Walter C Willett, Frank B Hu, Eric B Rimm, Meir J Stampfer
doi : 10.1093/ajcn/nqab079
The American Journal of Clinical Nutrition, Volume 114, Issue 2, August 2021, Pages 401–404
Elizabeth J Mayer-Davis, Timothy S Naimi, Richard D Mattes
doi : 10.1093/ajcn/nqab092
The American Journal of Clinical Nutrition, Volume 114, Issue 2, August 2021, Pages 405–406
Kenneth H Brown, Christine M McDonald, K Ryan Wessells, Sonja Y Hess
doi : 10.1093/ajcn/nqab159
The American Journal of Clinical Nutrition, Volume 114, Issue 2, August 2021, Pages 407–409
Michele R Forman
doi : 10.1093/ajcn/nqab166
The American Journal of Clinical Nutrition, Volume 114, Issue 2, August 2021, Pages 410–411
Katarina Bälter
doi : 10.1093/ajcn/nqab167
The American Journal of Clinical Nutrition, Volume 114, Issue 2, August 2021, Pages 412–413
Xiaobin Wang
doi : 10.1093/ajcn/nqab168
The American Journal of Clinical Nutrition, Volume 114, Issue 2, August 2021, Pages 414–415
Deirdre K Tobias, Martín Lajous
doi : 10.1093/ajcn/nqab169
The American Journal of Clinical Nutrition, Volume 114, Issue 2, August 2021, Pages 416–417
Dong Hoon Lee, Edward L Giovannucci
doi : 10.1093/ajcn/nqab127
The American Journal of Clinical Nutrition, Volume 114, Issue 2, August 2021, Pages 418–419
Charlene W Compher
doi : 10.1093/ajcn/nqab171
The American Journal of Clinical Nutrition, Volume 114, Issue 2, August 2021, Pages 420–421
Nair Tavares Milhem Ygnatios, Cesar de Oliveira, Juliana Vaz de Melo Mambrini, Fabíola Bof de Andrade, Maria Fernanda Lima-Costa, Juliana Lustosa Torres
doi : 10.1093/ajcn/nqab060
The American Journal of Clinical Nutrition, Volume 114, Issue 2, August 2021, Pages 422–428
Brazil and England are 2 countries at different stages in their demographic, epidemiological, and nutritional transitions and with distinct socioeconomic and politic contexts, but with similar universal health systems. We aimed to examine disability and its association with objective anthropometric indicators of nutritional status, including BMI, waist circumference, and waist-to-height ratio, comparing older Brazilian and English adults.
Xiaona Zhang, Yushan Wang, Wen Liu, Tao Wang, Lijing Wang, Ling Hao, Mengwei Ju, Rong Xiao
doi : 10.1093/ajcn/nqab078
The American Journal of Clinical Nutrition, Volume 114, Issue 2, August 2021, Pages 429–440
Diet, the gut microbiota, and microRNAs (miRNAs) have been recognized as factors possibly influencing the pathogenesis of Alzheimer's disease. However, the combined role of diet, the gut microbiota, and miRNAs in mild cognitive impairment (MCI) has not been extensively investigated.
Ilka Ratjen, Janna Enderle, Greta Burmeister, Manja Koch, Ute Nöthlings, Jochen Hampe, Wolfgang Lieb
doi : 10.1093/ajcn/nqab061
The American Journal of Clinical Nutrition, Volume 114, Issue 2, August 2021, Pages 441–449
Plant-rich diets are associated with lower cardiometabolic risks and longer survival in the general population, but their association with mortality in cancer survivors is still unclear.
You Wu, Ruyi Huang, Molin Wang, Leslie Bernstein, Traci N Bethea, Chu Chen, Yu Chen, A Heather Eliassen, Neal D Freedman, Mia M Gaudet, Gretchen L Gierach, Graham G Giles, Vittorio Krogh, Susanna C Larsson, Linda M Liao, Marjorie L McCullough, Anthony B Miller, Roger L Milne, Kristine R Monroe, Marian L Neuhouser, Julie R Palmer, Anna Prizment, Peggy Reynolds, Kim Robien, Thomas E Rohan, Sven Sandin, Norie Sawada, Sabina Sieri, Rashmi Sinha, Rachael Z Stolzenberg-Solomon, Shoichiro Tsugane, Piet A van den Brandt, Kala Visvanathan, Elisabete Weiderpass, Lynne R Wilkens, Walter C Willett, Alicja Wolk, Anne Zeleniuch-Jacquotte, Regina G Ziegler, Stephanie A Smith-Warner
doi : 10.1093/ajcn/nqab097
The American Journal of Clinical Nutrition, Volume 114, Issue 2, August 2021, Pages 450–461
Epidemiologic studies examining the relations between dairy product and calcium intakes and breast cancer have been inconclusive, especially for tumor subtypes.
