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Recommendations for planning and delivery of radical radiotherapy for localized urothelial carcinoma of the bladder
JonathanKhalifaaStéphaneSupiotbGéraldinePignotcChristopheHennequindPierreBlanchardeDavidPasquierfNicolasMagnégRenaudde CrevoisierhPierreGraff-CailleaudaOlivierRiouiMorganeCabailléjDavidAzriaiIgorLatorzeffkGillesCréhangelOlivierChapetmMorganRouprêtnSarahBelhommeoArnaudMejeanpStéphaneCulineqPaulSargosj
doi : 10.1016/j.radonc.2021.06.011
Volume 161, August 2021, Pages 95-114
Curative radio-chemotherapy is recognized as a standard treatment option for muscle-invasive bladder cancer (MIBC). Nevertheless, the technical aspects for MIBC radiotherapy are heterogeneous with a lack of practical recommendations.
A systematic review on the usage of averaged LET in radiation biology for particle therapy
FredrikKalholmab1LeszekGrzankac2ErikTraneusd3NielsBasslerabefg4
doi : 10.1016/j.radonc.2021.04.007
Volume 161, August 2021, Pages 211-221
Linear Energy Transfer (LET) is widely used to express the radiation quality of ion beams, when characterizing the biological effectiveness. However, averaged LET may be defined in multiple ways, and the chosen definition may impact the resulting reported value. We review averaged LET definitions found in the literature, and quantify which impact using these various definitions have for different reference setups. We recorded the averaged LET definitions used in 354 publications quantifying the relative biological effectiveness (RBE) of hadronic beams, and investigated how these various definitions impact the reported averaged LET using a Monte Carlo particle transport code. We find that the kind of averaged LET being applied is, generally, poorly defined. Some definitions of averaged LET may influence the reported averaged LET values up to an order of magnitude. For publications involving protons, most applied dose averaged LET when reporting RBE. The absence of what target medium is used and what secondary particles are included further contributes to an ill-defined averaged LET. We also found evidence of inconsistent usage of averaged LET definitions when deriving LET-based RBE models. To conclude, due to commonly ill-defined averaged LET and to the inherent problems of LET-based RBE models, averaged LET may only be used as a coarse indicator of radiation quality. We propose a more rigorous way of reporting LET values, and suggest that ideally the entire particle fluence spectra should be recorded and provided for future RBE studies, from which any type of averaged LET (or other quantities) may be inferred.
The first-in-human implementation of adaptive 4D cone beam CT for lung cancer radiotherapy: 4DCBCT in less time with less dose
Ricky T.O'BrienaOwenDillonaBenjaminLauaArmiaGeorgebSandieSmithbAndrewWallisbJan-JakobSonkedPaul J.KeallaShalini K.Vinodbc
doi : 10.1016/j.radonc.2021.05.021
Volume 161, August 2021, Pages 29-34
We present the first implementation of Adaptive 4D cone beam CT (4DCBCT) that adapts the image hardware (gantry rotation speed and kV projections) in response to the patient’s real-time respiratory signal. Adaptive 4DCBCT was applied on lung cancer patients to reduce the scan time and imaging dose in the ADaptive CT Acquisition for Personalised Thoracic imaging (ADAPT) trial.
Early health economic analysis of 1.5 T MRI-guided radiotherapy for localized prostate cancer: Decision analytic modelling
CharismaHehakayaabJochem R.N.van der Voort van ZypaBen G.L.VannestecJanneke P.C.GruttersdDiederick E.GrobbeebefHelena M.VerkooijenafGeert W.J.Frederixe
doi : 10.1016/j.radonc.2021.05.022
Volume 161, August 2021, Pages 74-82
1.5 Tesla magnetic resonance imaging radiotherapy linear accelerator (MR-Linac) is gaining interest for treatment of localized prostate cancer. Clinical evidence is lacking and it therefore remains uncertain whether MR-Linac is cost-effective. An early health economic analysis was performed to calculate the necessary relative reduction in complications and the maximum price of MR-Linac (5 fractions) to be cost-effective compared to 5, 20 and 39 fractionation schedules of external beam radiotherapy (EBRT) and low-dose-rate (LDR) brachytherapy.
