دسترسی یکساله به بیش از ۵۰۰ ژورنال روز جهان موجود در سامانه
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Medical Adjuvants in the Treatment of Surgically Refractory Arteriovenous Malformations of the Head and Face: Case Report and Review of Literature
Govindarajan V. · Burks J.D. · Luther E.M. · Thompson J.W. · Starke R.M.
doi : 10.1159/000515168
Cerebrovasc Dis 2021;50:493–499
Arteriovenous malformations (AVMs) of the brain and face present unique challenges for clinicians. Cerebral AVMs may induce hemorrhage or form aneurysms, while facial AVMs can cause significant disfigurement and pain. Moreover, facial AVMs often draw blood supply from arteries providing critical blood flow to other important structures of the head which may make them impossible to treat curatively. Medical adjuvants may be an important consideration in the management of these patients.
Clinical Significance of Hyperdense Area after Endovascular Therapy in Patients with Acute Ischemic Stroke: A Systematic Review and Meta-Analysis
Jiang Q. · Hou J. · Ge J. · Huang Z. · Wang H. · Guo Z. · Cao Y. · You S. · Xiao G.
doi : 10.1159/000515410
Cerebrovasc Dis 2021;50:500–509
We performed a systematic review and meta-analysis to investigate the clinical significance of hyperdense area after thrombectomy in patients with acute ischemic stroke (AIS)
Plaque Longitudinal Heterogeneity in Morphology, Property, and Mechanobiology
Paritala P.K.a,b · Yarlagadda T.b · Mendieta J.B.a,b · Wang J.a,b · McGahan T.c · Lloyd T.d · Yarlagadda P.K.D.V.a,b · Li Z.a,b,e
doi : 10.1159/000515690
Cerebrovasc Dis 2021;50:510–519
The hemodynamic environment of an atherosclerotic plaque varies along the longitudinal direction. Investigating the changes in plaque morphology and its biomechanical environment along the longitudinal direction and their correlations will enhance our understanding of plaque progression and arterial remodeling.
Application of Mobile Stroke Unit in Prehospital Thrombolysis of Acute Stroke: Experience from China
Zhou T.a · Zhu L.a · Wang M.b · Li T.a · Li Y.a · Pei Q.c · Chen W.c · Zhao J.c · Wu H.c · Liu H.a · Li Z.a · He Y.a
doi : 10.1159/000514370
Cerebrovasc Dis 2021;50:520–525
Most patients cannot receive intravenous thrombolytic therapy in the early stage of stroke onset, and the application of mobile stroke unit (MSU) in prehospital intravenous thrombolytic therapy of acute stroke may change this situation. The first MSU in China was put into use in 2017. Herein, we aimed to explore the preliminary experience of MSU in prehospital thrombolysis of acute stroke.
The Effect of Aging and Small-Vessel Disease Burden on Hematoma Location in Patients with Acute Intracerebral Hemorrhage
Sakamoto Y. · Sato T. · Nito C. · Nishiyama Y. · Suda S. · Matsumoto N. · Aoki J. · Saito T. · Suzuki K. · Katano T. · Kimura K.
doi : 10.1159/000515411
Cerebrovasc Dis 2021;50:526–534
Intracerebral hemorrhage (ICH) is a devastating hemorrhagic event and is associated with high mortality or severe neurological sequelae. Age-associated differences in hematoma location for nonlobar ICH are not well known. The aims of the present study were to elucidate the relationship between age and hematoma location and to assess the differences in small-vessel disease (SVD) burden as a potential surrogate marker for longstanding hypertension among various hematoma locations.
Using Electronic Medical Records of Nursing Care to Characterize Constipation in Patients with Intracerebral Hemorrhage
Chen W.a,b · Zhao J.a · Li X.b · Wang X.a · Chen J.a · Zhang T.c · Ma L.a · Li D.d
doi : 10.1159/000515706
Cerebrovasc Dis 2021;50:535–542
Constipation is one of the common poststroke complications that directly affect the patients’ quality of life in patients with intracerebral hemorrhage (ICH), which has not been paid enough attention.
