Cornea




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سفارش

A Close Look at the Clinical Efficacy of Rho-Associated Protein Kinase Inhibitor Eye Drops for Fuchs Endothelial Corneal Dystrophy

Kinoshita, Shigeru MD, PhD*; Colby, Kathryn A. MD, PhD†; Kruse, Friedrich E. MD, PhD‡

doi : 10.1097/ICO.0000000000002642

October 2021 - Volume 40 - Issue 10 - p 1225-1228

The current understanding on the clinical efficacy of Rho-associated protein kinase (ROCK) inhibitor for treating Fuchs endothelial corneal dystrophy is summarized to clarify whether the “off-label” ROCK-inhibitor eye-drop application are appropriate. ROCK-inhibitor eye drops may eventually be deemed a cutting-edge therapy for Fuchs endothelial corneal dystrophy patients with acute corneal endothelial defect.

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Supply and Demand of Domestic Corneal Tissue and Its Implications on Export Potential—Using Australia as an Example

Machin, Heather RN, MBA*; Buckland, Lisa GCQM†; Georges, Pierre MScMed‡; Ghabcha, Mona BMedSc‡; Golding-Holbrook, Tamme BMSc, SCEB§; Leighton, Candice BSc, CTBS¶; Mackey, Adrienne BSc, GCPH?,**; Weinel, Luke BHSc (Hons)§; Whiting, Victoria BApplSci¶; Sutton, Gerard MBBS, FRANZCO PhD‡,††,‡‡; Baird, Paul N. PhD**

doi : 10.1097/ICO.0000000000002599

October 2021 - Volume 40 - Issue 10 - p 1229-1235

Corneal tissue importation is only possible if another country is able to export corneas without impacting its own domestic demand. Currently, there is little evidence to indicate whether export nations have such surplus capacity and in a position to export. To explore this concept, we examined our nation, Australia, which is reported to routinely decline donations because of its ability to meet domestic corneal transplant demand. Our research offers insights and opportunities for Australia and other nations to evaluate their domestic and international supply and allocation of corneal tissue in this space.

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Sutured Custom Foldable Silicone Artificial Iris Implantation Combined With Intraocular Lens Implantation and Penetrating Keratoplasty: Safety and Efficacy Outcomes

Bonnet, Clemence MD*,†; Vazirnia, Parsia*; Deng, Sophie X. MD, PhD*; Aldave, Anthony J. MD*; Miller, Kevin M. MD*

doi : 10.1097/ICO.0000000000002564

October 2021 - Volume 40 - Issue 10 - p 1236-1247

To assess safety and efficacy outcomes of sutured custom silicone artificial iris and intraocular lens implantation combined with penetrating keratoplasty (triple procedure).

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Efficacy of Long-term Use of 0.3% Sodium Hyaluronate Eye Drops for Traumatic Corneal Abrasion: A Randomized Controlled, Pilot Trial

Wei, Menghuan MD Candidate; Zou, Yingshi MD Candidate; Duan, Fang PhD; Ding, Xiaohu PhD; Zhuang, Jiejie BSc; Deng, Jiayu BSc; Yuan, Zhaohui PhD

doi : 10.1097/ICO.0000000000002625

October 2021 - Volume 40 - Issue 10 - p 1248-1252

Traumatic corneal abrasion (TCA) causes damage to both corneal epithelium and the underlying hemidesmosomal junctions. Delayed recovery of hemidesmosomal junctions causes symptomatic episodes. However, there is no recommended treatment for recovery of hemidesmosomal junctions, indicating that a blank period exists in TCA treatment. In this study, the efficacy of long-term use of sodium hyaluronate on recovery of hemidesmosomal junctions during the blank period in TCA healing was investigated.

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Outcomes of Pseudophakic, Phakic, and Triple DMEK

Moshiri, Isabella MD; Karimi-Golkar, Damian; Schrittenlocher, Silvia MD; Cursiefen, Claus MD, PhD; Bachmann, Björn MD, PhD

doi : 10.1097/ICO.0000000000002723

October 2021 - Volume 40 - Issue 10 - p 1253-1257

To evaluate the outcome of phakic and pseudophakic eyes treated by Descemet membrane endothelial keratoplasty (DMEK) versus DMEK combined with cataract surgery (triple DMEK).