Outcomes of extra-cranial stereotactic body radiotherapy for metastatic breast cancer: Treatment indication matters
HendrickTanaPatrickCheungaAlexander V.LouieaStenMyrehaugaMarkNiglasbcEshetu G.AtenafudWilliamChuaHans T.ChungaIanPoonaArjunSahgalaHanySolimana
doi : 10.1016/j.radonc.2021.06.012
Volume 161, August 2021, Pages 159-165
To summarize the clinical outcomes of stereotactic body radiotherapy (SBRT) for metastatic breast cancer (mBC) from a large institution.
Observational cohort study in older women with early breast cancer: Use of radiation therapy and impact on health-related quality of life and mortality
Nicol? Matteo LucaBattistiaMatthew Q.HattonbMalcolm W.R.ReedcEstherHerbertdJenna L.MorganeMichaelBradburndRichardSimcockfStephen J.WaltersdKaren A.CollinsgSue E.WardhGeoffrey R.HolmeshMariaBurtongKate J.LiffordiAdrianEdwardsiThompson G.RobinsonjCharleneMartineTimChaterdKirsty J.PembertondAlanBrennanhKwokLeung CheungkAnnalizaToddeRiccardo A.AudisiolJulietWrightcTracyGreenmDeirdreRevellmJacquiGathmKieranHorgannChrisHolcombeoMatthew C.WinterpJayNaikqRishiParmeshwarrMargot A.GosneysAlastair M.ThompsontLyndaWylde1AlistairRinga1on behalf of theBridging the Age Gap TMG
doi : 10.1016/j.radonc.2021.06.021
Volume 161, August 2021, Pages 166-176
Radiotherapy reduces in-breast recurrence risk in early breast cancer (EBC) in older women. This benefit may be small and should be balanced against treatment effect and holistic patient assessment. This study described treatment patterns according to fitness and impact on health-related quality-of-life (HRQoL).
Superficial margins in skin sparing and nipple sparing mastectomies for DCIS: A margin of potential concern
TrineTrammaPeerChristiansenbBirgitte VrouOffersencKaren BerenthMadsendPhilipPoortmansefOritKaidar-Persongh
doi : 10.1016/j.radonc.2021.06.018
Volume 161, August 2021, Pages 177-182
Skin-sparing and nipple-sparing mastectomies with immediate reconstruction for breast cancer are increasing. The superficial fascia is considered a natural border and the superficial margin may not be evaluated. We emphasize the need for reporting of the superficial margin status in these procedures to obtain valid information on its association with local recurrence risks.
A novel nomogram for predicting locoregional recurrence risk in breast cancer patients treated with neoadjuvant chemotherapy and mastectomy
ZhouHuangab1MeiShic1Wei-HuWangb1Liang-FangShend1YuTangaQing-LinRongaLiZhueXiao-BoHuangfJianTiebJia-YiChengJunZhanghHong-FenWuiJingChengjMinLiukChang-YingMalShu-LianWangaYe-XiongLia
doi : 10.1016/j.radonc.2021.06.015
Volume 161, August 2021, Pages 191-197
This study aimed to establish a nomogram for predicting locoregional recurrence (LRR) in breast cancer patients treated with neoadjuvant chemotherapy (NAC) and mastectomy.
Hippocampal sparing in patients receiving radiosurgery for ?25 brain metastases
AmiKaviahJasonGurewitzbeCarolina GBenjaminiJoshua S.SilvermandeKennethBernsteindjMonicaMurebfCheongeunOhg1Erik P.SulmandeBernadineDonahuedehDouglasKondziolkacde
doi : 10.1016/j.radonc.2021.05.019
Volume 161, August 2021, Pages 65-71
To report our dosimetric analysis of the hippocampi (HC) and the incidence of perihippocampal tumor location in patients with ?25 brain metastases who received stereotactic radiosurgery (SRS) in single or multiple sessions.