Tingting Huang, Alexander Ploner, Ellen T Chang, Qing Liu, Yonglin Cai, Zhe Zhang, Guomin Chen, Qihong Huang, Shanghang Xie, Sumei Cao ... Show more
doi : 10.1093/ajcn/nqab114
The American Journal of Clinical Nutrition, Volume 114, Issue 2, August 2021, Pages 462–471
Dietary factors, such as consumption of preserved foods, fresh vegetables, and fruits, have been linked to the risk of nasopharyngeal carcinoma (NPC). However, little is known about associations between dietary patterns and the risk of NPC in NPC-endemic areas.
Mingzhu Cai, Bowen Dou, Jennifer E Pugh, Aaron M Lett, Gary S Frost
doi : 10.1093/ajcn/nqab098
The American Journal of Clinical Nutrition, Volume 114, Issue 2, August 2021, Pages 472–487
Starchy foods can have a profound effect on metabolism. The structural properties of starchy foods can affect their digestibility and postprandial metabolic responses, which in the long term may be associated with the risk of type 2 diabetes and obesity.
Donna L Thorpe, W Lawrence Beeson, Raymond Knutsen, Gary E Fraser, Synnove F Knutsen
doi : 10.1093/ajcn/nqab095
The American Journal of Clinical Nutrition, Volume 114, Issue 2, August 2021, Pages 488–495
Concerns regarding the adequacy of vegetarian diets with respect to fracture risk continue.
Yuanjie Pang, Jun Lv, Christiana Kartsonaki, Canqing Yu, Yu Guo, Yiping Chen, Ling Yang, Iona Y Millwood, Robin G Walters, Sisi Wang, Junshi Chen, Zhengming Chen, Liming Li
doi : 10.1093/ajcn/nqab099
The American Journal of Clinical Nutrition, Volume 114, Issue 2, August 2021, Pages 496–504
Metabolic risk factors have been shown to be associated with severe liver disease (SLD) in Chinese populations. However, there is limited evidence on the combined impact of these factors, or the genetic variants associated with SLD.
Jonathan C Wells, Peter S Davies, Mark Hopkins, John E Blundell
doi : 10.1093/ajcn/nqab067
The American Journal of Clinical Nutrition, Volume 114, Issue 2, August 2021, Pages 505–514
Recent work has challenged the long-held assumption that appetite functions to maintain stable body mass and fat mass (FM), suggesting instead that appetite matches food intake to energy expenditure and its correlate, fat-free mass (FFM). Whether this scenario applies to young infants, in chronic positive energy balance, remains unknown.
Anna Strid, Ingegerd Johansson, Marta Bianchi, Ulf Sonesson, Elinor Hallström, Bernt Lindahl, Anna Winkvist
doi : 10.1093/ajcn/nqab073
The American Journal of Clinical Nutrition, Volume 114, Issue 2, August 2021, Pages 515–529
Diets combining adequate nutritional quality and low climate impact are highly needed for human and planet health.
Patricia Eustachio Colombo, James Milner, Pauline F D Scheelbeek, Anna Taylor, Alexandr Parlesak, Thomas Kastner, Owen Nicholas, Liselotte S Elinder, Alan D Dangour, Rosemary Green
doi : 10.1093/ajcn/nqab076
The American Journal of Clinical Nutrition, Volume 114, Issue 2, August 2021, Pages 530–539
Fruit and vegetable consumption in the United Kingdom is currently well below recommended levels, with a significant associated public health burden. The United Kingdom has committed to reducing its carbon emissions to net zero by 2050, and this transition will require shifts towards plant-based diets.