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Endophthalmitis in Eyes With the Boston Type I Keratoprosthesis: Incidence, Recurrence, Risk Factors, and Outcomes

Bostan, Cristina MD, MSc*; Nayman, Taylor MD*; Szigiato, Andrei-Alexandru MD*; Morfeq, Hussein MD*,†; Harissi-Dagher, Mona MD, FRCSC*

doi : 10.1097/ICO.0000000000002641

October 2021 - Volume 40 - Issue 10 - p 1258-1266

To determine the incidence and recurrence of Boston type I keratoprosthesis (KPro)-associated endophthalmitis, and its microbiological profile, risk factors, and outcomes.

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Corneal Edema Visualization With Optical Coherence Tomography Using Deep Learning: Proof of Concept

Zéboulon, Pierre MD*; Ghazal, Wassim MD*; Gatinel, Damien MD, PhD*,†

doi : 10.1097/ICO.0000000000002640

October 2021 - Volume 40 - Issue 10 - p 1267-1275

Optical coherence tomography (OCT) is essential for the diagnosis and follow-up of corneal edema, but assessment can be challenging in minimal or localized edema. The objective was to develop and validate a novel automated tool to detect and visualize corneal edema with OCT.

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Optical Quality in Keratoconus Is Associated With Corneal Biomechanics

Shugyo, Akiko MD*; Koh, Shizuka MD, PhD*,†; Inoue, Ryota MS†,‡; Ambrósio, Renato Jr MD, PhD§; Miki, Atsuya MD, PhD*,†; Maeda, Naoyuki MD, PhD*; Nishida, Kohji MD, PhD*,¶

doi : 10.1097/ICO.0000000000002631

October 2021 - Volume 40 - Issue 10 - p 1276-1281

To evaluate the correlations between corneal biomechanical indices from dynamic Scheimpflug assessment and optical quality assessed as higher-order aberrations (HOAs) using a Hartmann–Shack ocular wavefront sensor in patients with keratoconus (KC).

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Four-Year Survival Comparison of Endothelial Keratoplasty Techniques in Patients With Previous Glaucoma Surgery

Alshaker, Sara MD*; Mimouni, Michael MD*; Batawi, Hatim MD*; Cohen, Eyal MD*; Trinh, Tanya MBBS, FRANZCO*; Santaella, Gisella MD*; Chan, Clara C. MD, FACS, FRCSC*; Slomovic, Allan R. MD, FRCSC*; Rootman, David S. MD, FRCSC*; Sorkin, Nir MD*,†

doi : 10.1097/ICO.0000000000002585

October 2021 - Volume 40 - Issue 10 - p 1282-1289

To compare 4-year survival outcomes of Descemet membrane endothelial keratoplasty (DMEK) and Descemet-stripping automated endothelial keratoplasty (DSAEK) in eyes with previous glaucoma surgery.

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A Water-free 0.1% Cyclosporine A Solution for Treatment of Dry Eye Disease: Results of the Randomized Phase 2B/3 ESSENCE Study

Sheppard, John D. MD*; Wirta, David L. MD†; McLaurin, Eugene MD‡; Boehmer, Blair E. MD§; Ciolino, Joseph B. MD¶; Meides, Alice S. PhD?; Schlüter, Thomas PhD?; Ousler, George W.**; Usner, Dale PhD††; Krösser, Sonja PhD?

doi : 10.1097/ICO.0000000000002633

October 2021 - Volume 40 - Issue 10 - p 1290-1297

To assess the efficacy, safety, and tolerability of a topical water-free cyclosporine A formulation (CyclASol 0.1% ophthalmic solution) in comparison with vehicle for the treatment of dry eye disease (DED).

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Infectious Keratitis After Boston Type 1 Keratoprosthesis Implantation

Ghaffari, Reza MD*,†; Bonnet, Clemence MD*,‡; Yung, Madeline MD*; Bostan, Cristina MD, MSc§; Harissi-Dagher, Mona MD§; Aldave, Anthony J. MD*

doi : 10.1097/ICO.0000000000002649

October 2021 - Volume 40 - Issue 10 - p 1298-1308

To identify the incidence, risk factors, and outcomes of infectious keratitis after Boston type 1 keratoprosthesis (kpro) implantation.