Brain network hubs and cognitive performance of survivors of childhood infratentorial tumors
CharlotteSleursaSandraJacobsabSerena J.CounsellcDaanChristiaensceJ-DonaldTourniercStefanSunaertdeKarenVan BeekfAnneUyttebroeckabSabineDeprezeDafnisBatallecg1JurgenLemiereb1
doi : 10.1016/j.radonc.2021.05.028
Volume 161, August 2021, Pages 118-125
Childhood infratentorial tumor patients frequently suffer from long-term cognitive deficits. As each constituent of their treatment can lead to neurotoxicity, cascade effects can lead to profound reorganization of the underlying brain network, the so-called ‘connectome’. However, to date, few studies have assessed the relationship between brain network topology, the functional role of network hubs (i.e. highly connected regions), and neurocognitive outcomes in adult survivors of childhood infratentorial tumors.
Patterns of failure and implications for clinical target volume definition of locally advanced T4b rectal cancer identified with magnetic resonance imaging and treated using neoadjuvant chemoradiotherapy and surgery
Yang-ziZhangMaxiaoweiSongJian-haoGengXiang-gaoZhuShuaiLiYong-hengLiYongCaiWei-huWang
doi : 10.1016/j.radonc.2021.06.017
Volume 161, August 2021, Pages 132-139
Elective irradiation of the external iliac lymph nodes (EIN) has always been advocated for T4b rectal cancer with anterior organ invasion without convincing evidence. This study aimed to explore the patterns of treatment failure for locally advanced T4b rectal cancer treated using neoadjuvant chemoradiotherapy (NCRT) and surgery. This information may help to clarify whether the current definition of the clinical target volume (CTV) is still appropriate.
Image-based deep learning model for predicting pathological response in rectal cancer using post-chemoradiotherapy magnetic resonance imaging
Bum-SupJanga1Yu JinLimb1ChanghoonSongaSeung HyuckJeoncKeun-WookLeedSung-BumKangeYoon JinLeefJae-SungKima
doi : 10.1016/j.radonc.2021.06.019
Volume 161, August 2021, Pages 183-190
To develop an image-based deep learning model for predicting pathological response in rectal cancer using post-chemoradiotherapy magnetic resonance (MR) imaging.
Locoregional relapses in the ACCORD 12/0405-PRODIGE 02 study: Dosimetric study and risk factors?
NicolasMeillanabAlexandreOrthuoncPaulChauchatdDavidAtlanieOlivierBouchefBertrandChaulingCélineDavidhMélanieDeberneiCharlesDebrigodejWilliamKaokAudreyKellerlHortenseLahariemBrunoLamezecnClaireLemanskioNicolasMagnépMarc-AndréMahéqPascaleMererLaurenceMoureau-ZabottosDidierPeifferttYoannPointreauuLaurentQuérovSéverineRacadotwSophieRocaxPaulSargosyStéphanieServagizElianeTangacVéroniqueVendrelyaaabJérômeDoyenadFlorenceHuguetbaeaf
doi : 10.1016/j.radonc.2021.06.006
Volume 161, August 2021, Pages 198-204
The aim of this study is to correlate locoregional relapse with radiation therapy volumes in patients with rectal cancer treated with neoadjuvant chemoradiation in the ACCORD 12/0405-PRODIGE 02 trial.
Correlation analysis of neck node levels in 960 cases of Nasopharyngeal carcinoma (NPC)
ChaoyangJiangaBaolinGongbHuiGaoaTaoZhangaZhihuiLiaJuanWangbLingZhanga
doi : 10.1016/j.radonc.2021.05.020
Volume 161, August 2021, Pages 23-28
The delineation of intermediate risk nodal regions (CTVn2) and low-risk nodal regions (CTVn3) base on the correlation analysis between neck node levels of NPC has not been reported. We aim to analyze the correlations between different neck node levels in 960 cases of NPC, and to provide preliminary suggestions for clinical target volume (CTV) delineation of NPC base on the correlation analysis.
Independent external validation using the EORTC HNCG-ROG 1219 DAHANCA trial data of NTCP models for acute oral mucositis
M.SharabianiaE.ClementelaN.AndratschkebL.CollettecC.FortpiedaV.GrégoiredJ.OvergaardeJ.WillmannbC.Hurkmansf
doi : 10.1016/j.radonc.2021.04.006
Volume 161, August 2021, Pages 35-39
To externally validate previously published Normal Tissue Complication Probability (NTCP) models developed by separate teams for grade 3 oral mucositis (g3OM).