Pi-i D Lin, Andres Cardenas, Sheryl L Rifas-Shiman, Marie-France Hivert, Tamarra James-Todd, Chitra Amarasiriwardena, Robert O Wright, Mohammad L Rahman, Emily Oken
doi : 10.1093/ajcn/nqab088
The American Journal of Clinical Nutrition, Volume 114, Issue 2, August 2021, Pages 540–549
Dietary sources of metals are not well established among pregnant women in the United States.
Timothy B Sulser, Robert H Beach, Keith D Wiebe, Shahnila Dunston, Naomi K Fukagawa
doi : 10.1093/ajcn/nqab101
The American Journal of Clinical Nutrition, Volume 114, Issue 2, August 2021, Pages 550–563
Climate change presents an increasing challenge for food-nutrition security. Nutrition metrics calculated from quantitative food system projections can help focus policy actions.
Ethendhar Rajendiran, Benoît Lamarche, Yongbo She, Vanu Ramprasath, Peter Eck, Didier Brassard, Iris Gigleux, Emile Levy, Angelo Tremblay, Patrick Couture, James D House, Peter J H Jones, Charles Desmarchelier
doi : 10.1093/ajcn/nqab064
The American Journal of Clinical Nutrition, Volume 114, Issue 2, August 2021, Pages 564–577
Blood lipid concentrations display high interindividual variability in response to dietary interventions, partly due to genetic factors. Existing studies have focused on single nucleotide polymorphisms (SNPs) analyzed individually, which only explain a limited fraction of the variability of these complex phenotypes.
Ching-Ti Liu, David Karasik, Hanfei Xu, Yanhua Zhou, Kerry Broe, L Adrienne Cupples, Lisette Cpgm de Groot, Annelies Ham, Marian T Hannan, Yi-Hsiang Hsu, Paul Jacques, Robert R McLean, Ligi Paul, Jacob Selhub, Katerina Trajanoska, Nathalie van der Velde, Natasja van Schoor, Douglas P Kiel
doi : 10.1093/ajcn/nqab093
The American Journal of Clinical Nutrition, Volume 114, Issue 2, August 2021, Pages 578–587
Elevated plasma homocysteine has been found to be associated with an increased risk of osteoporosis, especially hip and vertebral fractures. The plasma concentration of homocysteine is dependent on the activities of several B vitamin–dependent enzymes, such as methylenetetrahydrofolate reductase (MTHFR), methionine synthase (MTR), methionine synthase reductase (MTRR), and cystathionine ?-synthase (CBS).
Seoyoon Cho, Ziliang Zhu, Tengfei Li, Kristine Baluyot, Brittany R Howell, Heather C Hazlett, Jed T Elison, Jonas Hauser, Norbert Sprenger, Di Wu, Weili Lin
doi : 10.1093/ajcn/nqab103
The American Journal of Clinical Nutrition, Volume 114, Issue 2, August 2021, Pages 588–597
Genetic polymorphisms leading to variations in human milk oligosaccharide (HMO) composition have been reported. Alpha-Tetrasaccharide (A-tetra), an HMO, has been shown to only be present (>limit of detection; A-tetra+) in the human milk (HM) of women with blood type A, suggesting genetic origins determining the presence or absence (A-tetra-) of A-tetra in HM.
Bruna Z Reis, Alan L Fernandes, Lucas P Sales, Mayara D Santos, Caroline C dos Santos, Ana J Pinto, Karla F Goessler, Andre S Franco, Camila S C Duran, Carla B R Silva, Marina B Macêdo, Henrique H H Dalmolin, Janaína Baggio, Guilherme G M Balbi, Leila Antonangelo, Valeria F Caparbo, Bruno Gualano, Igor H Murai, Rosa M R Pereira
doi : 10.1093/ajcn/nqab151
The American Journal of Clinical Nutrition, Volume 114, Issue 2, August 2021, Pages 598–604
Vitamin D acts as a mediator in the immune system regulating antiviral mechanisms and inflammatory processes. Vitamin D insufficiency has been suggested as a potential risk factor for severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infection, although its impact on the prognosis of hospitalized patients with coronavirus disease 2019 (COVID-19) remains unclear.
