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Searching the puerperal trigger of bipolar disorder
Verinder Sharma,Dwight Mazmanian
doi : 10.1111/bdi.13060
Volume 23, Issue 5 p. 439-441
Inflammation and disease modification in bipolar disorders: Priority avenues for future research
Hartej Gill,Joshua Daniel Rosenblat,Rodrigo B. Mansur,Roger S. McIntyre
doi : 10.1111/bdi.13104
Volume 23, Issue 5 p. 442-444
Effect of lithium on circadian rhythm in bipolar disorder: A systematic review and meta-analysis
Ni Xu,Kiyomi Shinohara,Kate E. A. Saunders,John R. Geddes,Andrea Cipriani
doi : 10.1111/bdi.13070
Volume 23, Issue 5 p. 445-453
Circadian rhythm disruption is commonly reported in patients with bipolar disorder. Lithium has been suggested to have effects on the circadian clock, the biological basis of the circadian rhythm. The objective of the current review was to review systematically the existing studies on the effect of lithium on circadian rhythm in patients with bipolar disorder.
Incidence of Parkinson’s disease, dementia, cerebrovascular disease and stroke in bipolar disorder compared to other psychiatric disorders: An electronic health records network study of 66 million people
Paul J. Harrison,Sierra Luciano
doi : 10.1111/bdi.13022
Volume 23, Issue 5 p. 454-462
Bipolar disorder has been associated with an increased risk for neurodegenerative diseases, but uncertainties remain. The risk relative to other psychiatric disorders is not established.
Prospectively ascertained mania and hypomania among young adults with child- and adolescent-onset bipolar disorder
Danella M. Hafeman,Tina R. Goldstein,Michael Strober,John Merranko,Mary Kay Gill,Fangzi Liao,Rasim S. Diler,Neal D. Ryan,Benjamin I. Goldstein,David A. Axelson,Martin B. Keller,Jeffrey I. Hunt,Heather Hower,Lauren M. Weinstock,Shirley Yen,Boris Birmaher
doi : 10.1111/bdi.13034
Volume 23, Issue 5 p. 463-473
While adults with bipolar disorder (BD) often report symptoms starting in childhood, continuity of mania and/or hypomania (mania/hypomania) from childhood to adulthood has been questioned. Using longitudinal data from the Course and Outcome of Bipolar Youth (COBY) study, we assessed threshold mania/hypomania in young adults who manifested BD as youth. Methods: COBY is a naturalistic, longitudinal study of 446 youth with BD (84% recruited from outpatient clinics), 7–17 years old at intake, and over 11 years of follow-up. Focusing on youth with BD-I/II (n = 297), we examined adult mania/hypomania risk (>18 years old; mean 7.9 years of follow-up) according to child (<13 years old) versus adolescent (13–17 years old) onset. We next used penalized regression to test demographic and clinical predictors of young adult mania/hypomania. Results: Most participants (64%) had child-onset mania/hypomania, 57% of whom also experienced mania/hypomania in adolescence. Among those who experienced an episode in adolescence, over 40% also had mania/hypomania during adulthood; the risk did not differ according to child versus adolescent onset. In contrast, 7% with mania/hypomania in childhood, but not adolescence, experienced mania/hypomania in adulthood. Family history (of mania and suicide attempts) predicted mania/hypomania in young adulthood (p-values <0.05); age of onset was not a significant predictor. Among participants with no mania/hypomania during adulthood, 53% (105/198) still experienced subthreshold manic episodes. Discussion: We find substantial continuity across developmental stage indicating that, in this carefully characterized sample, children who experience mania/hypomania—particularly those who also experience mania/hypomania in adolescence—are likely to experience mania/hypomania in young adulthood.
Alterations in resting-state global brain connectivity in bipolar I disorder patients with prior suicide attempt
Xiaofang Cheng,Jianshan Chen,Xiaofei Zhang,Yihe Zhang,Qiuxia Wu,Qing Ma,Jiaqi Sun,Wenjin Zou,Taifeng Lin,Liangda Zhong,Wenhao Deng,Xiaoyi Sun,Liqian Cui,Xiongchao Cheng,Yingmei Chen,Yinglian Cai,Chaodun Zheng,Daomeng Cheng,Chanjuan Yang,Biyu Ye,Xiangyang Zhang,Xinhua Wei,Liping Cao
doi : 10.1111/bdi.13012
Volume 23, Issue 5 p. 474-486
Bipolar I disorder (BD-I) is associated with a high risk of suicide attempt; however, the neural circuit dysfunction that confers suicidal vulnerability in individuals with this disorder remains largely unknown. Resting-state functional magnetic resonance imaging (rs-fMRI) allows non-invasive mapping of brain functional connectivity. The current study used an unbiased voxel-based graph theory analysis of rs-fMRI to investigate the intrinsic brain networks of BD-I patients with and without suicide attempt.