Optimal cumulative cisplatin dose during concurrent chemoradiotherapy among children and adolescents with locoregionally advanced nasopharyngeal carcinoma: A real-world data study
Ya-NanJina1Ji-JinYaob1Ya-FeiYoua1Hui-JiaoCaoa1Zi-ZiLicDan-LingDaidWang-JianZhangeTiaMarkseBeiZhangaLiang-PingXiaa
doi : 10.1016/j.radonc.2021.06.003
Volume 161, August 2021, Pages 83-91
To identify an optimal cumulative cisplatin dose along with concurrent chemoradiotherapy (CC-CCD) for children and adolescents with locoregionally advanced nasopharyngeal carcinoma (CALANPC) using real-world data.
Discovery of new salivary gland – A substantial histological analysis
N.B.PushpaaKumar SatishRavibcPrashantDurgapald
doi : 10.1016/j.radonc.2021.06.004
Volume 161, August 2021, Pages 92-94
Regardless of the COVID-19 pandemic in 2020, discovering a new salivary gland turned into all the rage among the medical fraternity. The significance of the disclosure has been correlated with its clinical relevance in radiotherapy of oropharyngeal carcinoma. However, there are views against this new revelation, owing to the lack of substantial evidence. We have endeavoured to illuminate Tubarial glands with potential shreds of evidence.
Precision association of lymphatic disease spread with radiation-associated toxicity in oropharyngeal squamous carcinomas
AndrewWentzela1TimothyLucianiaLisanne V.van DijkbNicoletteTakubBaherElgoharibeAbdallah S.R.MohamedbGuadalupeCanahuatedClifton D.FullerbDavid M.VockcG.Elisabeta MaraiaSpatial-Non-spatial Multi-Dimensional Analysis of Radiotherapy Treatment/Toxicity Team SMART3
doi : 10.1016/j.radonc.2021.06.016
Volume 161, August 2021, Pages 152-158
To determine whether patient similarity in terms of head and neck cancer spread through lymph nodes correlates significantly with radiation-associated toxicity.
Clinical features and dosimetric evaluation of carbon ion radiation-induced osteoradionecrosis of mandible in head and neck tumors
AtsushiMushaabHirofumiShimadaaNobuteruKuboaHidemasaKawamuraaNaokoOkanoaHiroSatoaTakuyaKaminumaaKoheiOkadaaMaiAnakuraaAkikoAdachiaKatsuyukiShiraiacJun-ichiSaitohadSatoshiYokoobKazuakiChikamatsueTatsuyaOhnoa
doi : 10.1016/j.radonc.2021.06.022
Volume 161, August 2021, Pages 205-210
Osteoradionecrosis (ORN) affects the patient’s quality of life by making eating and maintaining oral hygiene painful. This study aimed to analyze carbon ion radiotherapy (C-ion RT)-induced ORN of the mandible.
Radiation pneumonitis after palliative radiotherapy in cancer patients with interstitial lung disease
MasayukiOkumuraaHidehiroHojoaMasakiNakamuraaTakashiHiyamabNaokiNakamuracSadamotoZendaaAtsushiMotegiaYasuhiroHiranoaShun-IchiroKageyamaadRaturi VijayParshuramaTakeshiFujisawaaHirofumiKunobTetsuoAkimotoad
doi : 10.1016/j.radonc.2021.05.026
Volume 161, August 2021, Pages 47-54
The risk of radiation pneumonitis (RP) after palliative radiotherapy (RT) in cancer patients with interstitial lung disease (ILD) remains unclear. This study aimed to investigate the incidence, severity, and predictive factors of RP among patients with ILD who received palliative RT.
The prognostic value, sensitivity, and specificity of multiparametric magnetic resonance imaging before salvage radiotherapy for prostate cancer
William G.BreenaBradley J.StishaWilliam S.HarmsenbAdam T.FroemmingcLance A.MyndersedC. RichardChooaBrian J.DavisaThomas M.Pisanskya
doi : 10.1016/j.radonc.2021.05.015
Volume 161, August 2021, Pages 9-15
To determine the operational characteristics of pelvic magnetic resonance imaging (MRI) prior to salvage radiation therapy (SRT) for biochemically recurrent prostate cancer following radical prostatectomy.