Kari K Koponen, Aaro Salosensaari, Matti O Ruuskanen, Aki S Havulinna, Satu Männistö, Pekka Jousilahti, Joonatan Palmu, Rodolfo Salido, Karenina Sanders, Caitriona Brennan, Gregory C Humphrey, Jon G Sanders, Guillaume Meric, Susan Cheng, Michael Inouye, Mohit Jain, Teemu J Niiranen, Liisa M Valsta, Rob Knight, Veikko V Salomaa
doi : 10.1093/ajcn/nqab077
The American Journal of Clinical Nutrition, Volume 114, Issue 2, August 2021, Pages 605–616
Diet has a major influence on the human gut microbiota, which has been linked to health and disease. However, epidemiological studies on associations of a healthy diet with the microbiota utilizing a whole-diet approach are still scant.
Susan M Smith, Manjot S Virdee, Judith K Eckerle, Kristin E Sandness, Michael K Georgieff, Christopher J Boys, Steven H Zeisel, Jeffrey R Wozniak
doi : 10.1093/ajcn/nqab081
The American Journal of Clinical Nutrition, Volume 114, Issue 2, August 2021, Pages 617–627
The essential nutrient choline provides one-carbon units for metabolite synthesis and epigenetic regulation in tissues including brain. Dietary choline intake is often inadequate, and higher intakes are associated with improved cognitive function.
Josine M Stuber, Jody C Hoenink, Joline W J Beulens, Joreintje D Mackenbach, Jeroen Lakerveld
doi : 10.1093/ajcn/nqab057
The American Journal of Clinical Nutrition, Volume 114, Issue 2, August 2021, Pages 628–637
Nudging and salient pricing are promising strategies to promote healthy food purchases, but it is possible their effects differ across food groups.
Raghu Pullakhandam, Praween K Agrawal, Rajini Peter, Santu Ghosh, G Bhanuprakash Reddy, Bharati Kulkarni, Tinku Thomas, Anura V Kurpad, Harshpal S Sachdev, Akash Porwal, Nizamuddin Khan, Sowmya Ramesh, Rajib Acharya, Avina Sarna, Umesh Kapil, Hemalatha Rajkumar, Arjan De Wagt, Sila Deb, Robert Johnston
doi : 10.1093/ajcn/nqab066
The American Journal of Clinical Nutrition, Volume 114, Issue 2, August 2021, Pages 638–648
It is thought that there is a high risk of zinc deficiency in India, but there are no representative national estimates.
Szu-Yun Wu, Nai-Hua Yeh, Hsing-Yi Chang, Chi-Fen Wang, Shu-Yi Hung, Shin-Jiuan Wu, Wen-Harn Pan
doi : 10.1093/ajcn/nqab070
The American Journal of Clinical Nutrition, Volume 114, Issue 2, August 2021, Pages 649–660
Emerging evidence suggests that a dietary protein intake higher than the current recommended dietary allowance of 0.8 g/kg body weight (BW)/d may be needed to maintain optimal muscle mass, strength, and function in older adults. However, defining optimal protein intake in this age group remains a challenge.
Gregory Haber, Joshua Sampson, Katherine M Flegal, Barry Graubard
doi : 10.1093/ajcn/nqab074
The American Journal of Clinical Nutrition, Volume 114, Issue 2, August 2021, Pages 661–668
Several studies have assessed the relation of body composition to health outcomes by using values of fat and lean mass that were not measured but instead were predicted from anthropometric variables such as weight and height. Little research has been done on how substituting predicted values for measured covariates might affect analytic results.
Irene van Woerden, Devon C Payne-Sturges, Corrie M Whisner, Meg Bruening
doi : 10.1093/ajcn/nqab080
The American Journal of Clinical Nutrition, Volume 114, Issue 2, August 2021, Pages 669–682
Given policy regulations restricting bisphenol A (BPA) in food-related products, and consumer concerns about adverse health effects, newer bisphenols such as bisphenol F (BPF) and bisphenol S (BPS) have been developed. Exposure to BPA has been linked to dietary behaviors and poor health outcomes.
Namrata Sanjeevi, Jeanne H Freeland-Graves, Prageet K Sachdev
doi : 10.1093/ajcn/nqab082
The American Journal of Clinical Nutrition, Volume 114, Issue 2, August 2021, Pages 683–689
Supplemental Nutrition Assistance Program (SNAP) disenrollment among income-eligible households could limit their ability to access food.