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Influence of Reading on Smartphone Screens on Visual Optical Quality Metrics and Tear Film Stability

Bettach, Emmanuel MD*,†; Zadok, David MD*,†; Abulafia, Adi MD*,†; Shoshani, Avi OD*,†; Ghebali, Rony A. MSc†; Weill, Yishay MD*,†; Smadja, David MD*,†

doi : 10.1097/ICO.0000000000002656

October 2021 - Volume 40 - Issue 10 - p 1309-1315

To evaluate the impact of a prolonged reading session on a smartphone screen on optical quality metrics and tear film stability.

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Patient-Reported Outcomes After Corneal Transplantation

Dunbar, Grace E. MD*; Titus, Michael CEBT†; Stein, Joshua D. MD, MS, ABO*,‡; Meijome, Tomas E. MD, MS*; Mian, Shahzad I. MD*; Woodward, Maria A. MD, MSc*,‡,§

doi : 10.1097/ICO.0000000000002690

October 2021 - Volume 40 - Issue 10 - p 1316-1321

To characterize vision-related quality of life after penetrating keratoplasty (PKP), deep anterior lamellar keratoplasty (DALK), Descemet stripping automated endothelial keratoplasty (DSAEK), and Descemet membrane endothelial keratoplasty (DMEK) using the National Eye Institute Visual Function Questionnaire (NEI-VFQ 9).

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The ABCD Keratoconus Grading System–A Useful Tool to Estimate Keratoconus Progression in the Pediatric Population

Dubinsky-Pertzov, Biana MD, MPH; Reinhardt, Ophir MD; Gazit, Inbal MD; Or, Lior MD; Hecht, Idan MD; Pras, Eran MD; Einan-Lifshitz, Adi MD

doi : 10.1097/ICO.0000000000002632

October 2021 - Volume 40 - Issue 10 - p 1322-1329

To evaluate the ABCD grading system in pediatric keratoconus.

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Long-Term Outcome of Femtosecond Laser–Assisted Keratopigmentation: Using Intacs Channels for Precise Pigment Deposition Within the Cornea

Yin, Han Y. MD; Walter, Keith A. MD

doi : 10.1097/ICO.0000000000002667

October 2021 - Volume 40 - Issue 10 - p 1330-1335

To describe a long-term outcome of a new technique using the femtosecond laser to assist with keratopigmentation (corneal tattooing).

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Effect of Face Mask on Tear Film Stability in Eyes With Moderate-to-Severe Dry Eye Disease

Arriola-Villalobos, Pedro MD, PhD*,†; Burgos-Blasco, Barbara MD†,‡; Vidal-Villegas, Beatriz MD†,‡; Oribio-Quinto, Carlos MD†,‡; Ariño-Gutiérrez, Mayte MD†,‡; Diaz-Valle, David MD, PhD*,†; Benitez-del-Castillo, Jose Manuel MD, PhD†,§

doi : 10.1097/ICO.0000000000002734

October 2021 - Volume 40 - Issue 10 - p 1336-1339

The purpose of this study was to evaluate whether tear film stability worsens with the use of masks in patients with dry eye disease, objectively analyzing the tear film stability using noninvasive tear film breakup time (NITBUT) with and without a face mask.

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Combined Phialemonium curvatum and Acanthamoeba Keratitis: The Importance of Early Diagnosis and Specific Therapy

Roszkowska, Anna M. MD, PhD*; Severo, Alice A. MD*; Biondo, Carmelo MD†; Postorino, Elisa I. MD, PhD*; Inferrera, Leandro MD*; Aragona, Pasquale MD, PhD*

doi : 10.1097/ICO.0000000000002660

October 2021 - Volume 40 - Issue 10 - p 1340-1343

To report the clinical and confocal findings of a unique case of combined Phialemonium curvatum and Acanthamoeba keratitis and to highlight the role of the prompt diagnosis and specific medical treatment in preserving visual function.

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A Case of Black Fungal Keratitis Caused by Biatriospora mackinnonii

Aoki, Takanori MD*; Fukuoka, Hideki MD, PhD*; Inatomi, Tsutomu MD, PhD*,†; Horiuchi, Noriko MD*; Kamei, Katsuhiko MD, PhD‡; Sotozono, Chie MD, PhD*

doi : 10.1097/ICO.0000000000002676

October 2021 - Volume 40 - Issue 10 - p 1344-1347

To report a novel case of fungal keratitis caused by Biatriospora mackinnonii (Pyrenochaeta mackinnonii), a dematiaceous fungus (black fungus) that rarely causes dermatological infection, in a patient treated for ocular cicatricial pemphigoid.