Stereotactic pelvic radiotherapy with HDR boost for dose escalation in intermediate and high-risk prostate cancer (SPARE): Efficacy, toxicity and quality of life
Hima BinduMusunuruaPatrickCheungbcDannyVesprinibcStanley K.LiubcWilliamChubcHans T.ChungbcGerardMortonbcAndreaDeabreudMelanieDavidsonbcAnanthRavibcJoelleHelouceLingHocLiyingZhangdAndrewLoblawbcf
doi : 10.1016/j.radonc.2021.05.024
Volume 161, August 2021, Pages 40-46
The ASCO/CCO guidelines recommend brachytherapy (BT) boost for eligible intermediate- (IR) or high-risk (HR) prostate cancer (PCa) patients. We present efficacy, toxicity and quality-of-life (QoL) outcomes in patients treated on a prospective protocol of MRI dose-painted high-dose-rate BT boost (HDR-BT) followed by 5-fraction pelvic radiotherapy (RT) and 6–18 months of androgen deprivation therapy (ADT).
Second malignancy probabilities in prostate cancer patients treated with SBRT and other contemporary radiation techniques
Edward ChristopherDeea1VinayakMuralidharbMartin T.KingbNeil E.MartinbAnthony V.D'AmicobKent W.MouwbPeter F.OriobPaul L.NguyenbJonathan E.Leemanb
doi : 10.1016/j.radonc.2021.06.023
Volume 161, August 2021, Pages 241-250
Prostate radiotherapy has been associated with an increased risk of developing a second malignancy (SM). However, relative SM probabilities following treatment with contemporary radiation techniques such as stereotactic body radiotherapy (SBRT) or moderately hypofractionated intensity modulated radiotherapy (HF-IMRT) remain unknown.
CTV-to-PTV margin assessment for esophageal cancer radiotherapy based on an accumulated dose analysis
M.R.BoekhoffaI.L.DefizeabA.S.BorggreveabR.van HillegersbergbA.N.T.J.KotteaJ.J.W.LagendijkaA.L.H.M.W.van LieraJ.P.RuurdabN.TakahashiacS.Mooka1G.J.Meijera1
doi : 10.1016/j.radonc.2021.05.005
Volume 161, August 2021, Pages 16-22
This study aimed to assess the smallest clinical target volume (CTV) to planned target volume (PTV) margins for esophageal cancer radiotherapy using daily online registration to the bony anatomy that yield full dosimetric coverage over the course of treatment.
Stability of MRI contrast agents in high-energy radiation of a 1.5T MR-Linac
JihongWanga1TravisSalzillob1YongyingJiangcYuriMackeyevdCliftonDavid FullerbCarolineChungbSeungtaekChoibNeilHughesbYaoDingaJinzhongYangaSastryVedameSunilKrishnand
doi : 10.1016/j.radonc.2021.05.023
Volume 161, August 2021, Pages 55-64
Gadolinium-based contrast is often used when acquiring MR images for radiation therapy planning for better target delineation. In some situations, patients may still have residual MRI contrast agents in their tissue while being treated with high-energy radiation. This is especially true when MRI contrast agents are administered during adaptive treatment replanning for patients treated on MR-Linac systems.
Commissioning and clinical implementation of an Autoencoder based Classification-Regression model for VMAT patient-specific QA in a multi-institution scenario
RuijieYanga1XueyingYangb1LeWangcd1DingjieLieYuexinGuofYingLigYuminGuanhXiangyangWuiShoupingXujShumingZhangakMaria F.ChanlLishengGengbmJingSuidn
doi : 10.1016/j.radonc.2021.06.024
Volume 161, August 2021, Pages 230-240
To commission and implement an Autoencoder based Classification-Regression (ACLR) model for VMAT patient-specific quality assurance (PSQA) in a multi-institution scenario.