Effect of Action-Based Cognitive Remediation on cognitive impairment in patients with remitted bipolar disorder: A randomized controlled trial
Caroline V. Ott,Maj Vinberg,Lars V. Kessing,Christopher R. Bowie,Julie L. Forman,Kamilla W. Miskowiak
doi : 10.1111/bdi.13021
Volume 23, Issue 5 p. 487-499
Cognitive impairment affects many patients with bipolar disorder (BD), and treatments with replicated pro-cognitive effects are lacking. This study aimed to assess the effect of Action-Based Cognitive Remediation (ABCR) vs control treatment on cognitive impairment in patients with BD.
Variation in rostral anterior cingulate functional connectivity with amygdala and caudate during first manic episode distinguish bipolar young adults who do not remit following treatment
Elizabeth T. C. Lippard,Wade Weber,Jeffrey Welge,Caleb M. Adler,David E. Fleck,Jorge Almeida,Melissa P. DelBello,Stephen M. Strakowski
doi : 10.1111/bdi.13025
Volume 23, Issue 5 p. 500-508
Altered activity in the ventrolateral prefrontal and anterior cingulate cortices, as well as subcortical and amygdala projection sites, was previously reported during a first manic episode in youth with bipolar disorder and observed to be associated with treatment response. To extend these findings, we investigated functional connectivity among these regions in first-episode manic participants who remitted after 8 weeks of treatment compared to those who did not.
Evidence-based versus clinical expertise guidelines for Bipolar Disorders
Beny Lafer,Andrew A. Nierenberg
doi : 10.1111/bdi.13071
Volume 23, Issue 5 p. 509-510
Beyond evidence and toward long-term and individualized management of bipolar disorder in real-world practice
Aroldo A. Dargél
doi : 10.1111/bdi.13072
Volume 23, Issue 5 p. 511-512
Commentary on “The 2020 Royal Australian and New Zealand College of psychiatrists clinical practice guidelines for mood disorders: Bipolar disorder summary”
Brisa Solé,Anabel Mart?nez-Aran,Eduard Vieta,Carla Torrent
doi : 10.1111/bdi.13073
Volume 23, Issue 5 p. 513-514
Babies, bathwater, and bipolar disorder: Is it time to call curtains on staging?
Hailey Tremain,Kathryn Fletcher,Greg Murray
doi : 10.1111/bdi.13077
Volume 23, Issue 5 p. 515-516
Questions in Psychiatry (QuiP): Is staging bipolar disorder possible? If so, where to begin?
Gin S. Malhi,Erica Bell
doi : 10.1111/bdi.13103
Volume 23, Issue 5 p. 517-520
Aripiprazole in the treatment of bipolar disorder due to traumatic brain injury: A case description
Sergio Fern?ndez Leonor,Xabier Pérez de Mendiola Etxezarraga
doi : 10.1111/bdi.13038
Volume 23, Issue 5 p. 521-523
ECT for a pregnant patient with bipolar disorder in the COVID-19 Era: A clinical conundrum
Jessica M. Gannon,Priya Gopalan,LalithKumar K. Solai,Grace Lim,Jaclyn M. Phillips,Stacy Beck,Eydie Moses-Kolko,Donald Miller,K.N. Roy Chengappa
doi : 10.1111/bdi.13061
Volume 23, Issue 5 p. 524-527
Expanding the target audience for management guidelines: Co-development of the patient and family guide to the CANMAT and ISBD bipolar disorder guidelines
Ayal Schaffer,Sagar V. Parikh,Simina Toma,Natasha Thexton,Andrew Kcomt,Mike Griffiths,Lakshmi N. Yatham
doi : 10.1111/bdi.13094
Volume 23, Issue 5 p. 528-530
