan, Pharm.D., M.P.H., Robert D. Sanders, M.D., Antonio Anzueto, M.D., James C. Jackson, Psy.D., Aimee S. Hoskins, B.S.N., R.N., Brenda T. Pun, D.N.P., R.N., Onur M. Orun, M.S., Rameela Raman, Ph.D., Joanna L. Stollings, Pharm.D., Amy L. Kiehl, M.A., Matthew S. Duprey, Pharm.D., Ph.D., Lan N. Bui, Pharm.D., M.P.H., Hollis R. O’Neal, Jr., M.D., Allison Snyder, M.S.N., A.P.R.N., Michael A. Gropper, M.D., Ph.D., Kalpalatha K. Guntupalli, M.D., Gregg J. Stashenko, M.D., Mayur B. Patel, M.D., M.P.H., Nathan E. Brummel, M.D., M.S.C.I., Timothy D. Girard, M.D., M.S.C.I., Robert S. Dittus, M.D., M.P.H., Gordon R. Bernard, M.D., E. Wesley Ely, M.D., M.P.H., and Pratik P. Pandharipande, M.D., M.S.C.I. for the MENDS2 Study Investigators*
doi : 10.1056/NEJMoa2024922
N Engl J Med 2021; 384:1424-1436
Guidelines currently recommend targeting light sedation with dexmedetomidine or propofol for adults receiving mechanical ventilation. Differences exist between these sedatives in arousability, immunity, and inflammation. Whether they affect outcomes differentially in mechanically ventilated adults with sepsis undergoing light sedation is unknown.
Insights into Glomerular Filtration and Albuminuria
Thomas Benzing, M.D., and David Salant, M.D.
doi : 10.1056/NEJMra1808786
N Engl J Med 2021; 384:1437-1446
Palmoplantar Papules
Benjamin Klein, M.D., and Regina Treudler, M.D.
doi : 10.1056/NEJMicm2032907
N Engl J Med 2021; 384:1447
Closed Gastroschisis
Tyler D. Robinson, M.D., M.P.H., and Christine Whyte, M.D.
doi : 10.1056/NEJMicm2029281
N Engl J Med 2021; 384:e56
Case 11-2021: A 39-Year-Old Woman with Fever, Flank Pain, and Inguinal Lymphadenopathy
Richelle C. Charles, M.D., Madeleine Sertic, M.B., Ch.B., Anne M. Neilan, M.D., M.P.H., and Aliyah R. Sohani, M.D.
doi : 10.1056/NEJMcpc2100273
N Engl J Med 2021; 384:1448-1456
Warming Up to Cold Perfusion
Winfred W. Williams, M.D., and James F. Markmann, M.D., Ph.D.
doi : 10.1056/NEJMe2102056
N Engl J Med 2021; 384:1458-1459
Back to the Future — The Therapeutic Potential of Psychedelic Drugs
Jeffrey A. Lieberman, M.D.
doi : 10.1056/NEJMe2102835
N Engl J Med 2021; 384:1460-1461
Audio Interview: Vaccine Successes and Vaccine Adverse Events
Eric J. Rubin, M.D., Ph.D., Lindsey R. Baden, M.D., and Stephen Morrissey, Ph.D.
doi : 10.1056/NEJMe2106379
N Engl J Med 2021; 384:e70
No Cure without Care — Soothing Science Skepticism
Lisa Rosenbaum, M.D.
doi : 10.1056/NEJMms2101989
N Engl J Med 2021; 384:1462-1465
Neutralizing Activity of BNT162b2-Elicited Serum
doi : 10.1056/NEJMc2102017
N Engl J Med 2021; 384:1466-1468
Serum Neutralizing Activity Elicited by mRNA-1273 Vaccine
doi : 10.1056/NEJMc2102179
N Engl J Med 2021; 384:1468-1470
Cardiovascular Outcomes with Sotagliflozin
doi : 10.1056/NEJMc2102961
N Engl J Med 2021; 384:1470-1473
Tocilizumab in Patients Hospitalized with Covid-19 Pneumonia
doi : 10.1056/NEJMc2100217
N Engl J Med 2021; 384:1473-1474
Phase 3 Trial of Interleukin-1 Trap Rilonacept in Recurrent Pericarditis
doi : 10.1056/NEJMc2101978
N Engl J Med 2021; 384:1474-1476