Evaluation of indirect damage and damage saturation effects in dose–response curves of hypofractionated radiotherapy of early-stage NSCLC and brain metastases
AraceliGago-AriasabcSaraNeiraaMiguelPombarbdAntonioG?mez-Caama?odeJuanPardo-Monteroab
doi : 10.1016/j.radonc.2021.05.012
Volume 161, August 2021, Pages 1-8
To investigate the possible contribution of indirect damage and damage saturation to tumour control obtained with SBRT/SRS treatments for early-stage NSCLC and brain metastases.
Effects of the DRD2/3 antagonist ONC201 and radiation in glioblastoma
LingHeaKruttikaBhataAngelikiIoannidisaLeZhangaNhan T.NguyenaJoshua E.AllenbPhioanh LeiaNghiemphucdTimothy F.CloughesycdLinda M.LiauceHarley I.KornblumcfFrankPajonkac
doi : 10.1016/j.radonc.2021.05.027
Volume 161, August 2021, Pages 140-147
Glioblastoma (GBM) is the deadliest of all brain cancers in adults. The current standard-of-care is surgery followed by radiotherapy and temozolomide, leading to a median survival time of only 15 months. GBM are organized hierarchically with a small number of glioma-initiating cells (GICs), responsible for therapy resistance and tumor recurrence, suggesting that targeting GICs could improve treatment response. ONC201 is a first-in-class anti-tumor agent with clinical efficacy in some forms of high-grade gliomas. Here we test its efficacy against GBM in combination with radiation.
Preoperative stereotactic ablative body radiotherapy with postoperative conventional irradiation of soft tissue sarcomas: Protocol overview with a preliminary safety report
S.N.NovikovaG.I.GaftonbM.A.EbertbE.A.FedosovaaJ.S.MelnikaG.V.ZinovevbI.G.GaftonbM.S.SinyachkinbS.V.Kanaeva
doi : 10.1016/j.radonc.2021.05.025
Volume 161, August 2021, Pages 126-131
Preoperative radiotherapy in patients with soft tissue sarcomas is characterized by important advantages: high precision of dose delivery, reduction of tumor volume and implantation potential, induction of immunologic response. Postoperative irradiation is associated with a reduced risk of complication, and a comprehensive radiotherapy planning in accordance with the pathologic report. Combination of pre- and postoperative irradiation gives the opportunity to use the best of both methods.
Neoadjuvant stereotactic ablative radiotherapy (SABR) for soft tissue sarcomas of the extremities
Elton Trigo TeixeiraLeiteRodrigo RamellaMunhozVeridiana Pires deCamargoLuiz Guilherme Cernaglia Aureliano deLimaDaniel Cesar SeguelRebolledoCarlos Eduardo BravinMaistroF?bio de FreitasBusnardoF?bio de OliveiraFerreiraJo?o VictorSalvajoliHeloisa de AndradeCarvalho
doi : 10.1016/j.radonc.2021.06.027
Volume 161, August 2021, Pages 222-229
Soft tissue sarcomas (STS) comprise a diverse group of mesenchymal malignancies that require multidisciplinary care. Although surgery remains the primary form of treatment for those with localized disease, radiation therapy (RT) is often incorporated either in the neo- or adjuvant setting. Given the development of modern RT techniques and alternative dosing schedules, stereotactic ablative radiotherapy (SABR) has emerged as a promising technique. However, the current role of SABR in the treatment of STS of the extremities remains uncertain.