Yu-Han Chiu, Jorge E Chavarro, Barbra A Dickerman, JoAnn E Manson, Kenneth J Mukamal, Kathryn M Rexrode, Eric B Rimm, Miguel A Hernán
doi : 10.1093/ajcn/nqab100
The American Journal of Clinical Nutrition, Volume 114, Issue 2, August 2021, Pages 690–703
Because randomized trials of sustained dietary changes are sometimes impractical for long-term outcomes, the explicit emulation of a (hypothetical) target trial using observational data may be an important tool for nutritional epidemiology.
Cheng Luo, Hongjie Liu, Xiaoqian Wang, Lili Xia, Hanqiu Huang, Xiaoling Peng, Chao Xia, Liegang Liu
doi : 10.1093/ajcn/nqab102
The American Journal of Clinical Nutrition, Volume 114, Issue 2, August 2021, Pages 704–712
Several individual studies have shown that circulating levels of odd-chain SFAs and very-long-chain SFAs (VLSFAs) may have beneficial effects, but the results are mixed. While the dietary and metabolic factors that may influence VLSFAs are not well-known, a previous study observed associations of VLSFA concentrations with variants in serine palmitoyl-transferase long-chain base subunit 3 (SPTLC3) gene.
Joseph Lindquist, Diana M Thomas, Dusty Turner, Jeanne Blankenship, Theodore K Kyle
doi : 10.1093/ajcn/nqab119
The American Journal of Clinical Nutrition, Volume 114, Issue 2, August 2021, Pages 713–720
The Administrative Procedure Act of 1946 guarantees the public an opportunity to view and comment on the 2020 Dietary Guidelines as part of the policymaking process. In the past, public comments were submitted by postal mail or public hearings. The convenience of public comment through the Internet has generated increased comment volume, making manual analysis challenging.
Natasha Tasevska, Virag Sagi-Kiss, Susana A Palma-Duran, Brian Barrett, Matthew Chaloux, John Commins, Diane M O'Brien, Carol S Johnston, Douglas Midthune, Victor Kipnis, Laurence S Freedman
doi : 10.1093/ajcn/nqab158
The American Journal of Clinical Nutrition, Volume 114, Issue 2, August 2021, Pages 721–730
Developing approaches for the objective assessment of sugars intake in population research is crucial for generating reliable disease risk estimates, and evidence-based dietary guidelines. Twenty-four-hour urinary sucrose and fructose (24uSF) was developed as a predictive biomarker of total sugars intake based on 3 UK feeding studies, yet its performance as a biomarker of total sugars among US participants is unknown.
Nina Kaegi-Braun, MD, Pascal Tribolet, RD, Annic Baumgartner, MD, Rebecca Fehr, RD, Valerie Baechli, RD, Martina Geiser, RD, Manuela Deiss, RD, Filomena Gomes, PhD, Alexander Kutz, MD, MSc, Claus Hoess, MD, Vojtech Pavlicek, MD, Sarah Schmid, RD, Stefan Bilz, MD, Sarah Sigrist, MD, Michael Brändle, Carmen Benz, RD, Christoph Henzen, Robert Thomann, MD, Jonas Rutishauser, Drahomir Aujesky, Nicolas Rodondi, Jacques Donzé, Zeno Stanga, Beat Mueller, Philipp Schuetz, MPH
doi : 10.1093/ajcn/nqab042
The American Journal of Clinical Nutrition, Volume 114, Issue 2, August 2021, Pages 731–740
Disease-related malnutrition is associated with loss of muscle mass and impaired functional status. Handgrip strength (HGS) has been proposed as an easy-to-use tool to assess muscle strength in clinical practice.
Laïla Baratali, Marie Mean, Pedro Marques-Vidal
doi : 10.1093/ajcn/nqab069
The American Journal of Clinical Nutrition, Volume 114, Issue 2, August 2021, Pages 741–751
Whether genetic background and/or dietary behaviors influence weight gain in middle-aged subjects is debated.
Danyelle M Liddle, Xinjie Lin, Liam C Cox, Emily M Ward, Rufaida Ansari, Amanda J Wright, Lindsay E Robinson
doi : 10.1093/ajcn/nqab094
The American Journal of Clinical Nutrition, Volume 114, Issue 2, August 2021, Pages 752–763
Obesity-associated low-grade inflammation contributes to the development of cardiovascular disease (CVD). Apples are rich in anti-inflammatory bioactives including polyphenols and fiber.