Real-World Field Performance of the Los Angeles Motor Scale as a Large Vessel Occlusion Screen: A Prospective Muticentre Study
Stead T.G.a · Banerjee P.b,c,d · Ganti L.b,c,d
doi : 10.1159/000516116
Cerebrovasc Dis 2021;50:543–550
The Los Angeles Motor Scale (LAMS) is a 3-item, 0-to-5-point motor stroke-deficit scale derived from the Los Angeles Prehospital Stroke Screen. We assessed the predictive validity (for interventions performed and discharge disposition) of the LAMS performed in the field by paramedics in a geographic region of over 5,200 km2, covering both rural and urban areas.
Bottlenecks in the Acute Stroke Care System during the COVID-19 Pandemic in Catalonia
Ramos-Pach?n A.a · Garc?a-Tornel ?.b · Mill?n M.a · Rib? M.c · Amaro S.d · Cardona P.e · Mart?-Fàbregas J.f · Roquer J.g · Silva Y.h · Ustrell X.i · Purroy F.j · G?mez-Choco M.k · Zaragoza-Brunet J.l · C?novas D.m · Krupinski J.n · Sala N.M.o · Palomeras E.p · Cocho D.q · Redondo L.r · Repullo C.s · Sanjurjo E.t · Carri?n D.u · L?pez M.v · Almendros M.C.w · Barcel? M.x · Monedero J.y · Catena E.z · Rybyeba M.A · Diaz G.B · Jiménez-Fàbrega X.C · Solà S.C · Hidalgo V.D · Pueyo M.J.E · Pérez de la Ossa N.F · Urra X.d · for the Catalan Stroke Code and Reperfusion Consortium (Cat-SCR)
doi : 10.1159/000516309
Cerebrovasc Dis 2021;50:551–559
The COVID-19 pandemic resulted in significant healthcare reorganizations, potentially striking standard medical care. We investigated the impact of the COVID-19 pandemic on acute stroke care quality and clinical outcomes to detect healthcare system’s bottlenecks from a territorial point of view.
Disparities between Asian and Non-Asian Thrombolyzed Acute Ischemic Stroke Patients in the Enhanced Control of Hypertension and Thrombolysis Stroke Trial
Chen C.a,b,c · Wang X.b · Chen X.b,c,f · Ouyang M.b · Sun L.c · Arima H.b,d · Robinson T.e · Lindley R.I.b,f · Chalmers J.b · Li G.a · Song L.b,c · Anderson C.S.b,c,f,g · for the ENCHANTED Investigators
doi : 10.1159/000516487
Cerebrovasc Dis 2021;50:560–566
As outcomes for acute ischemic stroke (AIS) vary according to clinical profile and management approaches, we aimed to determine disparities in clinical outcomes between Asian and non-Asian participants of the international, Enhanced Control of Hypertension and Thrombolysis Stroke study (ENCHANTED).
Deriving Place of Residence, Modified Rankin Scale, and EuroQol-5D Scores from the Medical Record for Stroke Survivors
Sucharew H.a,b · Kleindorfer D.c · Khoury J.C.a,b · Alwell K.d · Haverbusch M.d · Stanton R.d · Demel S.d · De Los Rios La Rosa F.d,e · Ferioli S.d · Jasne A.f · Mistry E.g · Moomaw C.J.d · Mackey J.h · Slavin S.i · Star M.j · Walsh K.d · Woo D.d · Kissela B.M.d
doi : 10.1159/000516571
Cerebrovasc Dis 2021;50:567–573
Mortality in Patients with Brainstem Cavernous Malformations
Velz J.a,b · Neidert M.C.a,b,c · Yang Y.a,b,c · Akeret K.a,b · Nakaji P.d · Regli L.a,b · Bozinov O.a,b,c
doi : 10.1159/000516909
Cerebrovasc Dis 2021;50:574–580
Brainstem cavernous malformations (BSCM)-associated mortality has been reported up to 20% in patients managed conservatively, whereas postoperative mortality rates range from 0 to 1.9%. Our aim was to analyze the actual risk and causes of BSCM-associated mortality in patients managed conservatively and surgically based on our own patient cohort and a systematic literature review.