Impact of covid-19 on patients in radiotherapy oncology departaments in Spain
Pilar M.Samper OtsaJoséZapatero Ortu?oaSaraPedraza Fern?ndezbEstherMayrata CanellascCarmenGonz?lez San SegundodMaiderCampo VargaseBego?aCaballerofM?nicaRamos AlbiacgGonzaloV?zquez MasedohBeatriz?lvareziSilviaRodr?guez VillalbajTeresaMu?oz Miguela?ezkPatriciaDiezhandino GarcialGemmaSanchomLauraGuzm?n G?meznJuanaTriperooMikel RicoRico OsespCarmenIba?ez VillosladaqAna Mar?a SolerSoler Rodr?guezrMar?a LuisaChustsAdrianaFondevilla SolertEva MariaLozano MartinuVirginiaMorillo MaciasvClaudioFuentes S?nchezwLauraTorrado MoyaxJes?sFern?ndez L?pezyJosep Mar?aSolézMarcosGuijarro Verd?aaMoisésMira FloresabAmadeoWalsacJoséExp?sito Hern?ndezad
doi : 10.1016/j.radonc.2021.06.001
Volume 161, August 2021, Pages 148-151
Skeletal muscle mass measurements using head and neck CT imaging in head and neck cancer patients
Remcode BreeaJustin E.SwartzaSandraBrilaNajibaChargiaIngeWegneraErnst JSmidb
doi : 10.1016/j.radonc.2021.05.029
Volume 161, August 2021, Pages 72-73
Association of prior radiation dose to the cardiopulmonary system with COVID-19 outcomes in patients with cancer
QuinceyLaPlanta1MariaThorb1NarekShaverdiana1Jacob Y.ShinaPhilipGilboaJiaLuocDaniel R.GomezaDaphna Y.Gelbluma
doi : 10.1016/j.radonc.2021.06.002
Volume 161, August 2021, Pages 115-117
Re: Prevalence and distribution of cervical lymph node metastases in HPV-positive and HPV-negative oropharyngeal squamous cell carcinoma. Radiother Oncol, 2021. 157: p. 122–129
GiuseppeSanguineti
doi : 10.1016/j.radonc.2021.05.011
Volume 161, August 2021, Pages 251-252
Reply to sanguineti regarding the manuscript untitled “Prevalence and distribution of cervical lymph node metastases in HPV-positive and HPV-negative oropharyngeal squamous cell carcinoma”
VincentGregoireLaurenceBauwens
doi : 10.1016/j.radonc.2021.05.009
Volume 161, August 2021, Page 253
Letter to the editor regarding the article “Photobiomodulation therapy for the prevention of acute radiation dermatitis in head and neck cancer patients (DERMISHEAD trial)” by Robijns et al. Radiat Oncol. 2021
OllyDonnellyaRebeccaGoranovabMichaelNugentc
doi : 10.1016/j.radonc.2021.06.007
Volume 161, August 2021, Page 254
Response to the Letter to the editor by Donnelly et al. regarding the article “Photobiomodulation therapy for the prevention of acute radiation dermatitis in head and neck cancer patients (DERMISHEAD trial)”
JolienRobijnsaJoyLodewijckxaStefanClaesbLeenVan BeverbLucPannekoekebSandrineCensabellabLoreBusséaDoraColsonaIrisKaminskiaVictoriaBrouxaSofiePutsaSofieVanmechelenaAnTimmermanscLeenNoébPaulBulensbMiekeGoversdAnneliesMaesbdJeroenMebisae
doi : 10.1016/j.radonc.2021.06.009
Volume 161, August 2021, Pages 255-256
A link between seasonality and radiation-related toxicity: The big time or time will tell?
ZuzannaNowickaaRobertBibikbRafa?StandocWojciechFendleradKonradStawiskiaBart?omiejTomasikad
doi : 10.1016/j.radonc.2021.06.010
Volume 161, August 2021, Pages 257-258
A link between seasonality and radiation-related toxicity: The big time or time will tell?: Response to Nowicka et al
OlgunElicinNikolaCihoric
doi : 10.1016/j.radonc.2021.06.008
Volume 161, August 2021, Page 259
Letter to the editor of radiotherapy and oncology regarding of the paper “Radiotherapy enhances uptake and efficacy of 90Y-cetuximab: A preclinical trial” by A Dietrich et al.
JiejianChenGuolongLiu
doi : 10.1016/j.radonc.2021.06.013
Volume 161, August 2021, Page 260
In reply to the Letter to the Editor by Chen and Lui regarding “Radiotherapy enhances uptake and efficacy of 90Y-cetuximab: A preclinical trial” by A Dietrich et al.
AntjeDietrichabcMichaelAndreeffdLydiaKoicefRalfBergmanngMaikSchubertgLenaSchreinercSteffenL?ckabhWiebkeSihvergRobertFreudenbergdSandraHeringiHans-JürgenPietzschgJ?rgSteinbachgjJ?rgKotzerkedkMichaelBaumannbceMechthildKrauseabcefh
doi : 10.1016/j.radonc.2021.06.014
Volume 161, August 2021, Pages 261-262