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Assessment of Antimicrobial Activity of Dehydrated Amniotic Membrane in Infectious Keratitis: A Small Retrospective Case Series and In Vitro Study

Oji, Nnaoma M. BS*; Lin, Yijie B. MD, MBA†; Lee, Michele D. MD‡; Cevallos, Ada V. MS†; Keenan, Jeremy D. MD, MPH†; Seitzman, Gerami D. MD†

doi : 10.1097/ICO.0000000000002627

October 2021 - Volume 40 - Issue 10 - p 1348-1352

To describe a small case series of infectious keratitis with poor visual outcomes after amniotic membrane (AM) placement and to prospectively evaluate whether AM demonstrates antibacterial activity in vitro against pathogens commonly isolated from infectious corneal ulcers.

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Atypical Case of Bilateral Chandler Syndrome With Recurrent Band Keratopathy

Agarwal, Mamta MD, FRCS Edin*; Dhiman, Richa MD†; Subramanian, Krishnakumar MD‡

doi : 10.1097/ICO.0000000000002610

October 2021 - Volume 40 - Issue 10 - p 1353-1356

To report a unique case of bilateral Chandler syndrome with recurrent band keratopathy.

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Silk Suture Granuloma 37 Years After Scleral Buckle Surgery: A Case Report

Zein, Mike MD*; Theotoka, Despoina MD, MSc*; Wall, Sarah BS*; Galor, Anat MD, MSPH*,†; Cabot, Florence MD*; Patel, Umangi MD*,‡; Dubovy, Sander MD*,‡; Karp, Carol L. MD*

doi : 10.1097/ICO.0000000000002637

October 2021 - Volume 40 - Issue 10 - p 1357-1359

To present a rare presentation of pyogenic granuloma arising almost 4 decades after a scleral buckle for retinal detachment.

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Simplified, Readily Available Method for the Treatment of Band Keratopathy With Ethylenediaminetetraacetic Acid

Narvaez, Julio MD*,†; Chang, Matthew BS‡; Ing, Jeffrey MD†; De Chance, Daniel§; Narvaez, Joshua J.*

doi : 10.1097/ICO.0000000000002635

October 2021 - Volume 40 - Issue 10 - p 1360-1362

To compare 3 methods for creating ethylenediaminetetraacetic acid (EDTA) solution using readily available Vacutainer tubes for the treatment of band keratopathy.

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Corneal Effects of Tea Tree Oil

Tharmarajah, Brindhan BMed, MD, BScMed (Hons1)*; Coroneo, Minas Theodore BSc (Med) MB BS, MSc, Syd, MD, MS UNSW, FRACS, FRANZCO, FARVO*,†

doi : 10.1097/ICO.0000000000002776

October 2021 - Volume 40 - Issue 10 - p 1363-1364

The purpose of this study is to report a case of corneal epithelial defects resulting from topical treatment of blepharitis with tea tree oil (TTO).

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Cool Cross-Linking: Riboflavin at 4°C for Pain Management After Cross-Linking for Keratoconus Patients, a Randomized Clinical Trial

Saluja, Gunjan MD; Maharana, Prafulla K. MD

doi : 10.1097/ICO.0000000000002703

October 2021 - Volume 40 - Issue 10 - p e19

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Outcomes of ipsilateral Simple Limbal Epithelial Transplantation, Tenonectomy, Mitomycin, and Amniotic Membrane Transplantation for Treatment of Recurrent Pterygium- Letter to editor

Singh, Prabhakar MD; Raj, Amit MS; Gupta, Abhishek MS

doi : 10.1097/ICO.0000000000002726

October 2021 - Volume 40 - Issue 10 - p e19-e20

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Author’s Response to Letter: Outcomes of Ipsilateral Simple Limbal Epithelial Transplant (SLET), Mitomycin, Tenonectomy and Amniotic Membrane Transplantation for Treatment of Recurrent Pterygium

Trinh, Tanya MBBS, FRANZCO*; Mimouni, Michael MD*; Mednick, Zale MD, FRCSC*; Einan-Lifshitz, Adi MD*; Cohen, Eyal MD*; Santaella, Gisella MD*; Sorkin, Nir MD*,†; Slomovic, Allan MD, FRCSC*

doi : 10.1097/ICO.0000000000002749

October 2021 - Volume 40 - Issue 10 - p e20-e21

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