Brain Infarction MRI Pattern in Stroke Patients with Intracardiac Thrombus
Trandafir C.a · Sandiramourty S.b · Laurent-Chabalier S.c · Ter Schiphorst A.a · Nguyen H.b · Wacongne A.a · Ricci J.-E.d · Pereira F.b · Thouvenot E.a,e · Renard D.a
doi : 10.1159/000515707
Cerebrovasc Dis 2021;50:581–587
Acute infarction patterns have been described in cardioembolic stroke, mainly with atrial fibrillation (AF) or patent foramen ovale. We aimed to analyse acute infarction magnetic resonance imaging (MRI) characteristics in stroke patients with intracardiac thrombus (ICT) compared with stroke patients with AF.
Advances in Understanding the Pathogenesis of Lacunar Stroke: From Pathology and Pathophysiology to Neuroimaging
Jiang S.a,b · Wu S.a · Zhang S.a · Wu B.a
doi : 10.1159/000516052
Cerebrovasc Dis 2021;50:588–596
Lacunar stroke (LS) accounts for about one-quarter of all acute ischemic strokes, represents an important marker of cerebral small vessel disease (CSVD), and has prognostic significance in terms of recurrent vascular events and vascular cognitive impairment. Our understanding of the etiology and pathogenesis of LS is largely based on the meticulous postmortem work of C. Miller Fisher in the late 1960s, with scarce subsequent pathological analysis of the “lacunar hypothesis” and no reliable approaches for direct in vivo imaging of the small intracranial vessels. The recent development of high-resolution MRI, which allows both large-vessel wall and perforating arteries to be imaged in one setting, provides the opportunity to advance understandings of the clinical mechanisms, imaging characteristics, and pathogenesis of LS. Given accumulating evidence of endothelial dysfunction and blood-brain-barrier disruption as early features of CSVD-related LS, advanced imaging may allow various underlying pathogenetic mechanisms to be defined and for better targeting of therapeutic approaches in LS. In this review, progress in understanding the pathogenesis of LS is outlined, covering pathology, pathophysiology, and imaging characteristics, with a focus toward future directions in the complex entity of LS.
Lipid Core Burden Index Assessed by Near-Infrared Spectroscopy of Symptomatic Carotid Plaques: Association with Magnetic Resonance T1-Weighted Imaging
Nakagawa I. · Kotsugi M. · Park H.S. · Yokoyama S. · Furuta T. · Nakase K. · Okamoto A. · Myouchin K. · Yamada S. · Nakase H.
doi : 10.1159/000516888
Cerebrovasc Dis 2021;50:597–604
Vulnerable plaques are a strong predictor of cerebrovascular ischemic events, and high lipid core plaques (LCPs) are associated with an increased risk of embolic infarcts during carotid artery stenting (CAS). Recent developments in magnetic resonance (MR) plaque imaging have enabled noninvasive assessment of carotid plaque vulnerability, and the lipid component and intraplaque hemorrhage (IPH) are visible as high signal intensity areas on T1-weighted MR images. Recently, catheter-based near-infrared spectroscopy (NIRS) has been shown to accurately distinguish LCPs without IPH. This study aimed to determine whether the results of assessment of high LCPs by catheter-based NIRS correlate with the results of MR plaque imaging.
Secondary Prevention of Stroke: Study Protocol for a Telehealth-Delivered Physical Activity and Diet Pilot Randomized Trial (ENAbLE-Pilot)
English C.a,b,c,d · Attia J.R.e · Bernhardt J.c · Bonevski B.b,e · Burke M.b · Galloway M.a,b,c,d · Hankey G.J.f · Janssen H.a,b,c,d,g · Kuys S.h · Lindley R.I.i · Lynch E.c,d,j · Marsden D.L.a,b,g · Nilsson M.b,c,d,e · Ramage E.R.a,b,c,d,k · Said C.M.k,l · Spratt N.J.b,c,m,n · Zacharia K.a,b,o · Macdonald-Wicks L.a,o · Patterson A.a,o
doi : 10.1159/000515689
Cerebrovasc Dis 2021;50:605–611
Increasing physical activity (PA) and improving diet quality are opportunities to improve secondary stroke prevention, but access to appropriate services is limited. Interventions co-designed with stroke survivors and delivered by telehealth are a potential solution.
The Influence of the COVID-19 Pandemic in an Emergency Department for Cardio-Cerebrovascular Disease Visits in Taiwan
Liu T.-Y.a · Tsai M.-T.a · Cheng F.-J.a · Cheng C.-Y.a,b
doi : 10.1159/000515691
Cerebrovasc Dis 2021;50:612–614