Sonja Yokum, Cara Bohon, Elliot Berkman, Eric Stice
doi : 10.1093/ajcn/nqab096
The American Journal of Clinical Nutrition, Volume 114, Issue 2, August 2021, Pages 764–779
Functional MRI (fMRI) tasks are increasingly being used to advance knowledge of the etiology and maintenance of obesity and eating disorders. Thus, understanding the test-retest reliability of BOLD signal contrasts from these tasks is important.
Teng Xu, Xu Zhang, Yuning Liu, Hao Wang, Junjie Luo, Yongting Luo, Peng An
doi : 10.1093/ajcn/nqab068
The American Journal of Clinical Nutrition, Volume 114, Issue 2, August 2021, Pages 780–793
The iron-chelating activities of polyphenols raise concern whether there is a risk of iron deficiency or anemia induced by polyphenol supplementation. Results from clinical trials regarding the effects of polyphenol supplementation on iron status and erythropoiesis are inconclusive.
Kristy L Gray, Peter M Clifton, Jennifer B Keogh
doi : 10.1093/ajcn/nqab058
The American Journal of Clinical Nutrition, Volume 114, Issue 2, August 2021, Pages 794–803
Weight loss after gestational diabetes (GDM) can prevent or delay the onset of type 2 diabetes. Intermittent energy restriction (IER) may offer an alternative to continuous energy restriction (CER) for weight loss.
Melissa S Bauserman, Carla M Bann, K Michael Hambidge, Ana L Garces, Lester Figueroa, Jamie L Westcott, Jackie K Patterson, Elizabeth M McClure, Vanessa R Thorsten, Sumera Ali Aziz, Sarah Saleem, Robert L Goldenberg, Richard J Derman, Veena Herekar, Manjunath Somannavar, Marion W Koso-Thomas, Adrien L Lokangaka, Antoinette K Tshefu, Nancy F Krebs, Carl L Bose, The Women First Preconception Trial Study Group
doi : 10.1093/ajcn/nqab086
The American Journal of Clinical Nutrition, Volume 114, Issue 2, August 2021, Pages 804–812
Adequate gestational weight gain (GWG) is essential for healthy fetal growth. However, in low- and middle-income countries, where malnutrition is prevalent, little information is available about GWG and how it might be modified by nutritional status and interventions.
Yeyi Zhu, Monique M Hedderson, Susan D Brown, Sylvia E Badon, Juanran Feng, Charles P Quesenberry, Assiamira Ferrara
doi : 10.1093/ajcn/nqab089
The American Journal of Clinical Nutrition, Volume 114, Issue 2, August 2021, Pages 813–821
Preterm birth (PTB) remains a leading cause of neonatal mortality and long-term morbidity. Individual factors have been linked to PTB risk. The impact of a healthy lifestyle, with multiple modifiable prenatal factors, remains unknown.
Amar Laila
doi : 10.1093/ajcn/nqab230
The American Journal of Clinical Nutrition, Volume 114, Issue 2, August 2021, Pages 822–823
Marit Kolby Zinöcker, Karianne Svendsen, Simon Nitter Dankel
doi : 10.1093/ajcn/nqab231
The American Journal of Clinical Nutrition, Volume 114, Issue 2, August 2021, Pages 823–824
Mary-Ellen Harper, Ruth McPherson, Robert Dent
doi : 10.1093/ajcn/nqab213
The American Journal of Clinical Nutrition, Volume 114, Issue 2, August 2021, Pages 824–825
doi : 10.1093/ajcn/nqab208
The American Journal of Clinical Nutrition, Volume 114, Issue 2, August 2021, Pages 826–827
doi : 10.1093/ajcn/nqab227
The American Journal of Clinical Nutrition, Volume 114, Issue 2, August 2021, Page 827
doi : 10.1093/ajcn/nqab240
The American Journal of Clinical Nutrition, Volume 114, Issue 2, August 2021, Page 827
doi : 10.1093/ajcn/nqab248
The American Journal of Clinical Nutrition, Volume 114, Issue 2, August 2021, Page 827
doi : 10.1093/ajcn/nqab257
The American Journal of Clinical Nutrition, Volume 114, Issue 2, August 2021, Page 828
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